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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">helmholtzeyeinstitute</journal-id><journal-title-group><journal-title xml:lang="ru">Российский офтальмологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Ophthalmological Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0076</issn><issn pub-type="epub">2587-5760</issn><publisher><publisher-name>Real time Publishers</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21516/2072-0076-2022-15-2-supplement-38-43</article-id><article-id custom-type="elpub" pub-id-type="custom">helmholtzeyeinstitute-958</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Комплексная оценка офтальмогериатрических изменений у пациентов с влажной формой возрастной макулярной дегенерации</article-title><trans-title-group xml:lang="en"><trans-title>An integrated assessment of ophthalmogeriatric changes in patients with the wet form of agerelated macular degeneration</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Брежнев</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Brezhnev</surname><given-names>A. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Андрей Юрьевич Брежнев — канд. мед. наук, доцент кафедры офтальмологии</p><p>ул. К. Маркса, д. 3, Курск, 305041</p></bio><bio xml:lang="en"><p>Andrey Yu. Brezhnev — Cand. of Med. Sci, associate prof., chair ofophthalmology</p><p>3, Karl Marx St., Kursk, 305041</p></bio><email xlink:type="simple">drbrezhnev@hotmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андросова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Androsova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елена Александровна Андросова — аспирант кафедры офтальмологии</p><p>ул. К. Маркса, д. 3, Курск, 305041</p></bio><bio xml:lang="en"><p>Elena A. Androsova — PhD student, chair of ophthalmology</p><p>3, Karl Marx St., Kursk, 305041</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баранов</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Baranov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Валерий Иванович Баранов — д-р мед. наук, профессор, заведующий кафедрой офтальмологии</p><p>ул. К. Маркса, д. 3, Курск, 305041</p></bio><bio xml:lang="en"><p>Valery I. Baranov — Dr. of Med. Sci., professor, head of chair ofophthalmology</p><p>3, Karl Marx St., Kursk, 305041</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Курский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kursk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>16</day><month>06</month><year>2022</year></pub-date><volume>15</volume><issue>2 (Прил)</issue><issue-title>приложение</issue-title><fpage>38</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Брежнев А.Ю., Андросова Е.А., Баранов В.И., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Брежнев А.Ю., Андросова Е.А., Баранов В.И.</copyright-holder><copyright-holder xml:lang="en">Brezhnev A.Y., Androsova E.A., Baranov V.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://roj.igb.ru/jour/article/view/958">https://roj.igb.ru/jour/article/view/958</self-uri><abstract><p>Цель работы — комплексная оценка офтальмогериатрических изменений у пациентов с влажной формой возрастной макулярной дегенерации (ВМД) на этапе выявления заболевания.</p><sec><title>Материал и методы</title><p>Материал и методы. Обследовано 200 пациентов (43,5% мужчины, 56,5% женщины) пожилого и старческого возраста (60+ лет) с впервые выявленной влажной формой ВМД. Помимо стандартного офтальмологического обследования, проводилось анкетирование для выявления факторов риска, рассчитывался индекс массы тела (ИМТ) и индекс коморбидности (ИК) Чарлсона.</p></sec><sec><title>Результаты</title><p>Результаты. ИМТ составил 29,46 ± 4,1 кг/м2 , ИК — 3,3 [2; 4] балла при среднем количестве нозологий на одного больного с ВМД 4,0 [2; 6] (показатель варьировал от 1 до 7 заболеваний). Полипрагмазия имела место в 8% случаев. Дегенеративные изменения конъюнктивы встречались у 11% обследованных, старческая дуга — у 34,5%, дистрофия радужной оболочки — в 68%, псевдоэксфолиативный синдром — в 17,5%, сенильная катаракта — в 89,5%, дегенеративные изменения стекловидного тела — в 84,5%, первичная открытоугольная глаукома — в 2% случаев. Гендерных различий по этим показателям не выявлено. Среди системных заболеваний наиболее часто встречалась кардио- и цереброваскулярная патология (артериальная гипертензия — 74,5%, ишемическая болезнь сердца — 40,5%, цереброваскулярная патология — 20,5%). Сахарный диабет II типа обнаружен у 6,5% пациентов (при этом у женщин этот показатель более чем в 2 раза выше, чем у мужчин).</p></sec><sec><title>Заключение</title><p>Заключение. Влажная форма ВМД характеризуется широким спектром коморбидных состояний, способных оказать влияние на основное заболевание, в том числе за счет полипрагмазии.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose. Integrated assessment of ophthalmogeriatric changes in patients with the wet form of age-related macular degeneration (AMD) at the time of primary diagnosis.</p></sec><sec><title>Material and methods</title><p>Material and methods. 200 senior and senile patients aged 60 or more (of which 43.5% were male) with the newly diagnosed wet AMD underwent a standard ophthalmological examination, took a survey aimed at identifying specific risk factors, and tested for Body Mass Index (BMI) and Charlson Comorbidity Index (CCI).</p></sec><sec><title>Results</title><p>Results. The BMI was 29.46 ± 4.1 kg/m2 and the CCI was 3.3 [2; 4]. The average number of disorders per patient with AMD was 4.0 [2; 6] (ranging from 1 to 7). Polypragmasia took place in 8% of cases. Degenerative changes in the conjunctiva were found in 11%, arcus senilis — in 34.55%, dystrophic changes of the iris — in 68%, pseudoexfoliation syndrome — in 17.5%, senile cataract — in 89.5%, degenerative changes of the vitreous — in 84.5%, primary open-angle glaucoma — in 2% of cases. No gender differences were revealed in these indicators. Among systemic diseases, the most frequent were cardiac and cerebrovascular pathologies (arterial hypertension — 74.5%, ischaemic heart disease — 40.5%, cerebrovascular pathology — 20.5%). Type 2 diabetes mellitus was found in 6.5% of AMD patients.</p></sec><sec><title>Conclusion</title><p>Conclusion. The wet form of AMD is characterized by a wide range of comorbid disorders that can affect the development and progression of the main disease. Polypragmasia plays its own role in this progression.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>возрастная макулярная дегенерация</kwd><kwd>офтальмогериатрия</kwd><kwd>коморбидность</kwd><kwd>возраст-ассоциированные заболевания глаз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>age-related macular degeneration</kwd><kwd>geriatric ophthalmology</kwd><kwd>comorbidity</kwd><kwd>age-related eye disorders</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kirkwood T.B. A systematic look at an old problem. Nature. 2008; 451 (7179): 644–7. doi: 10.1038/451644a</mixed-citation><mixed-citation xml:lang="en">Kirkwood T.B. A systematic look at an old problem. 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