helmholtzeyeinstituteРоссийский офтальмологический журналRussian Ophthalmological Journal2072-00762587-5760Real time Publishers10.21516/2072-0076-2016-9-3-12-17helmholtzeyeinstitute-37Research ArticleКЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯCLINICAL STUDIESПЛАНИРОВАНИЕ НАВИГАЦИОННОЙ МАКУЛЯРНОЙ ЛАЗЕРНОЙ КОАГУЛЯЦИИ НА ОСНОВАНИИ КОНФОКАЛЬНОЙ СКАНИРУЮЩЕЙ ЛАЗЕРНОЙ ОФТАЛЬМОСКОПИИConfocal scanning laser ophthalmoscopy planning for navigated macular laser photocoagulationБойкоЭ. В.BoikoE. V.noemail@neicon.ruМальцевД. С.MaltsevD. S.noemail@neicon.ruСанкт-Петербургский филиал ФГУ МНТК «Микрохирургия глаза»РоссияSt. Petersburg Branch of the S. Fyodorov Eye Microsurgery Federal State Institution, RussiaRussian FederationФГБВОУ ВПО «Военно-медицинская академия им. С.М. Кирова», Санкт-ПетербургРоссияDepartment of Ophthalmology, Military Medical Academy, St Petersburg, RussiaRussian Federation201603102018931217Copyright © Бойко Э.В., Мальцев Д.С., 20182018Бойко Э.В., Мальцев Д.С.Boiko E.V., Maltsev D.S.This work is licensed under a Creative Commons Attribution 4.0 License.https://roj.igb.ru/jour/article/view/37

, p=0.007), в связи с большей площадью сканирования РР-СЛО. Заключение. Снимки РР-СЛО могут с успехом использоваться для планирования навигационной МЛК. Зоны лечения, основанные на РР-СЛО, имеют большую площадь, чем основанные на ОКТ// Российский офтальмологический журнал, 2016; 3: 12-17.

Purpose: To compare treatment areas and navigated macular laser photocoagulation (MLP) plans suggested by retro-mode scanning laser ophthalmoscopy (RM-SLO) image versus optical coherence tomography (OCT) retinal thickness map. Methods. 45 eyes of patients aged 63,1±10,2 years with diabetic or retinal vein occlusion-related ME were subjected to navigated MLP on the basis of OCT maps and RM-SLO images imported to NAVILAS navigated laser system. The plans for coagulant quantity based on OCT and RM-SLO images and the areas of retinal edema revealed by each method were compared. Results. The average number of laser spots using RM-SLO and OCT template was 171,2 ± 75,1 vs 125,9 ± 59,2 respectively, p = 0,002. The average area of edema on RM-SLO image was larger than that on OCT maps (14,9 ± 4,1 мм2 vs10,2 ± 2,9 mm2, p = 0,007) because of a larger scanning area. Conclusion. The RM SLO image can be used to guide MLP. The treatment areas suggested by RM-SLO-guided MLP plans for ME were shown to be larger than those suggested by OCT-guided plans // Russian Ophthalmological Journal, 2016; 3: 12-7. doi: 10.21516/2072-0076-2016-9-3-12-17

макулярный отекмакулярная лазерная коагулциясканирующая лазерная офтальмоскопияоптическая когерентная томографияmacular edemamacular laser photocoagulationscanning laser ophthalmoscopyoptical coherence tomographyReferencesБалашевич Л.И., Гацу М.В., Измайлов А.С. Отдаленные результаты лечения диффузного диабетического макулярного отека после панретинальной коагуляции в сочетании с лазеркоагуляцией в макуле. Офтальмохирургия. 2006; 3: 20-4.Балашевич Л.И., Гацу М.В., Измайлов А.С. Отдаленные результаты лечения диффузного диабетического макулярного отека после панретинальной коагуляции в сочетании с лазеркоагуляцией в макуле. Офтальмохирургия. 2006; 3: 20-4.Иванишко Ю.А. Диабетическая макулопатия: целесообразность и тактика превентивного лазерного вмешательства. Офтальмологический журнал. 1988; 4: 210-3.Иванишко Ю.А. Диабетическая макулопатия: целесообразность и тактика превентивного лазерного вмешательства. Офтальмологический журнал. 1988; 4: 210-3.The Branch Vein Occlusion Study Group. Argon laser photocoagulation for macular edema in branch vein occlusion. Am. J. Ophthalmol. 