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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">helmholtzeyeinstitute</journal-id><journal-title-group><journal-title xml:lang="ru">Российский офтальмологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Ophthalmological Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0076</issn><issn pub-type="epub">2587-5760</issn><publisher><publisher-name>Real time Publishers</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21516/2072-0076-2026-19-1-38-43</article-id><article-id custom-type="elpub" pub-id-type="custom">helmholtzeyeinstitute-2045</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Влияние индекса массы тела на толщину слоя нервных волокон сетчатки у взрослых</article-title><trans-title-group xml:lang="en"><trans-title>Effect of body mass index on retinal nerve fiber layer thickness in adults</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ахмед</surname><given-names>У.</given-names></name><name name-style="western" xml:lang="en"><surname>Ahmed</surname><given-names>U.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Урва Ахмед — бакалавр, диплом с отличием по специальности «Оптометрия и ортоптика», оптометрист</p><p>Равалпинди, 4600</p></bio><bio xml:lang="en"><p>Urwa Ahmed — B.Sc., Honor Optometry and Orthoptics, Optometrist</p><p>Rawalpindi, 4600</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Насим</surname><given-names>И.</given-names></name><name name-style="western" xml:lang="en"><surname>Nasim</surname><given-names>I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иффат Насим — диплом с отличием бакалавра наук в области оптометрии и ортоптики, оптометрист</p><p>Равалпинди, 4600</p></bio><bio xml:lang="en"><p>Iffat Nasim — B.Sc. Honor Optometry and Orthoptics, Optometrist</p><p>Rawalpindi, 4600</p></bio><email xlink:type="simple">iffatnasim2@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аюб</surname><given-names>Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Ayub</surname><given-names>F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Фариха Аюб — бакалавр в области оптометрии и ортоптики, магистр философии в области оптометрии, преподаватель</p><p>Равалпинди, 4600</p></bio><bio xml:lang="en"><p>Fareeha Ayub — B.Sc Honor Optometry and Orthoptics, M. phill Optometry, Lecturer</p><p>Rawalpindi, 4600</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Азиз</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Aziz</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Амтул Азиз — диплом по офтальмологии и хирургии, бакалавр по медицине, заведующий отделением диагностики</p><p>Равалпинди, 4600</p></bio><bio xml:lang="en"><p>Amtul Aziz — DOMS, MBBS, Head of Diagnostics Department </p><p>Rawalpindi, 4600</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Амджад</surname><given-names>Азка</given-names></name><name name-style="western" xml:lang="en"><surname>Amjad</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Азка Амджад — бакалавр оптометрии и ортоптики, оптометрист </p><p>Равалпинди, 4600</p></bio><bio xml:lang="en"><p>Azka Amjad — B.Sc. Honor Optometry and Orthoptics, Optometrist </p><p>Rawalpindi, 4600</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джавед</surname><given-names>И.</given-names></name><name name-style="western" xml:lang="en"><surname>Javed</surname><given-names>I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Икра Джавед — диплом с отличием бакалавра в области оптометрии и ортоптики, оптометрист</p><p>Равалпинди, 4600</p></bio><bio xml:lang="en"><p>Iqra Javed — B.Sc. Honor Optometry and Orthoptics, Optometrist</p><p>Rawalpindi, 4600</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Пакистанский институт офтальмологии, офтальмологическая больница «Аль-Шифа»</institution><country>Пакистан</country></aff><aff xml:lang="en"><institution>Pakistan Institute of Ophthalmology, Al-Shifa Trust Eye Hospital</institution><country>Pakistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>05</day><month>04</month><year>2026</year></pub-date><volume>19</volume><issue>1</issue><fpage>38</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ахмед У., Насим И., Аюб Ф., Азиз А., Амджад А., Джавед И., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Ахмед У., Насим И., Аюб Ф., Азиз А., Амджад А., Джавед И.