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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">helmholtzeyeinstitute</journal-id><journal-title-group><journal-title xml:lang="ru">Российский офтальмологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Ophthalmological Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0076</issn><issn pub-type="epub">2587-5760</issn><publisher><publisher-name>Real time Publishers</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21516/2072-0076-2018-11-4-64-67</article-id><article-id custom-type="elpub" pub-id-type="custom">helmholtzeyeinstitute-195</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭКСПЕРИМЕНТАЛЬНО-ЛАБОРАТОРНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERIMENTAL AND LABORATORY STUDIES</subject></subj-group></article-categories><title-group><article-title>Морфологические исследования кадаверной склеры после непроникающей Nd: YAG-лазерной склеротомии</article-title><trans-title-group xml:lang="en"><trans-title>Morphological studies of the cadaveric sclera after nonpenetrating sclerotomy by ND: YAG laser</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синеок</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Sineok</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, научный сотрудник, врач-офтальмолог офтальмологического микрохирургического отделения</p><p>443099, Самара, ул. Чапаевская, д. 89</p><p>443068, Самара, ул. Ново-Садовая, д. 158</p><p> </p></bio><bio xml:lang="en"><p>Cand. Med. Sci., ophthalmologist of 4nd surgical department</p><p>89, Chapayevskaya St., Samara, 443099, Russia</p><p>158, Novo-Sadovaja St., Samara, 443068, Russia</p></bio><email xlink:type="simple">sineokae@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Золотарев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zolotarev</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, профессор, директор, заведующий кафедрой офтальмологии,главный врач</p><p>443099, Самара, ул. Чапаевская, д. 89</p><p>443068, Самара, ул. Ново-Садовая, д. 158</p></bio><bio xml:lang="en"><p>Dr. Med. Sci., Professor, director, head of the ophthalmological department, chief doctor</p><p>89, Chapayevskaya St., Samara, 443099, Russia</p><p>158, Novo-Sadovaja St., Samara, 443068, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаева</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaeva</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>заведующая патогистологической лабораторией</p><p>443099, Самара, ул. Чапаевская, д. 89</p><p>443068, Самара, ул. Ново-Садовая, д. 158</p></bio><bio xml:lang="en"><p>head of the pathohistological laboratory</p><p>89, Chapayevskaya St., Samara, 443099, Russia</p><p>158, Novo-Sadovaja St., Samara, 443068, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО СамГМУ, научно-исследовательский институт глазных болезней&#13;
ГБУЗ «Самарская областная клиническая офтальмологическая больница им. Т.И. Ерошевского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Medical University, Research Institute of Eye Diseases&#13;
Samara T.I. Eroshevskiy regional clinical ophthalmological hospital</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>11</day><month>12</month><year>2018</year></pub-date><volume>11</volume><issue>4</issue><fpage>64</fpage><lpage>67</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Синеок А.Е., Золотарев А.В., Николаева Г.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Синеок А.Е., Золотарев А.В., Николаева Г.А.</copyright-holder><copyright-holder xml:lang="en">Sineok A.E., Zolotarev A.V., Nikolaeva G.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://roj.igb.ru/jour/article/view/195">https://roj.igb.ru/jour/article/view/195</self-uri><abstract><p>Цель — выявить изменения морфологического строения склеры кадаверных человеческих глаз после излучения Nd: YAG-лазера.</p><sec><title>Материал и методы</title><p>Материал и методы. Лазерные импульсы Nd: YAG (Lumenis) мощностью от 7,0–7,4 мВт (длительность импульса — 4 нс, длина волны — 1064 нм) подавались на склеру изолированного глазного яблока на расстоянии от 4 до 8 мм от лимба. Применяли 3 типа излучения: фокусировали один ряд одиночных импульсов, затем ряд из трехкратных импульсов и ряд из шестикратных импульсов.