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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">helmholtzeyeinstitute</journal-id><journal-title-group><journal-title xml:lang="ru">Российский офтальмологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Ophthalmological Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0076</issn><issn pub-type="epub">2587-5760</issn><publisher><publisher-name>Real time Publishers</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21516/2072-0076-2021-14-2-50-54</article-id><article-id custom-type="elpub" pub-id-type="custom">helmholtzeyeinstitute-658</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Ковариационный анализ результатов запланированной  и фактически полученной гипокоррекции после  эксимерлазерной хирургии у пациентов среднего  возраста с миопической рефракцией</article-title><trans-title-group xml:lang="en"><trans-title>An ANCOVA analysis of the results of planned and actually  obtained hypocorrection after excimer laser surgery in  middle-aged patients with myopia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ходжабекян</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khodzhabekyan</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нарине Володяевна Ходжабекян— канд. мед. наук, ведущий научный сотрудник отдела патологии рефракции, бинокулярного зрения и офтальмоэргономики</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Narine V. Khodzhabekyan— Cand. of Med. Sci., leading researcher of the department of refraction pathology, binocular vision and ophthalmoergonomics</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарутта</surname><given-names>Е. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarutta</surname><given-names>E. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елена Петровна Тарутта— д-р мед. наук, профессор, начальник отдела патологии рефракции, бинокулярного зрения и офтальмо-эргономики</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Elena P. Tarutta — Dr. of Med. Sci., professor, head of the department of refraction pathology, binocular vision and ophthalmoergonomics</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ханджян</surname><given-names>А. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Khandzhyan</surname><given-names>A. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ануш Тиграновна Ханджян — канд. мед. наук, старший научный сотрудник отдела патологии сетчатки и зрительного нерва</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Anush T. Khandzhyan— Cand. of Med. Sci., senior researcher, department of retinal and optic nerve pathology</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сенгаева</surname><given-names>М. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Sengaeva</surname><given-names>M. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мария Дмитриевна Сенгаева — аспирант отдела патологии сетчатки и зрительного нерва</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Maria D. Sengaeva — PhD student of the department of retinal and optic nerve pathology</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><email xlink:type="simple">mariasengaeva@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анастасия Владимировна Иванова— канд. мед. наук, научный сотрудник отдела патологии рефракции, бинокулярного зрения и офтальмоэргономики</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Anastasia V. Ivanova— Cand. of Med. Sci., researcher of the department of refractive pathology, binocular vision and ophthalmoergonomics</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Летникова</surname><given-names>К. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Letnikova</surname><given-names>K. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ксения Борисовна Летникова— канд. мед. наук, научный сотрудник отдела патологии сетчатки и зрительного нерва</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Ksenia B. Letnikova — Cand. of Med. Sci., researcher of the department of retinal and optic nerve pathology</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Склярова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Sklyarova</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анна Сергеевна Склярова— канд. мед. наук, врач-офтальмолог отдела патологии сетчатки и зрительного нерва</p><p>ул. Садовая-Черногрязская, д. 14/19, Москва, 105062</p></bio><bio xml:lang="en"><p>Anna S. Sklyarova — Cand. of Med. Sci., ophthalmologist, department of retinal and optic nerve patholog</p><p>14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062</p><p> </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ глазных болезней им. Гельмгольца» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Helmholtz National Medical Research Center of Eye Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>19</day><month>06</month><year>2021</year></pub-date><volume>14</volume><issue>2</issue><fpage>50</fpage><lpage>54</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ходжабекян Н.