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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">helmholtzeyeinstitute</journal-id><journal-title-group><journal-title xml:lang="ru">Российский офтальмологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Ophthalmological Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0076</issn><issn pub-type="epub">2587-5760</issn><publisher><publisher-name>Real time Publishers</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21516/2072-0076-2026-19-3-34-41</article-id><article-id custom-type="elpub" pub-id-type="custom">helmholtzeyeinstitute-2219</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Влияние удаления и сохранения внутренней пограничной мембраны на параметры микрососудистого русла и толщину сетчатки в макулярной области после хирургии идиопатического эпиретинального фиброза у пациентов старшей возрастной группы</article-title><trans-title-group xml:lang="en"><trans-title>The effect of removal and preservation of the internal limiting membrane on parameters of the microvascular bed and retinal thickness in the macular area after surgery for idiopathic epiretinal fibrosis in patients of the older age group</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5189-322X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лыскин</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyskin</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Павел Владимирович Лыскин — д-р мед. наук, заведующий отделом витреоретинальной хирургии.</p><p>Бескудниковский бульвар, д. 59а, Москва, 127486</p></bio><bio xml:lang="en"><p>Pavel V. Lyskin — Dr. of Med. Sci., ophthalmologist, vitreoretinal surgery department.</p><p>59а, Beskudnikovsky Blvd., Moscow, 127486</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3334-8754</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чуканин</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chukanin</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Олег Александрович Чуканин — аспирант отдела витреоретинальной хирургии МНТК “Микрохирургия глаза” им. акад. С.Н. Федорова, врач-офтальмолог ГБУЗ Московской области «Королёвская больница».</p><p>Бескудниковский бульвар, д. 59а, Москва, 127486; ул. Циолковского, д. 24, Королёв, Московская область, 141070</p></bio><bio xml:lang="en"><p>Oleg A. Chukanin — PhD student S.N. Fedorov NMRC “MNTK “Eye Microsurgery”, ophthalmologist, vitreoretinal surgery department Moscow Region “Korolevskaya Hospita”.</p><p>59а, Beskudnikovsky Blvd., Moscow, 127486; 24, Tsiolkovsky St., Korolev, Moscow Region, 141070</p></bio><email xlink:type="simple">chucaninoleg@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6719-6878</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макаренко</surname><given-names>И. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarenko</surname><given-names>I. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ирина Романовна Макаренко — канд. мед. наук, заведующая отделением офтальмологии.</p><p>Ул. Циолковского, д. 24, Королёв, Московская область, 141070</p></bio><bio xml:lang="en"><p>Irina R. Makarenko — Cand. of Med. Sci., head, ophthalmological department.</p><p>24, Tsiolkovsky St., Korolev, Moscow Region, 141070</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-5137-7057</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полякова</surname><given-names>Н. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Polyakova</surname><given-names>N. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Надежда Олеговна Полякова — ординатор отдела витреоретинальной хирургии.</p><p>Бескудниковский бульвар, д. 59а, Москва, 127486</p></bio><bio xml:lang="en"><p>Nadezhda O. Polyakova — resident, vitreoretinal surgery department</p><p>59а, Beskudnikovsky Blvd., Moscow, 127486</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАУ НМИЦ «МНТК “Микрохирургия глаза” им. акад. С.Н. Федорова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S.N. Fedorov NMRC “MNTK “Eye Microsurgery”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАУ НМИЦ «МНТК “Микрохирургия глаза” им. акад. С.Н. Федорова» Минздрава России; ГБУЗ Московской области «Королёвская больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S.N. Fedorov NMRC “MNTK “Eye Microsurgery”; Moscow Region “Korolevskaya Hospital”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ Московской области «Королёвская больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Region “Korolevskaya Hospital”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2026</year></pub-date><volume>19</volume><issue>3</issue><fpage>34</fpage><lpage>41</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лыскин П.В., Чуканин О.А., Макаренко И.Р., Полякова Н.О., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Лыскин П.В., Чуканин О.А., Макаренко И.Р., Полякова Н.О.</copyright-holder><copyright-holder xml:lang="en">Lyskin P.V., Chukanin O.A., Makarenko I.R., Polyakova N.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://roj.igb.ru/jour/article/view/2219">https://roj.igb.ru/jour/article/view/2219</self-uri><abstract><p>Цель работы — оценить влияние удаления и сохранения внутренней пограничной мембраны (ВПМ) на плотность микрососудистого русла (в поверхностном и глубоком сосудистых сплетениях сетчатки) и толщину сетчатки в макулярной области у пациентов старшей возрастной группы, прооперированных по поводу идиопатического эпиретинального фиброза (ЭРФ).