helmholtzeyeinstituteРоссийский офтальмологический журналRussian Ophthalmological Journal2072-00762587-5760Real time Publishers10.21516/2072-0076-2019-12-1-50-55helmholtzeyeinstitute-222Research ArticleКЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯCLINICAL STUDIESВлияние факоэмульсификации на состояние эндотелия роговицы у пациентов с псевдоэксфолиативным синдромомThe impact of phacoemulsification on corneal endothelial cells in patients with pseudoexfoliation syndromeПотемкинВ. В.PotemkinV. V.

канд. мед. наук, доцент кафедры офтальмологии, врач-офтальмолог

197022, Санкт-Петербург, ул. Льва Толстого, д. 6–8

194354, Санкт-Петербург, Учебный пер., д. 5

Cand. Med. Sci., ophthalmologist, assistant professor, chair of ophthalmology

6–8, Bldg 16, Lev Tolstoy St., St. Petersburg, 197089, Russia

5, Uchebny pereulok, St. Petersburg, 194354, Russia

ВаргановаТ. С.VarganovaT. S.

канд. мед. наук, врач-офтальмолог

194354, Санкт-Петербург, Учебный пер., д. 5

Cand. Med. Sci., ophthalmologist

5, Uchebny pereulok, St. Petersburg, 194354, Russia

АгееваЕ. В.AgeevaE. V.

 врач-офтальмолог

194354, Санкт-Петербург, Учебный пер., д. 5

ophthalmologist

5, Uchebny pereulok, St. Petersburg, 194354, Russia

ageeva_elena@inbox.ruГБОУ ВПО ПСПбГМУ им. акад. И.П. Павлова СПб ГБУЗ «Городская многопрофильная больница № 2»РоссияSt. Petersburg Pavlov State Medical University City Ophthalmologic Center of City hospital No. 2Russian FederationСПб ГБУЗ «Городская многопрофильная больница № 2»РоссияCity Ophthalmologic Center of City hospital No. 2Russian Federation2019150320191215055Copyright © Потемкин В.В., Варганова Т.С., Агеева Е.В., 20192019Потемкин В.В., Варганова Т.С., Агеева Е.В.Potemkin V.V., Varganova T.S., Ageeva E.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://roj.igb.ru/jour/article/view/222

Воздействие псевдоэксфолиативного синдрома (ПЭС) на клетки эндотелия является предметом изучения уже давно. Влияние же факоэмульсификации (ФЭ) на состояние эндотелия у пациентов с ПЭС изучено в меньшей степени. Цель — оценить влияние ФЭ на плотность эндотелиальных клеток роговицы и на коэффициент вариации у пациентов с ПЭС. Материал и методы. Обследовано 64 пациента (30 пациентов с ПЭС и 34 пациента без ПЭС). Всем пациентам была выполнена ФЭ. Плотность эндотелиальных клеток роговицы и коэффициент вариации оценивались до и после ФЭ. Результаты. У пациентов с ПЭС плотность клеток после ФЭ была достоверно ниже, коэффициент вариации достоверно выше (р < 0,05). Заключение. Наличие ПЭС оказывает отрицательное влияние на эндотелий роговицы и приводит к выраженной потере клеток после ФЭ.

The effect of pseudoexfoliation syndrome (PEХ) on endothelial cells has been studied long enough. Yet the effect of phacoemulsification (PHACO) on endothelium in patients with PEХ is less explored. Purpose. To assess the impact of PHACO on corneal endothelial cell density (ECD) and on the coefficient of variation (CV) in patients with PEX. Material and methods. 30 patients (30 eyes) with PEX syndrome and 34 patients (34 eyes) with no such syndrome were examined before and after phacoemulsification. Results. In patients with PEX, the ECD after PHACO was significantly lower and CV was significantly higher (р < 0.05). Conclusion. PEX has a negative impact on endothelial cells, which leads to a pronounced cells loss after PHACO.

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The authors declare that there are no conflicts of interest present.