В., Тарутта Е.П., Ханджян А.Т., Сенгаева М.Д., Иванова А.В., Летникова К.Б., Склярова А.С., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Ходжабекян Н.В., Тарутта Е.П., Ханджян А.Т., Сенгаева М.Д., Иванова А.В., Летникова К.Б., Склярова А.С.</copyright-holder><copyright-holder xml:lang="en">Khodzhabekyan N.V., Tarutta E.P., Khandzhyan A.T., Sengaeva M.D., Ivanova A.V., Letnikova K.B., Sklyarova A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://roj.igb.ru/jour/article/view/658">https://roj.igb.ru/jour/article/view/658</self-uri><abstract><p>Цель работы — провести к овариационный анализ результатов запланированной и фактически полученной рефракции после эксимерлазерной коррекции миопии у пациентов среднего возраста. Материал и методы. 85 пациентам (170 глаз) в возрасте 35–50 лет проведена эксимерлазерная коррекция миопии методом фемтоЛАСИК. Пациенты были разделены на группы в зависимости от степени миопии: 1-я группа включала 13 пациентов (26 глаз) с миопией от -1,25 до -3,0 дптр, 2-я группа — 42 пациента (84 глаза) с миопией от -3,25 до -6,0 дптр и 3-я группа — 30 пациентов (60 глаз) с миопией -6,25 дптр и выше. Результаты. Обнаружено, что у пациентов с миопией слабой степени вне зависимости от возраста полученный послеопе-рационный рефракционный эффект был ближе к запланированному, чем у пациентов с миопией средней и высокой степени. Различие (дельта) между запланированным и полученным результатом составило -0,35 ± 0,08 дптр (41 %) в 1-й группе, -0,58 ± 0,04 дптр (51,3 %) во 2-й и -0,64 ± 0,05 дптр (46 %) в 3-й, отличие между этими показателями в группе слабой и высокой миопии статистически достоверно (р &lt; 0,01). Заключение. Пациентам с миопией слабой степени в возрасте старше 35 лет можно планировать симметричную гипокоррекцию в бинокулярном формате без учета объективных данных об исходной гидратации роговицы, которая оказывает влияние на объем абляции. Для более точного совпадения запланированного и фактически полученного гипоэффекта, соответственно — определения адекватной дозировки операции, при миопии средней и высокой степени важно внедрение в клиническую практику технологии бесконтактного измерения гидратации роговицы.</p></abstract><trans-abstract xml:lang="en"><p>Purpose: a covariance analysis of the planned and actually obtained refraction after excimer laser myopia correction surgery in middle-aged patients. Material and methods. 85 patients (170 eyes) aged 35 to 50 underwent excimer laser myopia correction surgery by FemtoLASIK. The patients were divided into 3 groups according to the degree of myopia: group 1 included 13 patients (26 eyes) with myopia from -1.25 to -3.0 D, group 2 had 42 patients (84 myopic eyes) from -3.25 to -6.0 D and group 3 had 30 patients (60 eyes) with myopia of -6.25 D or higher. Results. The patients with low myopia, independently of the age, revealed a postoperative refraction effect closer to that planned than the patients with moderate and high myopia. The difference (delta) between the planned and the obtained results was -0.35 ± 0.08 D (41%) in group 1, -0.58 ± 0.04 D (51.3%) in group 2 and -0.64 ± 0.05 D (46%) in group 3. The divergence between the respective indicators for figures for low and high myopic groups is statistically significant. Conclusion.Patients with low myopia over 35 years old can be recommended a symmetric hypocorrection in binocular format irrespective of the objective data regarding the initial corneal hydration, which affects the ablation volume. To achieve a better agreement between the planned and the actual hypoeffect (and, accordingly, a more precise dosage of the surgery) in patients with moderate and high myopia, it is important to introduce into clinical practice the technology of contactless measurement of corneal hydration.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>миопия</kwd><kwd>гипокоррекция</kwd><kwd>фемтоЛасик</kwd><kwd>пресбиопия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>myopia</kwd><kwd>hypocorrection</kwd><kwd>FemtoLasik</kwd><kwd>presbyopia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Artola A., Patel S., Schimchak P., et al. Evidence for delayed presbyopia after photorefractive keratectomy for myopia. Ophthalmology. 2006; 113 (5): 735–41. doi: 10.1016/j.ophtha.2006.01.054</mixed-citation><mixed-citation xml:lang="en">Artola A., Patel S., Schimchak P., et al. 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