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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">helmholtzeyeinstitute</journal-id><journal-title-group><journal-title xml:lang="ru">Российский офтальмологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Ophthalmological Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0076</issn><issn pub-type="epub">2587-5760</issn><publisher><publisher-name>Real time Publishers</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21516/2072-0076-2026-19-3-93-100</article-id><article-id custom-type="elpub" pub-id-type="custom">helmholtzeyeinstitute-2227</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>FOR OPHTHALMOLOGY PRACTITIONERS</subject></subj-group></article-categories><title-group><article-title>Рак слезной железы, симулирующий кисту орбиты. Описание клинического случая и анализ литературы</article-title><trans-title-group xml:lang="en"><trans-title>Lacrimal gland cancer simulating an orbital cyst. A case report and review of the literature</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Амирян</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Amiryan</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ануш Гамлетовна Амирян — д-р мед. наук, доцент, главный научный сотрудник отдела офтальмоонкологии и радиологии, доцент кафедры непрерывного медицинского образования.</p><p>Ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Anush G. Amiryan — Dr. of Med. Sci., principal researcher, ocular oncology and radiology department, associate professor of chair of continuing medical education.</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><email xlink:type="simple">amiryan@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гусакова</surname><given-names>М. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Gusakova</surname><given-names>M. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мария Юрьевна Гусакова — аспирант отдела офтальмоонкологии и радиологии.</p><p>Ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Maria Yu. Gusakova — PhD Student, ophthalmologist, ocular oncology and radiology department.</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жаров</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zharov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Андрей Александрович Жаров — врач-патологоанатом, научный сотрудник отдела патологической анатомии и гистологии.</p><p>Ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Andrey A. Zharov — ophthalmic pathologist, researcher, ocular pathology department.</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ глазных болезней им. Гельмгольца» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Helmholtz National Medical Research Center of Eye Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2026</year></pub-date><volume>19</volume><issue>3</issue><fpage>93</fpage><lpage>100</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Амирян А.Г., Гусакова М.Ю., Жаров А.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Амирян А.Г., Гусакова М.Ю., Жаров А.А.</copyright-holder><copyright-holder xml:lang="en">Amiryan A.G., Gusakova M.Y., Zharov A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://roj.igb.ru/jour/article/view/2227">https://roj.igb.ru/jour/article/view/2227</self-uri><abstract><p>Новообразования слезной железы (СЖ), несмотря на различную степень биологической агрессивности и прогноз, характеризуются достаточно схожим симптомокомплексом, а возможности дифференциальной диагностики с помощью инструментальных методов исследования крайне ограничены и малоспецифичны. Золотым стандартом диагностики новообразований СЖ является гистологическое исследование биоптата ткани опухоли. Несмотря на имеющиеся данные литературы, консенсус касательно тактики лечения таких пациентов до сих пор не достигнут. В свою очередь дооперационная неинвазивная дифференциальная диагностика злокачественных и доброкачественных новообразований СЖ остается весьма актуальной для формирования тактики ведения пациента, определения необходимости, сроков и объема хирургического вмешательства, оказывающего самое непосредственное влияние на витальный прогноз. Представлен клинический случай редкого варианта первичной протоковой аденокарциномы СЖ, долгое время симулирующей доброкачественное кистозное новообразование, с результатами клиникоинструментального и морфологического исследования.</p></abstract><trans-abstract xml:lang="en"><p>Lacrimal gland (LG) neoplasms vary in biological aggressiveness and prognosis, but often present with similar clinical features. Instrumental methods offer limited and nonspecific opportunities for differential diagnosis. Histological examination of tumor biopsy material remains the diagnostic gold standard. Despite published data, no consensus has been reached on the optimal treatment strategy for these patients. Preoperative noninvasive differentiation between malignant and benign LG neoplasms is therefore essential for choosing patient management, including the need, timing, and extent of surgery, which directly affects vital prognosis. We describe a rare case of primary ductal adenocarcinoma of the LG that for a long time mimicked a benign cystic lesion, and present the clinical, instrumental, and morphological findings.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>слезная железа</kwd><kwd>эпителиальные опухоли</kwd><kwd>новообразования слезной железы</kwd><kwd>рак слезной железы</kwd><kwd>аденокарцинома слезной железы</kwd><kwd>опухоли орбиты</kwd><kwd>экзофтальм</kwd></kwd-group><kwd-group xml:lang="en"><kwd>lacrimal gland</kwd><kwd>epithelial tumors</kwd><kwd>neoplasms of the lacrimal gland</kwd><kwd>cancer of the lacrimal gland</kwd><kwd>adenocarcinoma of the lacrimal gland</kwd><kwd>orbital tumors</kwd><kwd>exophthalmos</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">никто из авторов не имеет финансовой заинтересованности в представленных материалах или методах</funding-statement><funding-statement xml:lang="en">no author has a financial or property interest in any material or method mentioned</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Саакян С.В., Амирян А.Г., Вальский В.В., Миронова И.С., Майбогин А.М. 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