helmholtzeyeinstituteРоссийский офтальмологический журналRussian Ophthalmological Journal2072-00762587-5760Real time Publishers10.21516/2072-0076-2024-17-1-125-129helmholtzeyeinstitute-1440Research ArticleВ ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУFOR OPHTHALMOLOGY PRACTITIONERSХориоретинальная складчатость как симптом новообразования орбиты. Клиническое наблюдениеChorioretinal folds as a symptom of orbital neoplasia. A case reporthttps://orcid.org/0000-0002-7472-4883СветозарскийС. Н.SvetozarskiyS. N.

Нижневолжская наб., д. 2, Нижний Новгород, 603001

пл. Минина и Пожарского, д. 10/1, Нижний Новгород, 603005

Sergey N. Svetozarskiy — Cand. of Med. Sci., ophthalmologist, Volga District Medical Center; assistant of chair of eye diseases, Privolzhsky Research Medical University

2, Nizhnevolzhskaya Quay, Nizhny Novgorod, 603001

10/1, Minin and Pozharsky Square, Nizhny Novgorod, 603005

svetozarskij@rambler.ruИгонинГ. С.IgoninG. S.

пл. Минина и Пожарского, д. 10/1, Нижний Новгород, 603005

Gleb S. Igonin — resident of of chair of eye diseases

10/1, Minin and Pozharsky Square, Nizhny Novgorod, 603005

ФБУЗ «Приволжский окружной медицинский центр» Федерального медико-биологического агентства; ФГБОУ ВО «Приволжский исследовательский медицинский университет» Минздрава РоссииРоссияVolga District Medical Center; Privolzhsky Research Medical UniversityRussian FederationФГБОУ ВО «Приволжский исследовательский медицинский университет» Минздрава РоссииРоссияPrivolzhsky Research Medical UniversityRussian Federation202426032024171125129Copyright © Светозарский С.Н., Игонин Г.С., 20242024Светозарский С.Н., Игонин Г.С.Svetozarskiy S.N., Igonin G.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://roj.igb.ru/jour/article/view/1440

Хориоретинальные складки — это волнообразное изменение формы сосудистой оболочки и наружных слоев сетчатки, возникающее в результате нарушения соотношения площадей поверхности склеры, хориоидеи и сетчатки. Спектр этиологических факторов развития данного состояния включает гипотонию глазного яблока, задний склерит, внутричерепную гипертензию, опухолевые и воспалительные заболевания орбиты. Патогенез хориоретинальных складок обусловлен механическим смещением или утолщением сосудистой оболочки, утолщением и изменением контура склеры, а также отеком оболочек зрительного нерва. На примере клинического наблюдения пациентки 45 лет с остро возникшей гиперметропией и хориоретинальной складчатостью рассматривается клинико-инструментальный алгоритм дифференциальной диагностики причин данного состояния.

Chorioretinal folds are a wave-like change of the form of the choroid and outer retinal layers resulting from changes in the surface area ratio of the sclera, the choroid, and the retina. The range of etiological factors for this condition includes eyeball hypotonia, posterior scleritis, intracranial hypertension, tumor and inflammatory diseases of the orbit. The pathogenesis of chorioretinal folds is determined by mechanical displacement or thickening of the vasculature, sclera thickening and changes in its contour, as well as edema of the optic nerve coats. We present a clinical case of a 45-year-old female patient with acute hyperopia and chorioretinal folds, focusing on the clinical and instrumental algorithm of differential diagnostics of the causes of this condition.

