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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">helmholtzeyeinstitute</journal-id><journal-title-group><journal-title xml:lang="ru">Российский офтальмологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Ophthalmological Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0076</issn><issn pub-type="epub">2587-5760</issn><publisher><publisher-name>Real time Publishers</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21516/2072-0076-2018-11-4-29-35</article-id><article-id custom-type="elpub" pub-id-type="custom">helmholtzeyeinstitute-190</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Алгоритм ведения хирургических больных с острым некрозом сетчатки</article-title><trans-title-group xml:lang="en"><trans-title>An algorithm for managing surgical patients with acute retinal necrosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нероев</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Neroev</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>член-корр. РАН, д-р мед. наук, профессор, директор</p><p>105062, Москва, ул. Садовая-Черногрязская, д. 14/19</p></bio><bio xml:lang="en"><p>Corresponding member of RAS, Dr. Med. Sci., Professor, director</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Илюхин</surname><given-names>П. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ilyukhin</surname><given-names>P. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, научный сотрудник отдела патологии сетчатки и зрительного нерва</p><p> 105062, Москва, ул. Садовая-Черногрязская, д. 14/19</p></bio><bio xml:lang="en"><p>Cand. Med. Sci., research associate, department of pathology of the retina and optic nerve</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Танковский</surname><given-names>В. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Tankovsky</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, старший научный сотрудник отдела патологии сетчатки и зрительного нерва, доцент кафедры непрерывного медицинского образования</p><p>105062, Москва, ул. Садовая-Черногрязская, д. 14/19</p></bio><bio xml:lang="en"><p>Dr. Med. Sci., senior researcher, department of pathology of the retina and optic nerve, associate professor, continuous medical education chair</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федотов</surname><given-names>Р. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedotov</surname><given-names>R. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант отдела патологии сетчатки и зрительного нерва</p><p>105062, Москва, ул. Садовая-Черногрязская, д. 14/19</p></bio><bio xml:lang="en"><p>PhD student, department of pathology of the retina and optic nerve, ophthalmologist</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062, Russia</p></bio><email xlink:type="simple">fedot88r@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Московский НИИ глазных болезней им. Гельмгольца»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Helmholtz Research Institute of Eye Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>10</day><month>12</month><year>2018</year></pub-date><volume>11</volume><issue>4</issue><fpage>29</fpage><lpage>35</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Нероев В.В., Илюхин П.А., Танковский В.Э., Федотов Р.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Нероев В.В., Илюхин П.А., Танковский В.Э., Федотов Р.А.</copyright-holder><copyright-holder xml:lang="en">Neroev V.V., Ilyukhin P.A., Tankovsky V.E., Fedotov R.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://roj.igb.ru/jour/article/view/190">https://roj.igb.ru/jour/article/view/190</self-uri><abstract><p>Цель работы — повысить эффективность хирургического лечения и разработать алгоритм ведения хирургических больных с последствиями острого некроза сетчатки (ОНС).</p><sec><title>Материал и методы</title><p>Материал и методы. В исследование включены 35 пациентов (42 глаза) в возрасте 18–74 лет с ОНС, которым выполнена микроинвазивная (23 Ga) витрэктомия с мембранопилингом, эндолазерной коагуляцией сетчатки и эндотампонадой витреальной полости силиконовым маслом. Прооперированные глаза разделены на 2 группы. В основную группу (n = 17) включены глаза с клинической картиной фиброза стекловидного тела без отслойки сетчатки (n = 10) и отслойкой сетчатки без выраженного фиброза стекловидного тела (n = 7). В группу сравнения (n = 25) включены глаза, в которых на момент оперативного лечения имелась отслойка сетчатки и фиброз стекловидного тела. Острота зрения до операции была в пределах от неправильной светопроекции до 0,15 с коррекцией.