helmholtzeyeinstituteРоссийский офтальмологический журналRussian Ophthalmological Journal2072-00762587-5760Real time Publishers10.21516/2072-0076-2022-15-2-177-185helmholtzeyeinstitute-1012Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEWSПерспективы применения в офтальмологии «умных» контактных линз и переднекамерных электронных имплантовSmart contact lenses and anterior chamber electronic implants: prospects of application in ophthalmologyШамаевД. М.ShamaevD. M.

Дмитрий Михайлович Шамаев, канд. тех. наук, научный сотрудник, доцент

117452

ул. Азовская, д. 39, корп. 1

кафедра «Элементы приборных устройств»

105005

улица 2-я Бауманская, д. 5, корп. 1

Москва

Dmitry M. Shamaev, Cand. of Tech. Sci., researcher, associate professor

117452

39, Bldg. 1, Azovskaya St.

chair of elements of instrument devices

105005

5, Bldg 1, 2nd Baumanskaya St.

Moscow

shamaev.dmitry@yandex.ruЗаяцВ. В.ZayatsV. V.

Виталий Викторович Заяц, канд. мед. наук, директор

117452

ул. Азовская, д. 39, корп. 1

Москва

Vitaly V. Zayats, Cand. of Med. Sci., director

117452

39, Bldg. 1, Azovskaya St.

Moscow

ИомдинаЕ. Н.IomdinaE. N.

Елена Наумовна Иомдина, д-р биол. наук, профессор, главный научный сотрудник

ФГБУ «НМИЦ ГБ им. Гельмгольца»

отдел патологии рефракции, бинокулярного зрения и офтальмоэргономики

105062

ул. Садовая-Черногрязская, д. 14/19

Москва

Elena N. Iomdina, Dr. of Biol. Sci., professor, principal researcher

department of refraction pathology, binocular vision and ophthalmoergonomics

105062

14/19, Sadovaya-Chernogryazskaya St.

Moscow

 

ЛужновП. В.LuzhnovP. V.

Петр Вячеславович Лужнов, канд. тех. наук, доцент

кафедра «Медико-технические информационные технологии»

105005

улица 2-я Бауманская, д. 5, корп. 1

Москва

Petr V. Luzhnov, Cand. of Tech. Sci., associate professor

chair of medical and technical information technologies 

105005

5, Bldg 1, 2nd Baumanskaya St.

Moscow

НикитинО. И.NikitinO. I.

Олег Игоревич Никитин, руководитель проектов, врач-офтальмолог

117452

ул. Азовская, д. 39, корп. 1

ФГАУ НМИЦ «Лечебно-реабилитационный центр»

125367

Иваньковское шоссе, д. 3

Москва

Oleg I. Nikitin, project manager 1 , ophthalmologist

117452

39, Bldg. 1, Azovskaya St.

Treatment and Rehabilitation Center

3, Ivankovskoe Hw.

Moscow

ФГАУ «Ресурсный центр универсального дизайна и реабилитационных технологий»; ФГБУ ВО МГТУ им. Н. Э. БауманаРоссияUniversal design and assistive technology resource center; Bauman Moscow State Technical UniversityRussian FederationФГАУ «Ресурсный центр универсального дизайна и реабилитационных технологий»РоссияUniversal design and assistive technology resource centerRussian FederationМинздрав РоссииРоссияHelmholtz National Medical Research Center of Eye DiseasesRussian FederationФГБУ ВО МГТУ им. Н. Э. БауманаРоссияBauman Moscow State Technical UniversityRussian FederationФГАУ «Ресурсный центр универсального дизайна и реабилитационных технологий»; Минздрав РоссииРоссияUniversal design and assistive technology resource center; Ministry of Health of RussiaRussian Federation202215072022152177185Copyright © Шамаев Д.М., Заяц В.В., Иомдина Е.Н., Лужнов П.В., Никитин О.И., 20222022Шамаев Д.М., Заяц В.В., Иомдина Е.Н., Лужнов П.В., Никитин О.И.Shamaev D.M., Zayats V.V., Iomdina E.N., Luzhnov P.V., Nikitin O.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://roj.igb.ru/jour/article/view/1012

   В России и мире растет частота как системных, так и офтальмологических заболеваний, что связано не в последнюю очередь с тенденцией к увеличению продолжительности жизни. В связи с этим возможность скрининга, ранней диагностики и мониторинга тех или иных показателей организма становится все более значимой. Контактные линзы (КЛ), располагающиеся на глазной поверхности, постоянно смачиваются слезной жидкостью и, благодаря достижениям современной микроэлектроники, могут служить удобным техническим средством для размещения различных датчиков. Существующие в качестве прототипов электронные КЛ (ЭКЛ) позволяют мониторить внутриглазное давление (ВГД), уровень глюкозы, гормонов и других биомаркеров, отражающих течение офтальмологических и системных заболеваний. В обзоре проанализированы публикации, посвященные результатам прототипирования и первых лабораторных применений ЭКЛ. В настоящее время только одна разработка доступна для клинической практики (мониторинг ВГД), остальные находятся на различных этапах исследования, но в перспективе могут получить широкое распространение.

   Systemic and ophthalmological diseases are on the rise the world over, which is, to a large extent, caused by life expectancy growth. Therefore, early diagnosis, screening and monitoringpossibilities of human health parameters is becoming more and more important. Contact lenses, due to being fitted on the eye’s surface, are constantly wetted by tear fluid, and due to present-day microelectronics achievements may be used as a convenient technical means for locating a variety of sensors. The existing prototypes of electronic contact lenses (ECL) are able to monitor intraocular pressure (IOP), levels of glucose, hormones and other biomarkers that reflect the presence of ophthalmic and systemic diseases. The review discusses the publications focused on prototyping results and first laboratory tests. As of today, only one developed device is available for clinical practice (IOP monitoring), others are at different stages of research but have all potentials for being used widely.

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The authors declare that there are no conflicts of interest present.