хориоретинальные складкихирургические осложнениягипотония глазановообразования орбитызадний склеритchorioretinal foldssurgical complicationseye hypotoniaorbital neoplasmsposterior scleritisReferencesAgrawal M, Tripathy K. Choroidal Folds. 2022. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022. PMID: 32491704Agrawal M, Tripathy K. Choroidal Folds. 2022. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022. PMID: 32491704Grosso D, Borrelli E, Sacconi R, Bandello F, Querques G. Recognition, diagnosis and treatment of chorioretinal folds: Current perspectives. Clin Ophthalmol. 2020; 14: 3403–9. https://doi.org/10.2147/OPTH.S241002Grosso D, Borrelli E, Sacconi R, Bandello F, Querques G. Recognition, diagnosis and treatment of chorioretinal folds: Current perspectives. Clin Ophthalmol. 2020; 14: 3403–9. https://doi.org/10.2147/OPTH.S241002Newell FW. Choroidal folds. The seventh Harry Searls Gradle Memorial lecture. Am J Ophthalmol 1973 Jun; 75 (6): 930–42. PMID: 4575341Newell FW. Choroidal folds. The seventh Harry Searls Gradle Memorial lecture. Am J Ophthalmol 1973 Jun; 75 (6): 930–42. PMID: 4575341Tesfaw AK, Batra NN, Phan CT, Woldegiorgis WK, Melesse MA. Intermittent and unilateral chorioretinal folds due to combined chiari 1 malformation and basilar invagination. Case Rep Ophthalmol. 2022; 13 (2): 374–81. https://doi.org/10.1159/000524750Tesfaw AK, Batra NN, Phan CT, Woldegiorgis WK, Melesse MA. Intermittent and unilateral chorioretinal folds due to combined chiari 1 malformation and basilar invagination. Case Rep Ophthalmol. 2022; 13 (2): 374–81. https://doi.org/10.1159/000524750Olsen TW, Palejwala NV, Lee LB, Bergstrom CS, Yeh S. Chorioretinal folds: associated disorders and a related maculopathy. Am J Ophthalmol. 2014; 157 (5): 1038–47.e1. https://doi.org/10.1016/j.ajo.2014.02.021Olsen TW, Palejwala NV, Lee LB, Bergstrom CS, Yeh S. Chorioretinal folds: associated disorders and a related maculopathy. Am J Ophthalmol. 2014; 157 (5): 1038–47.e1. https://doi.org/10.1016/j.ajo.2014.02.021Jaworski A, Wolffsohn JS, Napper GA. Aetiology and management of choroidal folds. Clin Exp Optom. 1999; 82 (5): 169–76. https://doi.org/10.1111/j.1444-0938.1999.tb06638.xJaworski A, Wolffsohn JS, Napper GA. Aetiology and management of choroidal folds. Clin Exp Optom. 1999; 82 (5): 169–76. https://doi.org/10.1111/j.1444-0938.1999.tb06638.xBagnis A, Cutolo CA, Corallo G, et al. Chorioretinal folds: a proposed diagnostic algorithm. Int Ophthalmol. 2019; 39 (11): 2667–73. https://doi.org/10.1007/s10792-019-01083-yBagnis A, Cutolo CA, Corallo G, et al. Chorioretinal folds: a proposed diagnostic algorithm. Int Ophthalmol. 2019; 39 (11): 2667–73. https://doi.org/10.1007/s10792-019-01083-yGass JD. Radial chorioretinal folds. A sign of choroidal neovascularization. Arch Ophthalmol. 1981; 99 (6): 1016–8. https://doi.org/10.1001/archopht.1981.03930011016006Gass JD. Radial chorioretinal folds. A sign of choroidal neovascularization. Arch Ophthalmol. 1981; 99 (6): 1016–8. https://doi.org/10.1001/archopht.1981.03930011016006Friberg TR. The etiology of choroidal folds. A biomechanical explanation. Graefes Arch Clin Exp Ophthalmol. 1989; 227 (5): 459–64. https://doi.org/10.1007/bf02172899Friberg TR. The etiology of choroidal folds. A biomechanical explanation. Graefes Arch Clin Exp Ophthalmol. 1989; 227 (5): 459–64. https://doi.org/10.1007/bf02172899Leahey AB, Brucker AJ, Wyszynski RE, Shaman P. Chorioretinal folds. A comparison of unilateral and bilateral cases. Arch Ophthalmol. 1993; 111 (3): 357–9. https://doi.org/10.1001/archopht.1993.01090030075042Leahey AB, Brucker AJ, Wyszynski RE, Shaman P. Chorioretinal folds. A comparison of unilateral and bilateral cases. Arch Ophthalmol. 