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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">helmholtzeyeinstitute</journal-id><journal-title-group><journal-title xml:lang="ru">Российский офтальмологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Ophthalmological Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0076</issn><issn pub-type="epub">2587-5760</issn><publisher><publisher-name>Real time Publishers</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21516/2072-0076-2024-17-2-19-24</article-id><article-id custom-type="elpub" pub-id-type="custom">helmholtzeyeinstitute-1484</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Толщина перипапиллярного слоя нервных волокон сетчатки у пациентов с миопией, обследованных в промышленной больнице Индии с помощью спектральной оптической когерентной томографии</article-title><trans-title-group xml:lang="en"><trans-title>An assessment of the thickness of the retinal nerve fiber layer around the optic disc using spectral domain optical coherence tomography in myopia patients at an industrial hospital in India</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-6390-9728</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Патель</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Patel</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анамика Патель — консультант, отделение офтальмологии </p><p>Балко Нагар, Корба, Чхаттисгарх, 495684</p></bio><bio xml:lang="en"><p>Anamika Patel — consultant, department of ophthalmology </p><p>Balco Nagar, Korba, Chhattisgarh, 495684</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9961-8991</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чаухан</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Chauhan</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Неха Сингх Чаухан — доцент, отделение офтальмологии </p><p>Праяградж, Уттар-Прадеш, 211012</p></bio><bio xml:lang="en"><p>Neha Singh Chauhan — assistant professor, department of ophthalmology </p><p>United University, Uttar Pradesh, 211012,</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5212-3366</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сунов</surname><given-names>Ч.</given-names></name><name name-style="western" xml:lang="en"><surname>Sunov</surname><given-names>C.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Читра Сунов — заместитель главного врача отделения офтальмологии </p><p>сектор 9, Бхилаи, Чхаттисгарх, 490009</p></bio><bio xml:lang="en"><p>Chitra Sunov — deputy chief medical officer, department of ophthalmology </p><p>Steel Plant, Sector 9, Bhilai, Chhattisgarh, 490009</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9896-047X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сингх</surname><given-names>Анк.</given-names></name><name name-style="western" xml:lang="en"><surname>Singh</surname><given-names>Ank.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анкит Сингх — доцент, специалист по статистике, кафедра общественной медицины </p><p>Праяградж, Уттар-Прадеш, 211012</p></bio><bio xml:lang="en"><p>Ankit Singh — assistant professor cum statistician, department of community medicine </p><p>United University, Uttar Pradesh, 211012,</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8661-2013</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сингх</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Singh</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анудж Сингх — д-р мед. наук, доцент кафедры общественной медицины </p><p>Праяградж, Уттар-Прадеш, 211012</p></bio><bio xml:lang="en"><p>Anuj Singh — MD, assistant professor, department of community medicine </p><p>United University, Uttar Pradesh, 211012,</p></bio><email xlink:type="simple">kshatriyanuj@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Больница BALCO</institution><country>Индия</country></aff><aff xml:lang="en"><institution>BALCO Hospital</institution><country>India</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Объединенный институт медицинских наук</institution><country>Индия</country></aff><aff xml:lang="en"><institution>United Institute of Medical Sciences</institution><country>India</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Больница и исследовательский центр Джавахарлала Неру</institution><country>Индия</country></aff><aff xml:lang="en"><institution>Jawaharlal Nehru Hospital and Research Center</institution><country>India</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>27</day><month>06</month><year>2024</year></pub-date><volume>17</volume><issue>2</issue><fpage>19</fpage><lpage>24</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Патель А., Чаухан Н.