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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">helmholtzeyeinstitute</journal-id><journal-title-group><journal-title xml:lang="ru">Российский офтальмологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Ophthalmological Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0076</issn><issn pub-type="epub">2587-5760</issn><publisher><publisher-name>Real time Publishers</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21516/2072-0076-2024-17-3-108-112</article-id><article-id custom-type="elpub" pub-id-type="custom">helmholtzeyeinstitute-1558</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Многогранность использования ботокса в страбизмологии</article-title><trans-title-group xml:lang="en"><trans-title>The versatility of botox use in strabismology</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5958-9604</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гладышева</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gladysheva</surname><given-names>G. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гладышева Галина Владимировна — врач-офтальмолог 3-го офтальмологического отделения.</p><p>ул. Колхидская, д. 10, Новосибирск, 630096</p></bio><bio xml:lang="en"><p>Galina V. Gladysheva — ophthalmologist of the 3rd ophthalmology department.</p><p>10, Kolkhidskaya St., Novosibirsk, 630096</p></bio><email xlink:type="simple">g.v.gladysheva@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5120-8360</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Плисов</surname><given-names>И. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Plisov</surname><given-names>I. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Плисов Игорь Леонидович — д-р мед. наук, заведующий 3-м офтальмологическим отделением.</p><p>ул. Колхидская, д. 10, Новосибирск, 630096</p></bio><bio xml:lang="en"><p>Igor L. Plisov — Dr. of Med. Sci., head of the 3rd ophthalmology department.</p><p>10, Kolkhidskaya St., Novosibirsk, 630096</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3096-0024</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анциферова</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Antsiferova</surname><given-names>N. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анциферова Наталья Геннадьевна — канд. мед. наук, врач-офтальмолог 3-го офтальмологического отделения.</p><p>ул. Колхидская, д. 10, Новосибирск, 630096</p></bio><bio xml:lang="en"><p>Natalya G. Antsiferova — Cand. of Med. Sci., ophthalmologist of the 3rd ophthalmology department.</p><p>10, Kolkhidskaya St., Novosibirsk, 630096</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5596-0805</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пущина</surname><given-names>В. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Pushchina</surname><given-names>V. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пущина Варвара Борисовна — врач-офтальмолог 3-го офтальмологического отделения.</p><p>ул. Колхидская, д. 10, Новосибирск, 630096</p></bio><bio xml:lang="en"><p>Varvara B. Pushchina — ophthalmologist of the 3rd ophthalmology department.</p><p>10, Kolkhidskaya St., Novosibirsk, 630096</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1449-5118</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мамулат</surname><given-names>Д. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Mamulat</surname><given-names>D. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мамулат Дарья Римовна — врач-офтальмолог 3-го офтальмологического отделения.</p><p>ул. Колхидская, д. 10, Новосибирск, 630096</p></bio><bio xml:lang="en"><p>Darya R. Mamulat — ophthalmologist of the 3rd ophthalmology department.</p><p>10, Kolkhidskaya St., Novosibirsk, 630096</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАУ НМИЦ «МНТК “Микрохирургия глаза” им. акад. С.Н. Федорова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S. Fedorov Eye Microsurgery Clinic</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>02</day><month>10</month><year>2024</year></pub-date><volume>17</volume><issue>3</issue><fpage>108</fpage><lpage>112</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гладышева Г.В., Плисов И.Л., Анциферова Н.Г., Пущина В.Б., Мамулат Д.Р., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Гладышева Г.В., Плисов И.Л., Анциферова Н.Г., Пущина В.Б., Мамулат Д.Р.</copyright-holder><copyright-holder xml:lang="en">Gladysheva G.V., Plisov I.L., Antsiferova N.G., Pushchina V.B., Mamulat D.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://roj.igb.ru/jour/article/view/1558">https://roj.igb.ru/jour/article/view/1558</self-uri><abstract><p>По мере развития страбизмологии все большую актуальность приобретают вопросы, связанные с применением ботокса при различной глазодвигательной патологии. Анализ литературы показывает, что сведения об эффективности ботокса разноречивы и, как правило, основаны только на краткосрочных результатах. В обзоре представлены данные, касающиеся сравнительной эффективности ботулинического токсина и традиционных хирургических вмешательств при лечении различных заболеваний глазодвигательной системы. Приведены показания к данной терапии, способы и дозы ее применения, осложнения. Обобщенные современные данные о функциональных особенностях возникновения различной патологии в страбизмологии позволяют оценить возможности оптимизации подходов к лечению косоглазия при помощи ботулинического токсина типа А. Для поиска, отбора и обобщения данных в источниках литературы, опубликованных в 1973–2022 гг., использовались базы Google Scholar, PubMed, eLibrary.</p></abstract><trans-abstract xml:lang="en"><p>With the development of strabismology, the issues of using Botox in various eye movement pathologies are gaining relevance. The literature analysis shows that the data concerning the effectiveness of Botox are ambivalent and as a rule, are based on short-term results. The review presents the data on the efficiency of the botulinum toxin in the treatment of various oculomotor system diseases in comparison with traditional surgical interventions. Indications for such therapy, application techniques, doses and complications are discussed. The generalized modern data on the functional features of the onset of various pathologies in strabismology help assess the potentials of optimizing strabismus treatment with type A botulinum toxin. To search for the data published between 1973 and 2022, select and summarize them we used Google Scholar, PubMed and eLibrary databases.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ботокс</kwd><kwd>косоглазие</kwd><kwd>экстраокулярные мышцы</kwd><kwd>хемоденервация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>botox</kwd><kwd>strabismus</kwd><kwd>extraocular muscles</kwd><kwd>chemodenervation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Scott A.B., Rosenbaum A., Collins C.C. Pharmacologic weakening of extraocular muscles. Invest. Ophthalmol. 1973; 12 (12): 924–7. PMID: 4203467.</mixed-citation><mixed-citation xml:lang="en">Scott A.B., Rosenbaum A., Collins C.C. Pharmacologic weakening of extraocular muscles. Invest. Ophthalmol. 1973; 12 (12): 924–7. 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