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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">helmholtzeyeinstitute</journal-id><journal-title-group><journal-title xml:lang="ru">Российский офтальмологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Ophthalmological Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0076</issn><issn pub-type="epub">2587-5760</issn><publisher><publisher-name>Real time Publishers</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21516/2072-0076-2023-16-2-47-53</article-id><article-id custom-type="elpub" pub-id-type="custom">helmholtzeyeinstitute-1232</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Анатомо-оптические параметры и аберрации оптической системы глаза при анизометропической миопии</article-title><trans-title-group xml:lang="en"><trans-title>Anatomical and optical parameters and aberrations of the optical system of the eye in anisometropic myopia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8480-0894</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нероев</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Neroev</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владимир Владимирович Нероев, академик РАН, д-р мед. наук, профессор, начальник отдела патологии сетчатки и зрительного нерва, директор, </p><p>ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Vladimir V. Neroev, Аcademician of the RAS, Dr. of Med. Sci., professor, head of the  department of pathology of the retina and optic nerve, director, </p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8864-4518</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарутта</surname><given-names>Е. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarutta</surname><given-names>E. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елена Петровна Тарутта, д-р мед. наук, профессор, начальник отдела патологии рефракции, бинокулярного зрения и офтальмоэргономики, </p><p>ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Elena P. Tarutta, Dr. of Med. Sci., professor, head of the department of refraction pathology, binocular vision and ophthalmoergonomics,</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4998-7323</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ходжабекян</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khodzhabekyan</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нарине Володяевна Ходжабекян, канд. мед. наук, ведущий научный сотрудник  отдела патологии рефракции, бинокулярного зрения и офтальмоэргономики, </p><p>ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Narine V. Khodzhabekyan, Cand. of Med. Sci., leading researcher of the department of refraction pathology, binocular vision and ophthalmoergonomics, </p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5674-2869</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ханджян</surname><given-names>А. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Khandzhian</surname><given-names>A. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ануш Тиграновна Ханджян, канд. мед. наук, старший научный сотрудник отдела патологии сетчатки и зрительного нерва, </p><p>ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Anush T. Khandzhyan, Cand. of Med. Sci., senior researcher of the department of pathology of the retina and optic nerve, </p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4711-3374</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арутюнян</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Harutyunyan</surname><given-names>S. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сона Гришаевна Арутюнян, канд. мед. наук, научный сотрудник отдела патологии рефракции, бинокулярного зрения и офтальмоэргономики, </p><p>ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Sona G. Harutyunyan, Cand. of Med. Sci., researcher of the department of refraction pathology, binocular vision and ophthalmoergonomics,</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ глазных болезней им. Гельмгольца» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Helmholtz National Medical Research Center of Eye Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2023</year></pub-date><volume>16</volume><issue>2</issue><fpage>47</fpage><lpage>53</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Нероев В.В., Тарутта Е.П., Ходжабекян Н.В., Ханджян А.Т., Арутюнян С.Г., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Нероев В.В., Тарутта Е.П., Ходжабекян Н.В., Ханджян А.Т., Арутюнян С.Г.</copyright-holder><copyright-holder xml:lang="en">Neroev V.V., Tarutta E.P., Khodzhabekyan N.V., Khandzhian A.T., Harutyunyan S.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://roj.igb.ru/jour/article/view/1232">https://roj.igb.ru/jour/article/view/1232</self-uri><abstract><p>Цель работы — сравнение анатомо-оптических и аберрометрических параметров парных глаз у пациентов с приобретенной и врожденной анизометропической миопией.</p><sec><title>Материал и методы</title><p>Материал и методы. Двадцать два пациента (44 глаза) в возрасте 18–35 (в среднем 25,2 года) лет с анизометропической приобретенной и врожденной миопией обследованы на анализаторе оптической системы глаза Galilei G6 (Ziemer, Швейцария). Общие, роговичные и внутренние аберрации глаза определяли на аберрометре OPD-Scan III (Nidek).</p></sec><sec><title>Результаты</title><p>Результаты. Аксиальная длина глаза как в группе с приобретенной, так и с врожденной анизометропической миопией была выше на глазу с большей миопией. При врожденной миопии выявлена большая асферичность роговицы на более миопичном глазу и более высокий астигматизм, чем при приобретенной миопии. Общий RMS HOA при врожденной миопии был достоверно выше на худшем глазу, чем на лучшем (в среднем 1,07 и 0,68 дптр соответственно), и выше, чем при приобретенной миопии. Все общие аберрации высшего порядка при врожденной миопии оказались выше на худшем глазу, чем на парном, при приобретенной — только total coma была выше на худшем глазу. Роговичные аберрации при приобретенной анизометропической миопии не различались на парных глазах. При врожденной миопии total tilt был достоверно больше на худшем глазу, а total coma и сферическая аберрация — меньше, с переходом в отрицательные значения (р &lt; 0,05).</p></sec><sec><title>Заключение</title><p>Заключение. Выявленные различия волнового фронта глаз с анизометропической врожденной и приобретенной миопией являются скорее следствием анатомо-оптических различий — длины глаза и топографии роговицы, чем причиной возникновения анизометропии.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose: to compare anatomical and optical parameters and aberrations of both eyes in patients with acquired and congenital anisometropic myopia.</p></sec><sec><title>Material and methods</title><p>Material and methods. 22 patients (44 eyes) aged 18–35 (averagely, 25.2) with acquired and congenital anisometropic myopia were examined using the Galilei G6 optical eye system analyzer (Ziemer, Switzerland). The analysis of total, corneal and internal aberrations of the eye was carried out on an OPD-Scan III (Nidek) aberrometer.</p></sec><sec><title>Results</title><p>Results. In both groups with acquired and congenital anisometropic myopia, the axial length of the higher myopic eye was greater than that of the fellow eye. A greater asphericity and higher astigmatism of the cornea were revealed in higher myopic eyes of patients with congenital myopia as compared to acquired myopia. The total RMS HOA in congenital myopia was significantly greater in the higher myopic eye compared to the fellow eye (1.07 D and 0.68 D, respectively) and greater than in cases of acquired myopia. All HOA were greater in higher myopic eyes as compared to the fellow ones in cases of congenital myopia. In case of acquired myopia only the total coma appeared to be greater in the higher myopic eye. Corneal aberrations in acquired anisometropic myopia did not differ in the paired eyes. In case of congenital myopia, the total tilt was significantly greater in the higher myopic eye, and total coma and spherical aberration have lower values, even with a transition to negative ones (p &lt; 0.05).</p></sec><sec><title>Conclusion</title><p>Conclusion. The revealed differences of the wavefront of the eyes with anisometropic congenital and acquired myopia are rather a consequence of anatomical and optical differences (the axial length of the eyes and the topography of the cornea), than the cause of anisometropia.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>анизометропия</kwd><kwd>аберрации</kwd><kwd>миопия</kwd><kwd>сферическая аберрация</kwd><kwd>длина передне-задней оси глаза</kwd></kwd-group><kwd-group xml:lang="en"><kwd>anisometropia</kwd><kwd>aberrations</kwd><kwd>myopia</kwd><kwd>spherical aberration</kwd><kwd>axial length</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Vincent SJ, Collins MJ, Read SA, Carney L. G. Myopic anisometropia: ocular characteristics and aetiological considerations. 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