1993; 111 (3): 357–9. https://doi.org/10.1001/archopht.1993.01090030075042Иcраелян Ш.О., Павлова О.Ю., Серова Н.С., Саакян С.В., Амирян А.Г. Функциональная мультиспиральная компьютерная томография при псевдотуморе орбиты. Российский электронный журнал лучевой диагностики. 2020; 10 (3): 143–9. https://doi.org/10.21569/2222-7415-2020-10-3-143-149Israelyan Sh.O., Pavlova O.Yu., Serova N.S., Saakyan S.V., Amiryan A.G. Functional multispiral computed tomography of orbital pseudotumour. REJR 2020; 10 (3): 143–9 (In Russ.). https://doi.org/10.21569/2222-7415-2020-10-3-143-149Gündüz AK, Shields CL, Bekdemir Ş, Shields JA. Multimodal imaging of chorioretinal folds induced by orbital vascular malformation in two cases. Eur J Ophthalmol. 2022; 32 (1): NP212–NP217. https://doi.org/10.1177/1120672120957582Gündüz AK, Shields CL, Bekdemir Ş, Shields JA. Multimodal imaging of chorioretinal folds induced by orbital vascular malformation in two cases. Eur J Ophthalmol. 2022; 32 (1): NP212–NP217. https://doi.org/10.1177/1120672120957582Jacobsen AG, Toft PB, Prause JU, Vorum H, Hargitai J. Long term follow-up of persistent choroidal folds and hyperopic shift after complete removal of a retrobulbar mass. BMC Res Notes. 2015; 8: 678. https://doi.org/10.1186/s13104-015-1610-1Jacobsen AG, Toft PB, Prause JU, Vorum H, Hargitai J. Long term follow-up of persistent choroidal folds and hyperopic shift after complete removal of a retrobulbar mass. BMC Res Notes. 2015; 8: 678. https://doi.org/10.1186/s13104-015-1610-1Еричев В.П., Петров С.Ю., Орехова Н.А., Эльмурзаева Л.Х. Гипотоническая макулопатия после глаукомной хирургии: механизмы развития, методы профилактики и терапии. РМЖ. Клиническая офтальмология. 2020; 20 (1): 26–31. https://doi.org/10.32364/2311-7729-2020-20-1-26-31Erichev V.P., Petrov S.Yu., Orekhova N.A., El’murzaeva L.Kh. Hypotony maculopathy after glaucoma surgery: pathogenic mechanisms, diagnostic tools, and treatment modalites. Russian journal of clinical ophthalmology. 2020; 20 (1): 26–31 (In Russ.). https://doi.org/10.32364/2311-7729-2020-20-1-26-31Wang Q, Thau A, Levin AV, Lee D. Ocular hypotony: A comprehensive review. Surv Ophthalmol. 2019; 64 (5): 619–38. https://doi.org/10.1016/j.survophthal.2019.04.006Wang Q, Thau A, Levin AV, Lee D. Ocular hypotony: A comprehensive review. Surv Ophthalmol. 2019; 64 (5): 619–38. https://doi.org/10.1016/j.survophthal.2019.04.006Серова Н.С., Исраелян Ш.О., Павлова О.Ю. и др. Возможности функциональной МСКТ в диагностике гемангиомы орбиты. Российский электронный журнал лучевой диагностики. 2019; 9 (4): 208–14. https://doi.org/10.21569/2222-7415-2019-9-4-208-214Serova N.S., Israelyan Sh.O., Pavlova O.Yu., et al. The possibilities of the functional msct in diagnostics of orbital hemangioma. REJR. 2019; 9 (4): 208–14 (In Russ.). https://doi.org/10.21569/2222-7415-2019-9-4-208-214Саакян С.В., Вальский В.В., Бородин Ю.И., Амирян А.Г. Брахитерапия внутриглазных опухолей. Эффективная фармакотерапия. 2019; 15 (17): 8–10.Saakjan S.V., Val'skij V.V., Borodin Yu.I., Amiryan A.G. Brachytherapy of intraocular tumors. Effective pharmacotherapy. 2019; 15 (17): 8–10 (In Russ.).Heimann H, Bopp S. Retinal folds following retinal detachment surgery. Ophthalmologica. 2011; 226 Suppl 1: 18–26. https://doi.org/10.1159/000328380Heimann H, Bopp S. Retinal folds following retinal detachment surgery. Ophthalmologica. 2011; 226 Suppl 1: 18–26. https://doi.org/10.1159/000328380Валях М.А. Изменения зрительного анализатора, происходящие в результате космического полета. РМЖ. Клиническая офтальмология. 