С., Сунов Ч., Сингх А., Сингх А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Патель А., Чаухан Н.С., Сунов Ч., Сингх А., Сингх А.</copyright-holder><copyright-holder xml:lang="en">Patel A., Chauhan N.S., Sunov C., Singh A., Singh A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://roj.igb.ru/jour/article/view/1484">https://roj.igb.ru/jour/article/view/1484</self-uri><abstract><p>По всему миру наблюдается эпидемический рост заболеваемости близорукостью с патологическими изменениями глаз миопического генеза. Истончение слоя нервных волокон сетчатки (СНВС) ассоциировано с глаукомным поражением, но остается неясным, меняется ли толщина СНВС в зависимости от рефракционного статуса глаза. В связи с этим важно выяснить, существует ли какая-либо корреляция между толщиной СНВС и аксиальной длиной/аномалией рефракции при близорукости. Цель работы — оценить толщину перипапиллярного слоя СНВС с помощью спектральной оптической когерентной томографии (SD-ОКТ) и определить корреляцию между длиной передне-задней оси (ПЗО) глаза и толщиной перипапиллярного СНВС у пациентов с миопией различной степени. Материал и методы. Перипапиллярную толщину СНВС измеряли методом SD-ОКТ у 100 пациентов (200 глаз) с миопией слабой, средней и высокой степени (в среднем -3,58 ± 2,45 дптр) в возрасте от 15 до 40 лет и оценивали корреляцию ее значений с длиной ПЗО. Результаты. Средняя толщина СНВС на 360° (mean ± SD) составила 92,25 ± 10,04 мкм. В группе слабой миопии величина этого показателя была 98,82 ± 6,67 мкм, в группе миопии средней степени — 89,28 ± 5,23 мкм, в группе высокой миопии — 78,54 ± 7,32 мкм. Средняя толщина СНВС на 360° у пациентов с ПЗО &lt; 24 мм составила 100,06 ± 5,92 мкм, у пациентов с ПЗО от 24 до 26 мм — 89,48 ± 4,59 мкм, а у пациентов с ПЗО &gt; 26 мм — 78,2 ± 6,77 мкм. Выявлена значительная связь между уменьшением средней толщины СНВС на 360° с увеличением степени миопии и ПЗО (p &lt; 0,0001). Заключение. Толщина СНВС уменьшается с увеличением аномалии рефракции и увеличением ПЗО близоруких глаз. Степень миопии может по-разному влиять на толщину СНВС.</p></abstract><trans-abstract xml:lang="en"><p>Myopia is rising as a silent epidemic across the globe with marked ocular morbidity and pathological changes. The retinal nerve fiber layer (RNFL) thinning is indicative of glaucomatous damage; it remains uncertain whether RNFL thickness would vary with the refractive status of the eye. It is therefore important to investigate whether any correlation exists between RNFL measurements and axial length/refractive error in myopia. Purpose. To assess the peripapillary RNFL thickness by spectral domain optical coherence tomography (SD-OCT) and to determine the correlation between axial length and peripapillary RNFL thickness in myopia patients. Material and methods. A total of 100 patients (200 eyes) with low, moderate and high myopia (ave -3.58 ± 2.45 D) aged 15 to 40 years were examined to assess the peripapillary RNFL thickness by SD-OCT and to determine the correlation between axial length (AL) and peripapillary RNFL thickness myopia patients. Results. Average 360-degree RNFL thickness (mean ± SD) was 92.25 ± 10.04 μm. In the low myopic group this parameter was 98.82 ± 6.67 μm, in the moderate myopic group — 89.28±5.23 μm, and in the high myopic group — 78.54 ± 7.32 μm. The average 360-degree mean RNFL thickness in patients with AL &lt; 24 mm was 100.06 ± 5.92 μm, in patients with AL between 24–26 mm — 89.48 ± 4.59 μm, and in patients with AL &gt; 26 mm — 78.2 ± 6.77 μm. There was significant association between thinning of the average 360-degree RNFL thickness with increasing degree of myopia and AL (p &lt; 0.0001). Conclusion. The study shows RNFL thickness decreases with increase in refractive error and increase in axial length of myopic eyes. The degree of myopia may affect the RNFL thickness differently.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>миопия</kwd><kwd>слой нервных волокон сетчатки</kwd><kwd>спектральная оптическая когерентная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>myopia</kwd><kwd>retinal nerve fiber layer</kwd><kwd>spectral domain optical coherence tomography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Wong TY, Foster PJ, Hee J, et al. Prevalence and risk factors for refractive errors in adult Chinese in Singapore. Invest Ophthalmol Vis Sci. 2000 Aug; 41 (9): 2486–94. PMID: 10937558</mixed-citation><mixed-citation xml:lang="en">Wong TY, Foster PJ, Hee J, et al. Prevalence and risk factors for refractive errors in adult Chinese in Singapore. Invest Ophthalmol Vis Sci. 2000 Aug; 41 (9): 2486–94. 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