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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">helmholtzeyeinstitute</journal-id><journal-title-group><journal-title xml:lang="ru">Российский офтальмологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Ophthalmological Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0076</issn><issn pub-type="epub">2587-5760</issn><publisher><publisher-name>Real time Publishers</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21516/2072-0076-2023-16-1-41-46</article-id><article-id custom-type="elpub" pub-id-type="custom">helmholtzeyeinstitute-1166</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Особенности клинических проявлений, течения и результаты лечения ретинита Коатса у детей</article-title><trans-title-group xml:lang="en"><trans-title>Clinical manifestation, course and treatment results of Coats disease in children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коголева</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kogoleva</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Людмила Викторовна Коголева — д-р мед. наук, заведующая детским консультативно-поликлиническим отделением</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва,105062</p></bio><bio xml:lang="en"><p>Ludmila V. Kogoleva — Dr. of Med. Sci., head of children out-patient department</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Маргарита Сергеевна Иванова — врач детского консультативно-поликлинического отделения</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва,105062</p></bio><bio xml:lang="en"><p>Margarita S. Ivanova — ophthalmologist, children’s polyclinic department</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Демченко</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Demchenko</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елена Николаевна Демченко — канд. мед. наук, научный сотрудник отдела патологии глаз у детей</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва,105062</p></bio><bio xml:lang="en"><p>Elena N. Demchenko — Cand. of Med. Sci., ophthalmologist, department of children´s eye pathology</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><email xlink:type="simple">ddddemchenko@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Судовская</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sudovskaya</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Татьяна Викторовна Судовская — д-р мед. наук, врач детского консультативно-поликлинического отделения</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва,105062</p></bio><bio xml:lang="en"><p>Tatyana V. Sudovskaya — Dr. of Med. Sci., ophthalmologist, children’s polyclinic department</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бобровская</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bobrovskaya</surname><given-names>Ju. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юлия Андреевна Бобровская — врач детского консультативно-поликлинического отделения</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва,105062</p></bio><bio xml:lang="en"><p>Julya A. Bobrovskaya — ophthalmologist, children’s polyclinic department</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кокоева</surname><given-names>Н. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Kokoeva</surname><given-names>N. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нина Шотаевна Кокоева — врач детского консультативно-поликлинического отделения</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва,105062</p></bio><bio xml:lang="en"><p>Nina Sh. Kokoeva — ophthalmologist, children’s polyclinic department</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макарова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анастасия Александровна Макарова — врач детского консультативного поликлинического отделения</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва,105062</p></bio><bio xml:lang="en"><p>Anastasya A. Makarova — ophthalmologist, children’s polyclinic department</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ глазных болезней им. Гельмгольца» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Helmholtz National Medical Research Center of Eye Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>14</day><month>03</month><year>2023</year></pub-date><volume>16</volume><issue>1</issue><fpage>41</fpage><lpage>46</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Коголева Л.В., Иванова М.С., Демченко Е.Н., Судовская Т.В., Бобровская Ю.А., Кокоева Н.Ш., Макарова А.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Коголева Л.В., Иванова М.С., Демченко Е.Н., Судовская Т.В., Бобровская Ю.А., Кокоева Н.Ш., Макарова А.А.</copyright-holder><copyright-holder xml:lang="en">Kogoleva L.V., Ivanova M.S., Demchenko E.N., Sudovskaya T.V., Bobrovskaya J.A., Kokoeva N.S., Makarova A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://roj.igb.ru/jour/article/view/1166">https://roj.igb.ru/jour/article/view/1166</self-uri><abstract><p>Цель работы — анализ клинических проявлений, течения и результатов лечения ретинита Коатса у детей. Материал и методы. Проведен ретроспективный анализ медицинской документации 59 пациентов (83 % из них — мальчики) с ретинитом Коатса, проходивших комплексное обследование и лечение в период с 2018 по 2021 г. После верификации диагноза дети были госпитализированы в стационар для лечения. Лазеркоагуляция сетчатки выполнена на 61 глазу, введение препаратов — ингибиторов ангиогенеза — на одном глазу, микрохирургические вмешательства — на 5 глазах. Результаты. Возраст детей на момент выявления заболевания варьировал от 1 года до 16 лет. Односторонний процесс наблюдался в 97 % случаев. Улучшение анатомического состояния и органосохранный эффект достигнуты в 87 %. Повышение остроты зрения удалось добиться только на 19 (31,1 %) глазах с начальной и развитой стадиями ретинита Коатса. На основании нашего опыта, анализа полиморфизма клинических проявлений, функционального прогноза и дифференцированных подходов к лечению, зависящих от преобладающих клинических симптомов, предложен вариант клинической классификации ретинита Коатса. Заключение. Для своевременной диагностики данного заболевания наиболее серьезное внимание следует уделять тщательному обследованию пациентов первой декады жизни. Только ранняя диагностика и своевременное лечение позволят добиться не только органосохранного, но и функционального результата.</p></abstract><trans-abstract xml:lang="en"><p>Purpose: to analyze the clinical manifestations, course, and results of treatment of Coats disease in children. Materials and methods. We performed a retrospective analysis of medical records of 59 patients with Coats retinitis (83 % were boys) who had been comprehensively examined and treated between 2018 and 2021. After the diagnosis was verified, the children were hospitalized for treatment. Retinal laser coagulation was performed on 61 eyes, angiogenesis inhibitors were administered on 1 eye, and 5 eyes received microsurgical interventions. Results. At the time of disease detection, the children’s age varied from 1 to 16 years. In 97 % of cases, the process was unilateral. An improvement of the anatomical condition and the eye-preserving effect were achieved in 87 %. Visual acuity could only be increased in 19 eyes (31.1 %), all with the initial or the advanced stages of Coats retinitis. Proceeding from our experience, the analysis of polymorphism of clinical manifestations, functional prognosis and differentiated approach to treatment depending on the prevailing clinical symptoms, we suggest a new variant of clinical classification of Coats retinitis. Conclusion. In order to ensure a timely diagnosis of the disease, a very thorough examination of patients in the first decade of life is required. Only an early diagnosis and timely treatment can help achieve not only an eye-preserving effect but also functional results.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>болезнь Коатса</kwd><kwd>телеангиэктазии</kwd><kwd>экссудативная отслойка сетчатки</kwd><kwd>лазеркоагуляция сетчатки</kwd><kwd>дети</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Coats disease</kwd><kwd>telangiectasia</kwd><kwd>exudative retinal detachment</kwd><kwd>retinal laser</kwd><kwd>children</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гурко Т.С., Гойдин А.П. Клинические особенности и лечение ретинита Коатса. Вестник тамбовского университета. Серия: Естественные и технические науки. 2017; 22 (4): 638–42. doi: 10/20310/1810-0198-2017-22-4-63 8-642</mixed-citation><mixed-citation xml:lang="en">Gurko T.S., Goydin A.P. Clinical features and treatment of Coates retinitis. 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