1984; 98: 271-82.The Branch Vein Occlusion Study Group. Argon laser photocoagulation for macular edema in branch vein occlusion. Am. J. Ophthalmol. 1984; 98: 271-82.Park Y.G., Kim E.Y., Roh Y.J. Laser-based strategies to treat diabetic macular edema: history and new promising therapies. J. Ophthalmol. 2014; Article ID 769213: 9.Park Y.G., Kim E.Y., Roh Y.J. Laser-based strategies to treat diabetic macular edema: history and new promising therapies. J. Ophthalmol. 2014; Article ID 769213: 9.Schneider E.W., Mruthyunjaya P., Hariprasad S.M. Combination therapy for macular edema secondary to retinal vein occlusion. Ophthalmic Surg Lasers Imaging Retina. 2013; 44(5): 434-8.Schneider E.W., Mruthyunjaya P., Hariprasad S.M. Combination therapy for macular edema secondary to retinal vein occlusion. Ophthalmic Surg Lasers Imaging Retina. 2013; 44(5): 434-8.Балашевич Л.И., Гацу М.В., Байбородов Я.В. Эффективность интравитреального введения кеналога при лечении рефрактерного диффузного диабетического макулярного отека, осложненного наличием твердых экссудатов. Офтальмохирургия. 2006; 2: 25-8.Балашевич Л.И., Гацу М.В., Байбородов Я.В. Эффективность интравитреального введения кеналога при лечении рефрактерного диффузного диабетического макулярного отека, осложненного наличием твердых экссудатов. Офтальмохирургия. 2006; 2: 25-8.Шадричев Ф.Е., Шкляров Е.Б., Григорьева Н.Н. Применение кортикостероидов в лечении диабетического маулярного отека. Офтальмологические ведомости. 2011; 4 (2): 76-88.Шадричев Ф.Е., Шкляров Е.Б., Григорьева Н.Н. Применение кортикостероидов в лечении диабетического маулярного отека. Офтальмологические ведомости. 2011; 4 (2): 76-88.Leitritz M.A., Gelisken F., Ziemssen F., et al. Grid laser photocoagulation for macular oedema due to branch retinal vein occlusion in the age of bevacizumab? Results of a prospective study with crossover design. Br. J. Ophthalmol. 2013; 97(2): 215-9.Leitritz M.A., Gelisken F., Ziemssen F., et al. Grid laser photocoagulation for macular oedema due to branch retinal vein occlusion in the age of bevacizumab? Results of a prospective study with crossover design. Br. J. Ophthalmol. 2013; 97(2): 215-9.Schatz H, Madeira D, McDonald HR, et al. Progressive enlargement of laser scars following grid laser photocoagulation for diffuse diabetic macular edema. Arch. Ophthalmol. 1991; 109: 1549-51.Schatz H, Madeira D, McDonald HR, et al. Progressive enlargement of laser scars following grid laser photocoagulation for diffuse diabetic macular edema. Arch. Ophthalmol. 1991; 109: 1549-51.Maeshima K., Utsugi-Sutoh N., Otani T., et al. Progressive enlargement of scattered photocoagulation scars in diabetic retinopathy. Retina. 2004; 24: 507-11.Maeshima K., Utsugi-Sutoh N., Otani T., et al. Progressive enlargement of scattered photocoagulation scars in diabetic retinopathy. Retina. 2004; 24: 507-11.Kozak I., Oster S.F., Cortes M.A., et al. Clinical evaluation and treatment accuracy in diabetic macular edema using navigated laser photocoagulator NAVILAS. Ophthalmology. 2011; 118(6): 1119-24.Kozak I., Oster S.F., Cortes M.A., et al. Clinical evaluation and treatment accuracy in diabetic macular edema using navigated laser photocoagulator NAVILAS. Ophthalmology. 2011; 118(6): 1119-24.Early Treatment Diabetic Retinopathy Study Research Group. Treatment techniques and clinical guidelines for photocoagulation of diabetic macular edema. Early Treatment Diabetic Retinopathy Study Report Number 2. Ophthalmology. 