</p></sec><sec><title>Результаты</title><p>Результаты. В случае одиночных импульсов выявлены незначительные дефекты поверхностных слоев склеры. При трехкратном импульсе дефект передних слоев склеры достигал 15 % толщины склеры, а при шестикратном импульсном излучении — до 30 % ее толщины.</p></sec><sec><title>Заключение</title><p>Заключение. Для получения точечного отверстия в склере недостаточно одиночного импульса Nd: YAG, для значимой глубины надреза склеры необходим как минимум трехкратный импульс, что необходимо учитывать в клинической практике и при оценке результатов воздействия Nd: YAG-лазера на ригидность фиброзной оболочки глаза.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose: to reveal the changes of the morphological structure of cadaveric human sclera after Nd: YAG laser irradiation.</p></sec><sec><title>Material and methods</title><p>Material and methods. Laser pulses (Nd: YAG) (Lumenis) (power 7.0–7.4 mW, pulse duration 4 ns, wavelength 1064 nm) were applied to the sclera of an isolated eyeball at a distance of 4 to 8 mm from the limbus. Three irradiation types were used: one series of single pulses, a series of triple pulses, and a series of six pulses.</p></sec><sec><title>Results</title><p>Results. Incisions created with single pulses showed insignificant surface defects of the sclera. In triple pulses, the defect of the anterior layers of the sclera capture affected 15 % of the scleral thickness, and in six pulses the defect reached 30 % of the scleral thickness.</p></sec><sec><title>Conclusions</title><p>Conclusions. To achieve a punctate hole in the sclera, a single Nd: YAG pulse is insufficient. To obtain a significant depth of scleral incision at least a triple pulse is needed, which must be taken into account in clinical practice as well as in assessing the results of Nd: YAG laser impact on the rigidity of the sclera.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>склера</kwd><kwd>ригидность глаза</kwd><kwd>склеротомия</kwd><kwd>Nd: YAG-лазер</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sclera</kwd><kwd>ocular rigidity</kwd><kwd>sclerotomy</kwd><kwd>Nd: YAG-laser</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Аветисов С.Э., Большунов А.В., Хомчик О.В. и др. Лазер-индуцированное повышение гидропроницаемости склеры в лечении резистентных форм открытоугольной глаукомы. Национальный журнал глаукома. 2015; 14 (2): 5–13.</mixed-citation><mixed-citation xml:lang="en">Avetisov S.E., Bol'shunov A.V., Khomchik O.V., et al. Laser-induced increase in scleral hydropermeability in the treatment of resistant forms of open-angle glaucoma. Natsional'nyy zhurnal glaukoma. 2015; 14 (2): 5–13 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Большунов А.В., Хомчик О.В., Соболь Э.Н. и др. Способ лечения резистентных форм открытоугольной глаукомы. Патент РФ № 2463029; 2012.</mixed-citation><mixed-citation xml:lang="en">Bol'shunov A.V., Khomchik O.V., Sobol' E.N., et al. The method of treatment of resistant forms of open-angle glaucoma. Patent RF № 2463029; 2012. (Byull. 28) (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Klink T., Schlunck G., Lieb W., Klink J., Grehn F. CО2, excimer and erbium: YAG laser in deep sclerectomy. Ophthalmologica. 2008; 222 (2): 74–80. https://doi.org/10.1159/000112622</mixed-citation><mixed-citation xml:lang="en">Klink T., Schlunck G., Lieb W., Klink J., Grehn F. CO2, excimer and erbium: YAG laser in deep sclerectomy. Ophthalmologica. 2008; 222 (2): 74–80. https://doi.org/10.1159/000112622</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Jacobi P.C., Dietlein T.S., Krieglstein G.K. Prospective study of ab externo erbium:YAG laser sclerostomy in humans. Am. J. Ophthalmol. 1997; 123 (4): 478–86. http://dx.doi.org/10.1016/S0002-9394(14)70173-4</mixed-citation><mixed-citation xml:lang="en">Jacobi P.C., Dietlein T.S., Krieglstein G.K. Prospective study of ab externo erbium:YAG laser sclerostomy in humans. Am. J. Ophthalmol. 