</copyright-holder><copyright-holder xml:lang="en">Ahmed U., Nasim I., Ayub F., Aziz A., Amjad A., Javed I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://roj.igb.ru/jour/article/view/2045">https://roj.igb.ru/jour/article/view/2045</self-uri><abstract><p>Цель работы — исследовать межокулярные различия в толщине слоя нервных волокон сетчатки (СНВС), сравнить толщину СНВС у пациентов с разными категориями индекса массы тела (ИМТ) и изучить взаимосвязь между ИМТ и толщиной СНВС.</p><sec><title>Материал и методы</title><p>Материал и методы. В сентябре 2024 г. в офтальмологической больнице Аль-Шифа проведено поперечное исследование с участием 107 человек (46 женщин, 61 мужчина) в возрасте 27,17 ± 6,98 года. Оценивали остроту зрения с помощью таблиц Снеллена, проводили рефрактометрию и биомикроскопию с помощью щелевой лампы. ИМТ рассчитывался и классифицировался на категории: недостаточный вес, нормальный вес, избыточный вес и ожирение. Толщину СНВС измеряли с помощью оптической когерентной томографии (ОКТ) в верхнем, нижнем, носовом и височном квадрантах.</p></sec><sec><title>Результаты</title><p>Результаты. ИМТ значимо различался у мужчин и женщин. У мужчин средняя толщина СНВС составляла 99,23 ± 4,9 мкм, у женщин 99,20 ± 5,33 мкм, при этом самый тонкий слой у тех и у других находился в височном квадранте. У женщин с ожирением толщина СНВС была больше в верхнем квадранте, а у мужчин с ожирением — в нижнем квадранте. Обнаружена значительная положительная корреляция между ИМТ и толщиной СНВС, особенно в верхнем квадранте у женщин с ожирением и в нижнем квадранте у мужчин с ожирением. Выявлены межокулярные различия: толщина СНВС выше в горизонтальных квадрантах (наружном и внутреннем) в правом глазу и в вертикальных (верхнем и нижнем) в левом глазу.</p></sec><sec><title>Заключение</title><p>Заключение. Толщина СНВС значимо зависит от категории ИМТ. При ожирении у мужчин СНВС толще в нижнем квадранте, а у женщин — в верхнем квадранте. Межокулярные различия показывают вариации толщины СНВС в различных квадрантах.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose: to investigate inter-ocular variation in retinal nerve fiber layer (RNFL) thickness, compare RNFL thickness across body mass index (BMI) categories, and examine the relationship between BMI and RNFL thickness.</p></sec><sec><title>Material and methods</title><p>Material and methods. A cross-sectional study was conducted in September 2024 at Al Shifa Trust Eye Hospital with 107 participants (46 females, 61 males) aged 27.17 ± 6.98 yrs. Visual acuity was assessed using Snellen charts, and refraction and slit-lamp bio-microscopic examination was performed. BMI was calculated and classified into underweight, normal, overweight, and obese categories. Optical coherence tomography (OCT) measured RNFL thickness in the superior, inferior, nasal, and temporal quadrants.</p></sec><sec><title>Results</title><p>Results. Statistically significant BMI differences were found between males and females. Males had an average RNFL thickness of 99.23 ± 4.9 μm, with the thinnest RNFL in the temporal quadrant. Females had an average RNFL thickness of 99.20 ± 5.33 μm, with the temporal quadrant also being the thinnest. Obese females had thicker RNFL in the superior quadrant, while obese males had thicker RNFL in the inferior quadrant. A significant positive correlation between BMI and RNFL thickness was found, particularly in the superior quadrant for obese females and the inferior quadrant for obese males. Inter-ocular differences showed thicker horizontal RNFL quadrants in the right eye and thicker vertical quadrants in the left eye.</p></sec><sec><title>Conclusion</title><p>Conclusion. Significant differences in RNFL thickness exist across BMI categories. The inferior quadrant is thicker in obese males, while the superior quadrant is thicker in obese females. Inter-ocular differences show variations in quadrant thickness between the eyes.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>оптическая когерентная томография</kwd><kwd>индекс массы тела</kwd><kwd>нейрон сетчатки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>optical coherence tomography</kwd><kwd>body mass index</kwd><kwd>retinal neuron</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Jonas JB, Dichtl A. Evaluation of the retinal nerve fiber layer. Surv Ophthalmol. 1996 Mar-Apr; 40 (5): 369–78. doi: 10.1016/s0039-6257(96)80065-8</mixed-citation><mixed-citation xml:lang="en">Jonas JB, Dichtl A. Evaluation of the retinal nerve fiber layer. 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