</p></sec><sec><title>Результаты</title><p>Результаты. Стойкий анатомо-оптический результат достигнут во всех случаях. Полное прилегание отслоенной сетчатки достигнуто в 94,1 %, что обусловлено проведением хирургического лечения при отсутствии в большинстве случаев выраженных стадий пролиферативной витреоретинопатии. В основной группе повышение остроты зрения отмечено во всех случаях, при этом острота зрения от 0,1 до 0,3 достигнута в 53 % случаев, 0,3 и выше — в 47 %, что обусловлено преобладанием периферической зоны некротического поражения, а также меньшей частотой развития макулярного отека и оптической нейропатии. В группе сравнения повышение остроты зрения наблюдалось лишь в 56 % случаев, при этом острота зрения 0,1 и выше получена только в 24 % глаз, выявлена также высокая частота (72 %) распространения некроза до заднего полюса глаза с необратимым поражением зрительного нерва и макулярной области.</p></sec><sec><title>Заключение</title><p>Заключение. Активное динамическое наблюдение за больными, перенесшими ОНС, позволяет обнаружить изменения, требующие хирургического лечения, что дает возможность достигать более высоких функциональных и анатомических результатов, а также избежать инвалидизации пациентов. Оперативное лечение целесообразно проводить до формирования отслойки сетчатки при выраженном тракционном синдроме с разрывами сетчатки или без них. Предложен алгоритм ведения хирургических больных в зависимости от клинических проявлений последствий ОНС.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose. To increase the efficiency of surgical treatment and develop an algorithm for managing patients with the consequences of acute retinal necrosis (ARN).</p></sec><sec><title>Material and methods</title><p>Material and methods. The study included 35 patients (42 eyes) aged 18 to 74 with acute retinal necrosis. All patients underwent a microinvasive (23 Ga) vitrectomy with membrane peel, endolaser coagulation of the retina and endotamponade of the vitreal cavity with silicone oil. The operated eyes were divided into 2 groups. The main group consisted of 17 eyes with a clinical picture of fibrosis of the vitreous without retinal detachment (10 eyes) and retinal detachment without pronounced fibrosis of the vitreous (7 eyes). The comparison group included 25 eyes which had retinal detachment and fibrosis of the vitreous at the time of surgery. The visual acuity varied between incorrect light projection and 0.15 with correction.</p></sec><sec><title>Results</title><p>Results. A stable anatomical and optical result was achieved in all cases. Complete adhesion of the detached retina was achieved in 94.1 %, which is explained by the fact that surgical treatment was in most cases performed in the absence of pronounced stages of proliferative vitreoretinopaty. In all cases of the main group, an increase in visual acuity was noted. In 53 % of cases, visual acuity achieved 0.1 to 0.3 and in the remaining 47 % it was 0.3 % or above. This can be accounted for by the prevalence of peripheral necrotic lesions, as well as a lower incidence of macular edema and optic neuropathy. However, in the comparison group, an increase in visual acuity was only observed in 56 % cases, with visual acuity reaching 0.1 or higher only in 24 % of the eyes. A high frequency (72 %) of necrosis expansion to the posterior eye pole with an irreversible damage to the optic nerve and the macular region was revealed.</p></sec><sec><title>Conclusion</title><p>Conclusion. Active dynamic observation of patients with ARN helps detect changes requiring surgical treatment, which leads to higher functional and anatomical outcomes, as well helps avoid the disability of the patients. Surgical treatment prior to the formation of retinal detachment in severe traction syndrome with or without retinal tears is advisable. An algorithm was proposed for managing surgical patients, depending on the clinical manifestations of ARN effects.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>офтальмология</kwd><kwd>офтальмохирургия</kwd><kwd>увеит</kwd><kwd>острый некроз сетчатки</kwd><kwd>ретинит</kwd><kwd>витрэктомия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ophthalmic surgery</kwd><kwd>uveitis</kwd><kwd>acute retinal necrosis</kwd><kwd>retinitis</kwd><kwd>vitrectomy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Holland G.N. Standard diagnostic criteria for the acute retinal necrosis syndrome. Executive Committee of the American Uveitis Society. Am. J. 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