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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">helmholtzeyeinstitute</journal-id><journal-title-group><journal-title xml:lang="ru">Российский офтальмологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Ophthalmological Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0076</issn><issn pub-type="epub">2587-5760</issn><publisher><publisher-name>Real time Publishers</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21516/2072-0076-2022-15-2-42-48</article-id><article-id custom-type="elpub" pub-id-type="custom">helmholtzeyeinstitute-990</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Масочный синдром сухого глаза: степень выраженности и возможности коррекции с использованием слезозаместительной терапии</article-title><trans-title-group xml:lang="en"><trans-title>Dry eye masky syndrome: degree of expression and possibilities of correction</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3943-1188</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макогон</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Makogon</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Светлана Ивановна Макогон, канд. мед. наук, доцент, заведующая отделением</p><p>ФГБОУ ВО «Алтайский государственный медицинский университет»</p><p>кафедра оториноларингологии с курсом офтальмологии</p><p>656038</p><p>проспект Ленина, д. 40</p><p>взрослое офтальмологическое поликлиническое отделение</p><p>656002</p><p>ул. Советская, д. 8</p><p>Алтайский край</p><p>Бар­наул</p></bio><bio xml:lang="en"><p>Svetlana I. Makogon, Cand. of Med. Sci., associate professor, head of department</p><p>adult ophthalmological outpatient department</p><p>656038</p><p>chair of otorhinolaryngology with the course of ophthalmology</p><p>40, Lenin Avenue</p><p>656002</p><p>8, Sovetskaya St.</p><p>Altai Territory</p><p>Barnaul</p></bio><email xlink:type="simple">vvk_msi@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5586-9796</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горбачева</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorbacheva</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Наталья Владимировна Горбачева, ассистент кафедры, врач-офтальмолог</p><p>ФГБОУ ВО «Алтайский государственный медицинский университет»</p><p>кафедра оториноларингологии с курсом офтальмологии</p><p>656038</p><p>проспект Ленина, д. 40</p><p>взрослое офтальмологическое поликлиническое отделение</p><p>656002</p><p>ул. Советская, д. 8</p><p>Алтайский край</p><p>Бар­наул</p></bio><bio xml:lang="en"><p>Natalya V. Gorbacheva, assistant, ophthalmologist</p><p>chair of otorhinolaryngology with the course of ophthalmology</p><p>656038</p><p>40, Lenin Avenue</p><p>656002</p><p>8, Sovetskaya St.</p><p>Altai Territory</p><p>Barnaul</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1138-8904</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>D. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дарья Ивановна Иванова, ассистент кафедры, врач-офтальмолог</p><p>ФГБОУ ВО «Алтайский государственный медицинский университет»</p><p>кафедра оториноларингологии с курсом офтальмологии</p><p>656038</p><p>проспект Ленина, д. 40</p><p>взрослое офтальмологическое поликлиническое отделение</p><p>656002</p><p>ул. Советская, д. 8</p><p>Алтайский край</p><p>Бар­наул</p></bio><bio xml:lang="en"><p>Darya I. Ivanova, assistant, ophthalmologist</p><p>chair of otorhinolaryngology with the course of ophthalmology</p><p>656038</p><p>40, Lenin Avenue</p><p>656002</p><p>8, Sovetskaya St.</p><p>Altai Territory</p><p>Barnaul</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7615-2057</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хлопкова</surname><given-names>Ю. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Khlopkova</surname><given-names>Yu. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юлия Сергеевна Хлопкова, ассистент кафедры</p><p>ФГБОУ ВО «Алтайский государственный медицинский университет»</p><p>кафедра оториноларингологии с курсом офтальмологии</p><p>656038</p><p>проспект Ленина, д. 40</p><p>Алтайский край</p><p>Бар­наул</p></bio><bio xml:lang="en"><p>Yulia S. