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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">helmholtzeyeinstitute</journal-id><journal-title-group><journal-title xml:lang="ru">Российский офтальмологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Ophthalmological Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0076</issn><issn pub-type="epub">2587-5760</issn><publisher><publisher-name>Real time Publishers</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21516/2072-0076-2025-18-1-30-35</article-id><article-id custom-type="elpub" pub-id-type="custom">helmholtzeyeinstitute-1712</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Возможности ультразвукового исследования для оценки биометрических характеристик слезной железы в норме у лиц разного возраста</article-title><trans-title-group xml:lang="en"><trans-title>Possibilities of ultrasound examination for assessing biometric characteristics of the lacrimal gland in normal individuals of different ages</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киселева</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiseleva</surname><given-names>T. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Киселева Татьяна Николаевна — д-р мед. наук, профессор, начальник отдела ультразвуковых исследований.</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Tatiana N. Kiseleva — Dr. of Med. Sci., professor, head of ultrasound department.</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4135-1128</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцев</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaitsev</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зайцев Максим Сергеевич — канд. мед. наук, научный сотрудник отдела ультразвуковых исследований.</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Maxim S. Zaitsev — Cand. of Med. Sci., researcher of ultrasound department.</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><email xlink:type="simple">zaicev1549@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцева</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaitseva</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зайцева Алина Андреевна — врач-офтальмолог взрослого консультативного поликлинического отделения.</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Alina A. Zaitseva — ophthalmologist of the adult out-patient department.</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Луговкина</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lugovkina</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Луговкина Ксения Вадимовна — канд. мед. наук, научный сотрудник отдела ультразвуковых исследований.</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Ksenia V. Lugovkina — Cand. of Med. Sci., researcher of ultrasound department.</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ глазных болезней им. Гельмгольца» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Helmholtz National Medical Research Center of Eye Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>26</day><month>03</month><year>2025</year></pub-date><volume>18</volume><issue>1</issue><fpage>30</fpage><lpage>35</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Киселева Т.Н., Зайцев М.С., Зайцева А.А., Луговкина К.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Киселева Т.Н., Зайцев М.С., Зайцева А.А., Луговкина К.В.</copyright-holder><copyright-holder xml:lang="en">Kiseleva T.N., Zaitsev M.S., Zaitseva A.A., Lugovkina K.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://roj.igb.ru/jour/article/view/1712">https://roj.igb.ru/jour/article/view/1712</self-uri><abstract><p>Цель работы — определить биометрические характеристики пальпебральной и орбитальной частей слезной железы (СЖ) в норме у лиц разного возраста. Материал и методы. Обследовано 120 здоровых лиц (240 глаз), в том числе 60 детей (1-я группа) и 60 взрослых (2-я группа). В зависимости от возраста обследуемые были разделены на подгруппы: 1А — 20 детей в возрасте от 1 до 7 лет, 1Б — 20 детей от 7 до 13 лет, 1В — 20 детей от 13 до 17 лет; 2А — 20 взрослых в возрасте от 18 до 40 лет, 2Б — 20 человек от 40 до 60 лет и 2В —20 человек от 60 до 90 лет. Ультразвуковое исследование СЖ проводилось на многофункциональном приборе с использованием линейного датчика 11–18 МГЦ в режиме В-сканирования при средненизких значениях коэффициента усиления сигнала (GAIN). Результаты. Анализ биометрических показателей СЖ показал, что размеры пальпебральной и орбитальной частей СЖ зависят от возраста. Минимальные размеры СЖ отмечались у детей в 1А-подгруппе. Диаметр и толщина пальпебральной части составили 6,49 ± 0,50 и 2,20 ± 0,13 мм соответственно, в то время как размер орбитальной части — 9,50 ± 0,44 мм. У взрослых наименьшие значения биометрических показателей СЖ установлены во 2А-подгруппе, составившие 8,48 ± 0,50 и 2,2 ± 0,1 мм для пальпебральной части и 13,47 ± 0,48 мм для орбитальной части соответственно. В старшей возрастной подгруппе отмечены наибольшие значения параметров орбитальной части СЖ, средний размер которой составил 16,02 ± 0,15 мм. Заключение. Нормативные показатели размеров СЖ значительно отличаются у взрослых и детей, что необходимо учитывать при обследовании пациентов разного возраста с подозрением на патологические изменения СЖ. Выявленные в результате УЗИ биометрические характеристики СЖ у здоровых лиц могут быть использованы в качестве эхографических критериев для диагностики заболеваний СЖ.</p></abstract><trans-abstract xml:lang="en"><p>The purpose was to determine the biometric characteristics of the palpebral and orbital parts of the lacrimal gland (LG) in normal individuals of different ages. Material and methods. A total of 120 healthy individuals (240 eyes) were examined, including 60 children (group 1) and 60 adults (group 2). Depending on their age, the subjects were divided into subgroups: 1A — 20 children aged 1 to 7 years, 1B — 20 children aged 7 to 13 years, 1B — 20 children aged 13 to 17 years, 2A — 20 adults aged 18 to 40 years, 2B — 20 adults aged 40 to 60 years and 2B — 20 adults aged 60 to 90 years. Ultrasound examination (US) of the LG was performed on a multifunctional device using a linear 11–18 MHz sensor in the B-scan mode at medium-low values of the signal gain (GAIN). Results. Analysis of biometric parameters of the LG showed that the sizes of the palpebral and orbital parts of the LG depend on age. The minimum sizes of the LG were noted in children in subgroup 1A. The diameter and thickness of the palpebral part were 6.49±0.50 mm and 2.20 ± 0.13 mm, respectively, while the size of the orbital part was 9.50 ± 0.44 mm. In adults, the lowest values of biometric parameters of the LG were established in subgroup 2A, amounting to 8.48 ± 0.50 mm and 2.2 ± 0.1 mm for the palpebral part and 13.47 ± 0.48 mm for the orbital part, respectively. In the older age subgroup, the highest values of the parameters of the LG orbital part were noted, the average size of which was 16.02 ± 0.15 mm. Conclusion. The normative parameters of LG sizes differ significantly in adults and children, which must be taken into account when examining patients of different ages with suspected pathological changes in the LG. The biometric characteristics of the LG revealed by ultrasound in healthy individuals can be used as echographic criteria for diagnosing LG diseases.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>слезная железа</kwd><kwd>пальпебральная часть</kwd><kwd>орбитальная часть</kwd><kwd>ультразвуковое исследование</kwd><kwd>биометрические параметры</kwd></kwd-group><kwd-group xml:lang="en"><kwd>lacrimal gland</kwd><kwd>palpebral part</kwd><kwd>orbital part</kwd><kwd>ultrasound examination</kwd><kwd>biometric parameters</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Garg A, Zhang X. Lacrimal gland development: From signaling interactions to regenerative medicine. Dev Dyn. 2017; 246 (12): 970–80. doi: 10.1002/dvdy.24551</mixed-citation><mixed-citation xml:lang="en">Garg A, Zhang X. Lacrimal gland development: From signaling interactions to regenerative medicine. 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