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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">helmholtzeyeinstitute</journal-id><journal-title-group><journal-title xml:lang="ru">Российский офтальмологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Ophthalmological Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0076</issn><issn pub-type="epub">2587-5760</issn><publisher><publisher-name>Real time Publishers</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21516/2072-0076-2017-10-3-78-83</article-id><article-id custom-type="elpub" pub-id-type="custom">helmholtzeyeinstitute-112</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Аберрации волнового фронта у детей с миопией и гиперметропией до и после циклоплегии</article-title><trans-title-group xml:lang="en"><trans-title>Wavefront aberrations in children with myopia and hyperopia before and after cycloplegia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарутта</surname><given-names>Е. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarutta</surname><given-names>E. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арутюнян</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Arutyunyan</surname><given-names>S. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смирнова</surname><given-names>Т. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Smirnova</surname><given-names>T. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Московский НИИ глазных болезней им. Гельмгольца» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Helmholtz Research Institute of Eye Diseases, Moscow, Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>03</day><month>10</month><year>2018</year></pub-date><volume>10</volume><issue>3</issue><fpage>78</fpage><lpage>83</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тарутта Е.П., Арутюнян С.Г., Смирнова Т.С., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Тарутта Е.П., Арутюнян С.Г., Смирнова Т.С.</copyright-holder><copyright-holder xml:lang="en">Tarutta E.P., Arutyunyan S.G., Smirnova T.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://roj.igb.ru/jour/article/view/112">https://roj.igb.ru/jour/article/view/112</self-uri><abstract><p>Целью данной работы явилось сравнительное изучение влияния циклоплегии на аберрации волнового фронта у детей с миопией и гиперметропией. Материал и методы . В исследовании участвовали 20 пациентов (39 глаз) с миопической (в среднем -5,2±1,5 дптр) и 26 пациентов (53 глазa) с гиперметропической рефракцией (средняя рефракция +3,1±1,15 дптр) в возрасте от 5 до 17 лет (в среднем 11,6±0,6 лет). Всем пациентам проводили аберрометрию волнового фронта в затемненной комнате до и после медикаментозной циклоплегии (1% циклопентолат дегидрохлорид 2 раза с интервалом 10 минут, аберрометрия через 30 минут после первого закапывания) на аберрометре OPD-Scan III, Nidek. Аберрации низшего и высшего порядков анализировали, выбирая ширину зрачка 3 мм, как без циклоплегии, так и в условиях циклоплегии (в последнем случае - с помощью выбора 3 мм зоны). Исследовали общие аберрации (total RMS). Из коэффициентов Цернике были рассчитаны среднеквадратичное отклонение суммарных аберраций высшего порядка (RMS HOAs), вертикальный и горизонтальный наклон (C1-tilt1, C2-tilt2), вертикальные и горизонтальные трефойл (C5-trefoil 6, C8-trefoil 9), вертикальная и горизонтальная кома (C6-coma7, C7-coma8) и сферическая аберрация (S4+S8+S12). Результаты. Как при миопии, так и при гиперметропии на фоне циклоплегии обнаружилась недостоверная тенденция к повышению общего уровня абeрраций высшего порядка, а также cферическoй аберрации. В естественных условиях при миопии уровень аберраций tilt1, горизонтальный трефойл и coma7 оказались достоверно выше, а coma8 и tilt2 - достоверно ниже, чем при гиперметропии. В миопических глазах достоверных изменений всех исследованных HOAs после циклоплегии по сравнению с исходным состоянием не обнаружено. В глазах с гиперметропией обнаружены достоверные изменения: увеличение горизонтального трефойлa и уменьшение горизонтальной комы. Обнаружилась также недостоверная тенденция к увеличению Tilt1 и coma7 и уменьшению вертикального трефойлa и tilt2. Заключение . В естественных условиях при ширине зрачка 3 мм общий уровень аберраций оптической системы глаз с миопией и гиперметропией у детей достоверно не различается, в то время как структура волнового фронта в указанных группах имеет существенные отличия. Выявленные различия структуры волнового фронта и ее динамики на фоне циклоплегии могут свидетельствовать о разном состоянии аккомодационного аппарата, в частности, цилиарной мышцы и связочного аппарата хрусталика, при миопии и гиперметропии. Для цитирования: Тарутта Е.