helmholtzeyeinstituteРоссийский офтальмологический журналRussian Ophthalmological Journal2072-00762587-5760Real time Publishers10.21516/2072-0076-2022-15-4-166-172helmholtzeyeinstitute-1117Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEWSЗаболевания щитовидной железы и их роль в патогенезе глаукомыThyroid disorders and their role in the pathogenesis of glaucomahttps://orcid.org/0000-0003-1361-6704ЧерняковаТ. В.ChernyakovaT. V.

Татьяна Васильевна Чернякова — канд. мед. наук, врач-офтальмолог

Севастопольский проспект, д. 66, Москва, 117593

Tatyana V. Chernyakova — Cand. of Med. Sci., ophthalmologist

 

tat.chernyakova-25@yandex.ruhttps://orcid.org/0000-0002-5965-2471ЗаргарянА. Е.ZargaryanH. Y.

Асмик Ерджаниковна Заргарян — канд. мед. наук, врач-офтальмолог

ул. Пролетарская, д. 7, Балашиха, Московская область, 143980

Hasmik Y. Zargaryan — Cand. of Med. Sci., ophthalmologist

 

https://orcid.org/0000-0002-5597-983XБрежневА. Ю.BrezhnevA. Yu.

Андрей Юрьевич Брежнев — канд. мед. наук, доцент кафедры офтальмологии

ул. Карла Маркса, д. 3, Курск, 305041

Andrey Yu. Brezhnev — Cand. of Med. Sci., associate professor of chair of ophthalmology

 

https://orcid.org/0000-0001-6841-3547ОнуфрийчукО. Н.OnufriychukO. N.

Олег Николаевич Онуфрийчук — канд. мед. наук, врач-офтальмолог

Парковая ул., д. 64–68, Пушкин, Санкт-Петербург, 196603

Oleg N. Onufriychuk — Cand. of Med. Sci., ophthalmologist

 

https://orcid.org/0000-0003-4611-9931ГазизоваИ. Р.GazizovaI. R.

Ильмира Рифовна Газизова — д-р мед. наук, ученый секретарь, заведующая отделением офтальмологии

ул. Академика Павлова, д. 9, Санкт-Петербург, 197376

Ilmira R. Gazizova — Dr. of Med.Sci., scientific secretary, head ofophthalmological department

 

https://orcid.org/0000-0002-4583-6050СелезневА. В.SeleznevА. V.

Алексей Владимирович Селезнев — канд. мед. наук, доцент кафедры оториноларингологии и офтальмологии

пр. Шереметевский, д. 8, Иваново,153012

Аleksey V. Seleznev — Cand. of Med. Sci., assistant professor

 

https://orcid.org/0000-0001-9606-0566КуроедовА. В.KuroyedovА. V.

Александр Владимирович Куроедов — д-р мед. наук, профессор кафедры, начальник отделения

ул. Б. Оленья, д. 8А, Москва, 107014

ул. Островитянова, д. 1, Москва, 117997

Аleksandr V. Kuroyedov — Dr. of Med. Sci., head of ophthalmological department, professor1, chair of ophthalmology

Многопрофильный медицинский центр Банка РоссииРоссияMultifield Medical Center of Bank of RussiaRussian FederationОфтальмологическая клиника «Доктор Глазов»РоссияDoctor Glazov Ophthalmology ClinicRussian FederationФГБОУ ВО «Курский государственный медицинский университет» Минздрава РоссииРоссияKursk State Medical UniversityRussian FederationФГБУ «НМИЦ детской травматологии и ортопедии им. Г.И. Турнера» Минздрава РоссииРоссияG.Turner National Medical Research Center for Children’s Orthopedics and Trauma SurgeryRussian FederationФГУН «Институт мозга человека им. Н.П. Бехтеревой» РАНРоссияN.P. Bekhtereva Institute of Human Brain, RASRussian FederationФГБОУ ВО «Ивановская государственная медицинская академия» Минздрава РоссииРоссияIvanovo State Medical AcademyRussian FederationФГУ «Центральный военный клинический госпиталь им. П.В. Мандрыка» Минздрава России; Российский национальный исследовательский медицинский университет им. Н.И. Пирогова Минздрава РоссииРоссияMandryka Central Clinical Hospital; N.I. Pirogov Russian National Research Medical UniversityRussian Federation202214122022154166172Copyright © Чернякова Т.В., Заргарян А.Е., Брежнев А.Ю., Онуфрийчук О.Н., Газизова И.Р., Селезнев А.В., Куроедов А.В., 20222022Чернякова Т.В., Заргарян А.Е., Брежнев А.Ю., Онуфрийчук О.Н., Газизова И.Р., Селезнев А.В., Куроедов А.В.Chernyakova T.V., Zargaryan H.Y., Brezhnev A.Y., Onufriychuk O.N., Gazizova I.R., Seleznev А.V., Kuroyedov А.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://roj.igb.ru/jour/article/view/1117

Анализ литературы подтверждает взаимосвязь патологии щитовидной железы и глаукомы. Пациенты с диффузно-токсическим и эндемическим зобом представляют группу особо высокого риска развития глаукомы, с аутоиммунным тиреоидитом — группу умеренного риска. У пациентов, страдающих эндокринной офтальмопатией, в возрасте старше 40 лет распространенность первичной открытоугольной глаукомы (ПОУГ) достоверно связана с мужским полом и длительностью заболевания более 60 мес. Повышенный риск развития ПОУГ при гипотиреозе отмечен у мужчин со средним возрастом 69 лет. Сопровождающая эндокринную патологию офтальмогипертензия в большинстве случаев не нуждается в местном гипотензивном лечении. Основная патогенетически обоснованная терапия заболеваний щитовидной железы приводит к снижению уровня внутриглазного давления и улучшению оттока жидкости из глаза.

The literature analysis confirms the interrelationship of thyroid gland pathology and glaucoma. Patients with diffusetoxic goiter (DTG) and endemic goiter have an especially high risk of developing glaucoma, while those with autoimmune thyroiditis face a moderate risk. The prevalence of primary open angle glaucoma (POAG) in patients over 40 with endocrine ophthalmopathy is reliably associated with the male gender and the duration of the disease longer than 60 months. An increased risk of POAG is noted in men with hypothyroidism averagely aged 69. In most cases, ophthalmic hypertension that accompanies endocrine pathology does not need any topical hypotensive treatment. The main pathogenetically validated therapy of thyroid disorders results in a reduction of IOP level and an improvement of fluid outflow from the eye.

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The authors declare that there are no conflicts of interest present.