1987; 94 (7): 761-74.Early Treatment Diabetic Retinopathy Study Research Group. Treatment techniques and clinical guidelines for photocoagulation of diabetic macular edema. Early Treatment Diabetic Retinopathy Study Report Number 2. Ophthalmology. 1987; 94 (7): 761-74.Lobo C.L., Bernardes R.C., de Abreu J.R., Cunha-Vaz J.G. One-year follow-up of blood-retinal barrier and retinal thickness alterations in patients with type 2 diabetes mellitus and mild nonproliferative retinopathy. Arch Ophthalmol. 2001; 119(10): 1469-74.Lobo C.L., Bernardes R.C., de Abreu J.R., Cunha-Vaz J.G. One-year follow-up of blood-retinal barrier and retinal thickness alterations in patients with type 2 diabetes mellitus and mild nonproliferative retinopathy. Arch Ophthalmol. 2001; 119(10): 1469-74.Kozak I., El-Emam S.Y., Cheng L., et al. Fluorescein angiography versus optical coherence tomography-guided planning for macular laser photocoagulation in diabetic macular edema. Retina. 2014; 34(8): 1600-5.Kozak I., El-Emam S.Y., Cheng L., et al. Fluorescein angiography versus optical coherence tomography-guided planning for macular laser photocoagulation in diabetic macular edema. Retina. 2014; 34(8): 1600-5.Shin J.Y., Byeon S.H., Kwon O.W. Optical coherence tomography-guided selective focal laser photocoagulation: a novel laser protocol for diabetic macular edema. Graefes Arch Clin Exp Ophthalmol. 2015; 253 (4): 527-35.Shin J.Y., Byeon S.H., Kwon O.W. Optical coherence tomography-guided selective focal laser photocoagulation: a novel laser protocol for diabetic macular edema. Graefes Arch Clin Exp Ophthalmol. 2015; 253 (4): 527-35.Gallego-Pinazo R, Suelves-Cogollos AM, Dolz-Marco R et al. Macular laser photocoagulation guided by spectral-domain optical coherence tomography versus fluorescein angiography for diabetic macular edema. Clin Ophthalmol. 2011; 5: 613-7.Gallego-Pinazo R, Suelves-Cogollos AM, Dolz-Marco R et al. Macular laser photocoagulation guided by spectral-domain optical coherence tomography versus fluorescein angiography for diabetic macular edema. Clin Ophthalmol. 2011; 5: 613-7.Vujosevic S., Trento B., Bottega E., et al. Scanning laser ophthalmoscopy in the retro-mode in diabetic macular oedema. Acta Ophthalmol. 2012; 90(5): 374-80.Vujosevic S., Trento B., Bottega E., et al. Scanning laser ophthalmoscopy in the retro-mode in diabetic macular oedema. Acta Ophthalmol. 2012; 90(5): 374-80.Yamamoto M., Mizukami S., Tsujikawa A., Miyoshi N., Yoshimura N. Visualization of cystoid macular oedema using a scanning laser ophthalmoscope in the retro-mode. Clin Experiment Ophthalmol. 2010; 38 (1): 27-36.Yamamoto M., Mizukami S., Tsujikawa A., Miyoshi N., Yoshimura N. Visualization of cystoid macular oedema using a scanning laser ophthalmoscope in the retro-mode. Clin Experiment Ophthalmol. 2010; 38 (1): 27-36.Sull A.C., Vuong L.N., Price L.L. et al. Comparison of spectral/Fourier domain optical coherence tomography instruments for assessment of normal macular thickness. Retina. 2010; 30(2): 235-45.Sull A.C., Vuong L.N., Price L.L. et al. Comparison of spectral/Fourier domain optical coherence tomography instruments for assessment of normal macular thickness. Retina. 2010; 30(2): 235-45.Schneider M., Seres A., Borgulya G., Nemeth J. Boundary detection errors on optical coherence tomography images in patients with diabetic retinopathy. Ophthalmic Surg Lasers Imaging. 2010; 41(1): 54-9.Schneider M., Seres A., Borgulya G., Nemeth J. Boundary detection errors on optical coherence tomography images in patients with diabetic retinopathy. Ophthalmic Surg Lasers Imaging. 2010; 41(1): 54-9.

The authors declare that there are no conflicts of interest present.