</p><sec><title>Материал и методы</title><p>Материал и методы. В ретроспективное исследование вошли 103 пациента (103 глаза) в возрасте от 56 до 78 лет (в среднем 67,1 ± 7,8 года), которым проведено хирургическое лечение идиопатического ЭРФ. Пациенты были разделены на 2 группы: основную — где ЭРФ был удален с сохранением ВПМ (67 глаз) и контрольную — где ЭРФ был удален вместе с ВПМ (36 глаз). Оценку плотности сосудов поверхностного сосудистого сплетения (ПСС), глубокого сосудистого сплетения (ГСС) и толщины сетчатки проводили с помощью оптической когерентной томографии с функцией ангиографии. Срок наблюдения за пациентами составил от 6 мес до 3 лет.</p></sec><sec><title>Результаты</title><p>Результаты. При сохранении ВПМ во всех анализируемых областях сетчатки показатели плотности сосудов ПСС и ГСС были сопоставимы с показателями контрольной группы здоровых лиц аналогичного возраста. Толщина сетчатки во всех анализируемых областях статистически не отличалась от толщины сетчатки здоровых людей. При удалении ВМП плотность сосудов ПСС была снижена во всех анализируемых областях сетчатки по сравнению с аналогичными показателями здоровых пациентов. Плотность сосудов ГСС была снижена в фовеальной области по сравнению с данным показателем в группе контроля и осталась неизменной в прочих анализируемых областях. Толщина сетчатки во всех анализируемых областях была снижена относительно толщины сетчатки у здоровых людей старшей возрастной группы.</p></sec><sec><title>Заключение</title><p>Заключение. Сохранение ВПМ после удаления идиопатического ЭРФ не приводит к снижению показателей плотности сосудистого русла и уменьшению толщины сетчатки. Удаление эпиретинальной мембраны вместе с ВПМ вызывает снижение плотности сосудов ПСС и толщины ее слоев в зоне удаления ВПМ. Плотность сосудов ГСС остается неизменной во всех зонах, кроме фовеальной, где она снижается в отдаленном послеоперационном периоде (от 6 мес до 3 лет). Хирургия идиопатического ЭРФ с сохранением ВПМ является более целесообразной методикой в аспекте сохранения нормальных анатомических показателей микрососудистого русла и толщины сетчатки.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose: to evaluate the effect of removal and preservation of the internal limiting membrane (ILM) on the density of the microvascular bed (in the superficial and deep vascular plexuses of the retina) and retinal thickness in the macular region in older patients operated on for idiopathic epiretinal fibrosis (ERF).</p></sec><sec><title>Material and methods</title><p>Material and methods. The retrospective study included 103 patients (103 eyes) aged from 56 to 78 years (mean 67.1 ± 7.8 years) who underwent surgical treatment of idiopathic ERF. The patients were divided into 2 groups: the main group — where the ERF was removed while preserving the ILM (67 eyes) and the control group — where the ERF was removed along with the ILM (36 eyes). The vascular density of the superficial vascular plexus (SVP), deep vascular plexus (DVP) and retinal thickness were assessed using optical coherence tomography with angiography function. The period of observation of patients ranged from 6 months to 3 years.</p></sec><sec><title>Results</title><p>Results. When the ILM was preserved in all analyzed areas of the retina, the indicators of the density of the SVP and DVP were comparable with the indicators of the group of healthy individuals of the same age. The retinal thickness in all analyzed areas was not statistically different from the retinal thickness of healthy people. When the ILM was removed, the density of SVP was reduced in all analyzed areas of the retina compared with similar indicators in healthy patients. The density of DVP in the foveal area was reduced compared to this indicator in the control group and remained unchanged in other analyzed areas. Retinal thickness in all analyzed areas was reduced relative to retinal thickness in healthy people of the older age group.</p></sec><sec><title>Conclusion</title><p>Conclusion. Preservation of the ILM after removal of idiopathic ERF does not lead to a decrease in the density of the vascular bed and a decrease in retinal thickness. Removal of the ERM together with the ILM causes a decrease in the density of SVP and the retinal thickness around ILM removal. The density of DVP remains unchanged in all zones, except for the foveal area, where it decreases in the long-term postoperative period (from 6 months to 3 years). Surgery for idiopathic ERF with preservation of the ILM is a more appropriate technique in terms of preserving normal anatomical parameters of the microvascular bed and retinal thickness.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>эпиретинальная мембрана</kwd><kwd>эпиретинальный фиброз</kwd><kwd>внутренняя пограничная мембрана</kwd><kwd>пилинг внутренней пограничной мембраны</kwd><kwd>ОКТ-ангиография</kwd><kwd>плотность сосудов сетчатки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>epiretinal membrane</kwd><kwd>epiretinal fibrosis</kwd><kwd>internal limiting membrane</kwd><kwd>internal limiting membrane peeling</kwd><kwd>optical coherence tomography angiography</kwd><kwd>retinal vessel density</kwd><kwd>microvascular network</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">авторы не имеют финансовой заинтересованности в представленных материалах или методах</funding-statement><funding-statement xml:lang="en">no author has a financial or property interest in any material or method mentioned</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Fung AT, Galvin J, Tran T. 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