1997; 123 (4): 478–86. http://dx.doi.org/10.1016/S0002-9394(14)70173-4</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Iwach A.G., Hoskins H.D. Jr., Drake M.V., Dickens C.J. Subconjunctival THC:YAG (holmium) laser thermal sclerostomy ab externo. A one-year report. Ophthalmology. 1993; 100 (3): 356–65. http://dx.doi.org/10.1016/S0161-6420(93)31641-6</mixed-citation><mixed-citation xml:lang="en">Iwach A.G., Hoskins H.D.Jr., Drake M.V., Dickens C.J. Subconjunctival THC: YAG (holmium) laser thermal sclerostomy ab externo. A one-year report. Ophthalmology. 1993; 100 (3): 356–65. http://dx.doi.org/10.1016/S0161-6420(93)31641-6</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Latina M.A., Rankin G.A. Internal and transconjunctival neodymium:YAG laser revision of late failing filters. Ophthalmology. 1991 98 (2): 215–21. http://dx.doi.org/10.1016/S0161-6420(91)32314-5</mixed-citation><mixed-citation xml:lang="en">Latina M.A., Rankin G.A. Internal and transconjunctival neodymium: YAG laser revision of late failing filters. Ophthalmology. 1991; 98 (2): 215–21. http://dx.doi.org/10.1016/S0161-420(91)32314-5</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Weber P.A., Jones J.H., Kapetansky F. Neodymium: YAG transconjunctival laser revision of late-failing filtering blebs. Ophthalmology. 1999; 106 (10): 2023–6. doi: 10.1016/S0161-6420(99)90418-9</mixed-citation><mixed-citation xml:lang="en">Weber P.A., Jones J.H., Kapetansky F. Neodymium: YAG transconjunctival laser revision of late-failing filtering blebs. Ophthalmology. 1999; 106 (10): 2023–6. doi: 10.1016/S0161-6420(99)90418-9</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Шахно Е.А. Физические основы применения лазеров в медицине. Санкт-Петербург: НИУ ИТМО; 2012.</mixed-citation><mixed-citation xml:lang="en">Shakhno E.A. Physical principles of the use of lasers in medicine. Sankt Petersburg: NIU ITMO; 2012 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Рябцева А.А., Сергушев С.Г., Хомякова Е.Н., Кошиц И.Н. Способ лечения глаукомы. Патент РФ № 2366392; 2009.</mixed-citation><mixed-citation xml:lang="en">Ryabtseva A.A., Sergushev S.G., Khomyakova E.N., Koshits I.N. The method of treatment of glaucoma. Patent RF № 2366392; 2009 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Иомдина Е.Н., Киселева О.А., Назаренко Л.А., Игнатьева Н.Ю., Баграташвили В.Н. Влияние биомеханических свойств корнеосклеральной капсулы глаза на гидродинамику внутриглазной жидкости. Биомедицина. 2012; 3: 25–34.</mixed-citation><mixed-citation xml:lang="en">Iomdina E.N., Kiseleva O.A., Nazarenko L.A., Ignat'eva N.Yu., Bagratashvili V.N. Influence of biomechanical properties of the corneoscleral capsule of the eye on the hydrodynamics of the intraocular fluid. Biomeditsina. 2012; 3: 25–34 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Baum O.I., Sobol E.N., Bolshunov A.V., et al. Microstructural changes in sclera under thermo-mechanical effect of 1.56 μm laser radiation increasing transscleral humor outflow. Lasers Surg Med. 2014; 46 (1): 46–53. doi: 10.1002/lsm.22202</mixed-citation><mixed-citation xml:lang="en">Baum O.I., Sobol E.N., Bolshunov A.V., et al. Microstructural changes in sclera under thermo-mechanical effect of 1.56 μm laser radiation increasing transscleral humor outflow. Lasers Surg Med. 2014; 46 (1): 46–53. doi:10.1002/lsm.22202</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Pallikaris I.G., Kozobolis V.P., Christodoulakis E.V. Erbium: YAG laser deep sclerectomy: an alternative approach to glaucoma surgery. Ophthalmic Surg. Lasers Imaging. 2003; 34 (5): 375–80. https://www.ncbi.nlm.nih.gov/pubmed/14509460</mixed-citation><mixed-citation xml:lang="en">Pallikaris I.G., Kozobolis V.P., Christodoulakis E.V. Erbium: YAG laser deep sclerectomy: an alternative approach to glaucoma surgery. Ophthalmic Surg. Lasers Imaging. 2003; 34 (5): 375–80. https://www.ncbi.nlm.nih.gov/pubmed/14509460</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