2019; 19 (1): 27–30.Valjah M.A. Changes in the visual analyzer resulting from space flight. RMJ. Clinical ophthalmology. 2019; 19 (1): 27–30 (In Russ.).Wostyn P, De Winne F, Stern C, et al. Potential involvement of the ocular glymphatic system in optic disc edema in astronauts. Aerosp Med Hum Perform. 2020; 91 (12): 975–7. https://doi.org/10.3357/amhp.5670.2020Wostyn P, De Winne F, Stern C, et al. Potential involvement of the ocular glymphatic system in optic disc edema in astronauts. Aerosp Med Hum Perform. 2020; 91 (12): 975–7. https://doi.org/10.3357/amhp.5670.2020Wostyn P, Gibson CR, Mader TH. The odyssey of the ocular and cerebrospinal fluids during a mission to Mars: the “ocular glymphatic system” under pressure. Eye (Lond). 2022; 36 (4): 686–91. https://doi.org/10.1038/s41433-021-01721-9Wostyn P, Gibson CR, Mader TH. The odyssey of the ocular and cerebrospinal fluids during a mission to Mars: the “ocular glymphatic system” under pressure. Eye (Lond). 2022; 36 (4): 686–91. https://doi.org/10.1038/s41433-021-01721-9Малюгин Б.Э., Колотева М.И., Поздеева Н.А. и др. Влияние искусственной гравитации на изменение периметрических показателей органа зрения. Вестник офтальмологии. 2021; 137 (2): 26–33. https://doi.org/10.17116/oftalma202113702126Malyugin B.E., Koloteva M.I., Pozdeyeva N.A., et al. Effects of artificial gravity on perimetry results. Vestnik oftalmologii. 2021; 137 (2): 26–33 (In Russ.). https://doi.org/10.17116/oftalma202113702126Vahdani K, Rose GE. Chorioretinal folds in thyroid eye disease. Ophthalmology. 2019; 126 (8): 1106. https://doi.org/10.1016/j.ophtha.2019.04.045Vahdani K, Rose GE. Chorioretinal folds in thyroid eye disease. Ophthalmology. 2019; 126 (8): 1106. https://doi.org/10.1016/j.ophtha.2019.04.045Corvi F, Capuano V, Benatti L, et al. Atypical presentation of chorioretinal folds-related maculopathy. Optom Vis Sci. 2016; 93 (10): 1304–14. https://doi.org/10.1097/opx.0000000000000953Corvi F, Capuano V, Benatti L, et al. Atypical presentation of chorioretinal folds-related maculopathy. Optom Vis Sci. 2016; 93 (10): 1304–14. https://doi.org/10.1097/opx.0000000000000953Singh G, Guthoff R, Foster CS. Observations on long-term follow-up of posterior scleritis. Am J Ophthalmol. 1986; 101 (5): 570–5. https://doi.org/10.1016/0002-9394(86)90947-5Singh G, Guthoff R, Foster CS. Observations on long-term follow-up of posterior scleritis. Am J Ophthalmol. 1986; 101 (5): 570–5. https://doi.org/10.1016/0002-9394(86)90947-5Чехова Т.А. Задний склерит. Клинический случай. Современные технологии в офтальмологии. 2020; 35 (4): 204–5. https://doi.org/10.25276/2312-4911-2020-4-204-205Chehova T.A. Posterior scleritis. Clinical case. Modern technologies in ophthalmology. 2020; 35 (4): 204–5 (In Russ.). https://doi.org/10.25276/2312-4911-2020-4-204-205Nichani P, Micieli JA. Retinal manifestations of idiopathic intracranial hypertension. Ophthalmol Retina. 2021; 5 (5): 429–37. https://doi.org/10.1016/j.oret.2020.08.016Nichani P, Micieli JA. Retinal manifestations of idiopathic intracranial hypertension. Ophthalmol Retina. 2021; 5 (5): 429–37. https://doi.org/10.1016/j.oret.2020.08.016Musetti D, Nicolò M, Bagnis A, Traverso CE. Chorioretinal folds: associated disorders and a related maculopathy. Am J Ophthalmol. 2014; 158 (2): 409. https://doi.org/10.1016/j.ajo.2014.05.005Musetti D, Nicolò M, Bagnis A, Traverso CE. Chorioretinal folds: associated disorders and a related maculopathy. Am J Ophthalmol. 2014; 158 (2): 409. https://doi.org/10.1016/j.ajo.2014.05.005

The authors declare that there are no conflicts of interest present.