helmholtzeyeinstituteРоссийский офтальмологический журналRussian Ophthalmological Journal2072-00762587-5760Real time Publishers10.21516/2072-0076-2019-12-1-5-9helmholtzeyeinstitute-217Research ArticleКЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯCLINICAL STUDIESЭффективность применения масла сейданы в комплексном лечении эндотелиального герпетического кератитаEffectiveness of Seydana oil in combination treatment of herpetic endothelial keratitisГулиеваМ. Г.GulievaM. G.

канд. мед. наук, врач-офтальмолог

AZ1114, Баку, ул. Джавадхана, 32/15

Cand. Med. Sci., ophthalmologist

32/15, Dzhavadkhan St., Baku, AZ1114, Azerbaijan

minaragamid@gmail.comНациональный центр офтальмологии им. акад. Зарифы Алиевой Минздрава Азербайджанской РеспубликиАзербайджанZarifa Aliyeva National Center of OphthalmologyAzerbaijan20191403201912159Copyright © Гулиева М.Г., 20192019Гулиева М.Г.Gulieva M.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://roj.igb.ru/jour/article/view/217

Цель — исследование эффективности масла сейданы (черного тмина) в комплексном лечении эндотелиального герпетического кератита. Материал и методы. В исследовании принимали участие 68 пациентов, в том числе 38 мужчин и 30 женщин в возрасте от 39 до 73 (в среднем 58,3 ± 8,9) лет. Основная группа — 34 больных (34 глаза) — получала в комплексе с традиционным лечением дополнительно масло сейданы; группа сравнения — 34 больных (34 глаза) — получала только традиционное лечение. Результаты. Резорбция инфильтрации роговицы у больных основной группы завершилась раньше, чем в контрольной (соответственно, 18,43 ± 0,30 и 23,25 ± 0,50 дня; р < 0,05), длительность лечения пациентов основной группы была меньше, чем в контрольной (22,1 ± 0,1 и 25,25 ± 0,30 дня; р < 0,05). Полная эпителизация отмечена в среднем на 19–21-й день лечения (соответственно, 19,6 ± 0,9 и 21,12 ± 0,60 дня; р > 0,05). Достигнутая острота зрения составила, соответственно, 0,51 ± 0,24 и 0,44 ± 0,17 (р > 0,05). Заключение. Основная группа, получавшая дополнительно к  орадиционному лечению масло сейданы, по некоторым параметрам (срок резорбции инфильтрации роговицы и длительность лечения) показала достоверно более высокий лечебный эффект, чем группа сравнения.

Purpose: to study the effectiveness of seydana (black cumin) oil in combined treatment of herpetic endothelial keratitis. Material and methods. The study included 68 patients (68 eyes) with herpetic endothelial keratitis, developed after cataract surgery. 35 men and 33 women aged 39 to 73 (58.3 ± 8.9) years were divided into two equal groups. The main group (34 patients, 34 eyes) received conventional treatment supplemented with black cumin oil, while the comparison group of 34 patients (34 eyes) received conventional treatment alone. Results. Cornea infiltration in the main group resorbed sooner than in the comparison group (18.43 ± 0.3 days and 23.2 ± 0.5 days respectively; p < 0.05). The treatment lasted shorter in the main group compared with the comparison group (22.1 ± 0.1 days vs. 25.2 ± 0.3 days; p < 0.05). Complete epithelialization was averagely noted on the 19th to the 21st day of treatment (respectively, 19.6 ± 0.9 and of 21.12 ± 0.6; p > 0.05). Visual acuity improved to achieve, respectively, 0.51 ± 0.24 and 0.44 ± 0.17 (p > 0.05). Conclusion. The patients who received seydana oil in addition to conventional treatment showed a significantly higher therapeutic effect in some parameters (resorption time of corneal infiltration and duration of treatment) than the comparison group.

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The authors declare that there are no conflicts of interest present.