helmholtzeyeinstituteРоссийский офтальмологический журналRussian Ophthalmological Journal2072-00762587-5760Real time Publishers10.21516/2072-0076-2020-13-2-41-44helmholtzeyeinstitute-426Research ArticleКЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯCLINICAL STUDIESОценка состояния электрогенеза сетчатки при ультрафиолетовом спектрофлуориметрическом исследовании глазаAssessment of retina electrogenesis in ultraviolet spectrofluorimetry of the eyeНероевВ. В.NeroevV. V.

Владимир Владимирович Нероев – академик РАН, проф., д-р мед. наук, директор

ул. Садовая-Черногрязская, д. 14/19, Москва, 105062

Vladimir V. Neroev – Academician of the Russian Academy of Sciences, Professor, Dr. of Med. Sci., director

14/19, Sadovaya Chernogryazskaya St., Moscow, 105062

ГарькавенкоВ. В.Gar’kavenkoV. V.

Виктор Валерьевич Гарькавенко – канд. мед. наук, врач-офтальмолог

ул. Никитина, д. 1в, Красноярск, 660011

Victor V. Gar’kavenko – Cand. of Med. Sci., MD, ophthalmologist

1 b, Nikitina st., Krasnoyarsk, 660011

victor-unique@yandex.ruШапироЛ. А.ShapiroL. A.

Людмила Афанасьевна Шапиро – доцент кафедры медицинской и биологической физики

ул. Партизана Железняка, д. 1, Красноярск, 660022

Ludmila A. Shapiro – Associate Professor, department of medical and biological physics

1, partizana Zhelezniaka st., Krasnoyarsk, 660022

СалминВ. В.SalminV. V.

Владимир Валерьевич Салмин – д-р физ.-мат. наук, доцент, заведующий кафедрой медицинской и биологической физики

ул. Партизана Железняка, д. 1, Красноярск, 660022

Vladimir V. Salmin – Dr. of Phys. Math. Sci., associate professor, head of department of medical and biological physics

1, partizana Zhelezniaka st., Krasnoyarsk, 660022

ФГБУ «НМИЦ глазных болезней им. Гельмгольца» Минздрава РоссииРоссияHelmholtz National Medical Research Center of Eye DiseasesRussian FederationКГБУЗ «Красноярская краевая офтальмологическая клиническая больница им. профессора П.Г. Макарова»РоссияKrasnoyarsk Makarov Regional Ophthalmological Clinical HospitalRussian FederationФГБОУ ВО «Красноярский государственный медицинский университет им. профессора В.Ф. Войно-Ясенецкого»РоссияKrasnoyarsk State Medical University named after Prof. V.F. Voino-YasenetskyRussian Federation2020260520201324144Copyright © Нероев В.В., Гарькавенко В.В., Шапиро Л.А., Салмин В.В., 20202020Нероев В.В., Гарькавенко В.В., Шапиро Л.А., Салмин В.В.Neroev V.V., Gar’kavenko V.V., Shapiro L.A., Salmin V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://roj.igb.ru/jour/article/view/426

Purpose was to study how ultraviolet (UV) light (365 nm) applied in low doses (1200 J·m-2), corresponding to the regimens of spectrofluorimetric analysis of the limbus and lens area, to the anterior eye chamber, affects bioelectric activity of the retina. Material and methods. A group of 25 volunteers (12 men and 13 women aged 21.0 ± 1.3 years) with no signs of ophthalmological or somatic pathology underwent spectrofluorimetric assessment of the limbus and lens area, followed by an evaluation of retina electrogenesis state. Results. We revealed no changes in the electric activity of the retina during the whole period of observation. The amplitude of A-wave varied from 75.2 mcV to 86.2 mcV both before and after the spectrofluorimetric examination. There were no significant changes in b-wave characteristics at any periods of investigation; b/a index did not demonstrate any difference from the baseline level. Conclusion. UV radiation (365 nm) of the anterior eye chamber in doses not exceeding those permitted by the SANPIN 5804-91 standard has no effect on the retinal function, should be considered safe, and can be used in future studies.

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The authors declare that there are no conflicts of interest present.