П., Арутюнян С.Г., Смирнова Т.С. Аберрации волнового фронта у детей с миопией и гиперметропией до и после циклоплегии. Российский офтальмологический журнал. 2017; 10 (3): 78-83. doi: 10.21516/2072-0076-2017-10-3-78-83</p></abstract><trans-abstract xml:lang="en"><p>Purpose: a comparative study of the effect of cycloplegia on wavefront aberration in children with myopia and hyperopia. Material and methods. The study involved 20 patients (39 eyes) with myopic refraction (averagely -5.2 ± 1,5 D) and 26 patients (52 eyes) with hyperopic refraction (averagely +3.1 ± 1.15 D), aged 5 to 17 (mean age 11.6 ± 0.6 years). All patients underwent wavefront aberrometry in a darkened room before and after a cycloplegic drug administration (1 % cyclopentolate dehydrochloride 2 times with an interval of 10 minutes, aberrometry 30 minutes after the first instillation) using the aberrometer OPD-Scan III, Nidek. Aberrations of the lower and higher orders were analyzed with a pupil 3 mm wide, both without and under cycloplegia (in the latter case, a 3 mm band was chosen). Total aberrations (RMS) were studied. Zernike coefficients were used to calculate the standard deviation of total higher order aberrations (RMS HOAs), the vertical and the horizontal tilt (C1-tilt1, C2-tilt2), the vertical and horizontal trefoil (C5-trefoil 6, C8-trefoil 9), the vertical and horizontal coma (C6-coma7, C7-coma8), and spherical aberration (S4 + S8 + S12). Results. Both myopia and hyperopia treated with cycloplegia showed a statistically insignificant increasing trend of higher order aberrations and spherical aberration. Under natural conditions, the levels of tilt1 aberration, horizontal trefoil and coma7 proved significantly higher in myopia than in hyperopia, while coma8 and tilt2 turned out to be significantly lower than in hyperopia. In myopic eyes, no significant changes were found in any of the examined HOAs after cycloplegiaas compared to the initial state. In contrast, significant changes were found in hyperopia: an increase in horizontal trefoil and a decrease in horizontal coma. An insignificant trend towards an increase in Tilt1 and coma7 and toward a reduction in the vertical trefoil and tilt2 was revaeled. Conclusions. Under natural conditions, a 3-mm wide pupil shows no statistically significant difference between the total level of aberrations of the optical system of the myopic eye and hyperopic eyes in children, while the the wavefront structures in these groups demonstrate essential differences. The differences revealed in the wavefront structure and its dynamics under cycloplegia may indicate differences in the accommodation apparatus, in particular, the ciliary muscles and ligaments of the lens for myopia and hyperopia. For citations: Tarutta E.P., Аrutyunyan S.G., Smirnova T.S. Wavefront aberrations in children with myopia and hyperopia before and after cycloplegia. Russian ophthalmological journal. 2017; 10 (3): 78-83. doi: 10.21516/2072-0076-2017-10-3-78-83 (in Russian).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>волновой фронт</kwd><kwd>аберрации</kwd><kwd>циклоплегия</kwd><kwd>гиперметропия</kwd><kwd>миопия</kwd><kwd>wavefront</kwd><kwd>aberrations</kwd><kwd>cycloplegia</kwd><kwd>hyperopia</kwd><kwd>myopia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hazel C.A., Cox M.J., Strang N.C. Wave front aberration and its relationship to the accommodative stimulus-response function in myopic subjects. Optom Vis Sci. 2003; 80: 151-8. doi: 10.1097/00006324-200302000-00011</mixed-citation><mixed-citation xml:lang="en">Hazel C.A., Cox M.J., Strang N.C. Wave front aberration and its relationship to the accommodative stimulus-response function in myopic subjects. 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