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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">helmholtzeyeinstitute</journal-id><journal-title-group><journal-title xml:lang="ru">Российский офтальмологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Ophthalmological Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0076</issn><issn pub-type="epub">2587-5760</issn><publisher><publisher-name>Real time Publishers</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21516/2072-0076-2025-18-1-24-29</article-id><article-id custom-type="elpub" pub-id-type="custom">helmholtzeyeinstitute-1711</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Анализ системных факторов риска ретинальных венозных окклюзий у пациентов молодого возраста</article-title><trans-title-group xml:lang="en"><trans-title>Analysis of systemic risk factors in young patients with retinal vein occlusion</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7311-0954</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галимова</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Galimova</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галимова Айсылу Булатовна — канд. мед. наук, заведующая отделением офтальмологии № 2.</p><p>ул. Рихарда Зорге, д. 67, корп. 1, Уфа, Республика Башкортостан, 450075</p></bio><bio xml:lang="en"><p>Aysylu B. Galimova — Cand. of Med. Sci., head of ophthalmological department # 2.</p><p>67, k1, Richard Sorge St., Ufa, Bashkortostan, 450075</p></bio><email xlink:type="simple">aible@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1610-108X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галимова</surname><given-names>В. У.</given-names></name><name name-style="western" xml:lang="en"><surname>Galimova</surname><given-names>V. U.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галимова Венера Узбековна — д-р мед. наук, профессор, профессор кафедры офтальмологии.</p><p>ул. Рихарда Зорге, д. 67, корп. 1, Уфа, Республика Башкортостан, 450075</p></bio><bio xml:lang="en"><p>Venera U. Galimova — Dr. of Med. Sci., professor, professor of chair of ophthalmology.</p><p>67, k1, Richard Sorge St., Ufa, Bashkortostan, 450075</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава России (Всероссийский центр глазной и пластической хирургии)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical University (Russian Centre for Eye and Plastic Surgery)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>26</day><month>03</month><year>2025</year></pub-date><volume>18</volume><issue>1</issue><fpage>24</fpage><lpage>29</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Галимова А.Б., Галимова В.У., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Галимова А.Б., Галимова В.У.</copyright-holder><copyright-holder xml:lang="en">Galimova A.B., Galimova V.U.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://roj.igb.ru/jour/article/view/1711">https://roj.igb.ru/jour/article/view/1711</self-uri><abstract><p>Цель работы — анализ системных факторов риска ретинальных венозных окклюзий (РВО) у пациентов молодого возраста. Материал и методы. В проспективном исследовании серии случаев приняли участие 23 пациента с РВО в возрасте от 24 до 44 лет. Кроме стандартного офтальмологического обследования всем пациентам определяли уровень артериального давления и индекс массы тела, исследовали содержание глюкозы и общего холестерина в крови. Результаты. У подавляющего большинства пациентов диагностирована окклюзия центральной вены сетчатки (73,91%), в четверти случаев (26,09%) — окклюзия ветви центральной вены сетчатки. Модифицируемые факторы риска сердечно-сосудистой патологии установлены у 73,91% пациентов. Наиболее распространенными из них были избыточная масса тела / ожирение (60,27%) и гиперлипидемия (47,37%). Артериальная гипертензия, курение и комбинация гиперлипидемии с избыточной массой тела / ожирением выявлены у 34,78% пациентов. Гипергликемия натощак обнаружена в 9,5% случаев. Из шести пациентов, не имевших традиционных факторов риска, у четверых развитие РВО было ассоциировано с перенесенной новой коронавирусной инфекцией. Одна пациентка страдала наследственной формой тромбофилии (мутация Лейдена). Заключение. Развитие РВО у пациентов молодого возраста в 73,91% случаев ассоциировано с модифицируемыми факторами риска кардиоваскулярной патологии. Воздействие этих факторов и их комбинаций способствует повреждению сосудистой стенки, локальному нарушению гемодинамики и гиперкоагуляции, которые формируют триаду Вирхова, лежащую в основе патогенеза окклюзий вен сетчатки.</p></abstract><trans-abstract xml:lang="en"><p>Purpose: to analyze systemic risk factors of retinal vein occlusion (RVO) in young patients. Material and methods. 23 patients with RVO aged 24–44 were enrolled in a prospective case series study. All patients underwent standard ophthalmological examination, blood pressure measurement, body mass index calculation, fasting glucose and total cholesterol test. Results. Most patients (73.91%) were diagnosed with central RVO, others (26.09%) had branch RVO. Modifiable cardiovascular risk factors were identified in 73.91% of patients. The most prevalent risk factors were overweight/obesity (60.27%) and hyperlipidemia (47.37%). Arterial hypertension, smoking and a combination of hyperlipidemia and overweight/obesity were identified in 34.78% of patients. High fasting glucose level was detected in 9.5% of patients. In four cases out of six without traditional risk factors, RVO was associated with COVID-19. One patient suffered from hereditary thrombophilia (Leiden’s mutation). Conclusion. RVO in young patients is associated with modifiable cardiovascular risk factors in 73.91% of cases. The impact of these risk factors and their combinations leads to vessels wall damage, local circulatory disturbance and hyperviscosity syndrome comprising a Virchow’s triad that underlies the pathogenesis of RVO.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ретинальная венозная окклюзия</kwd><kwd>окклюзия центральной вены сетчатки</kwd><kwd>факторы риска</kwd><kwd>триада Вирхова</kwd><kwd>новая коронавирусная инфекция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>retinal vein occlusion</kwd><kwd>central retinal vein occlusion</kwd><kwd>risk factors</kwd><kwd>Virchow’s triad</kwd><kwd>COVID-19</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rogers S, McIntosh RL, Cheung N, et al. The prevalence of retinal vein occlusion: pooled data from the United States, Europe, Asia and Australia. 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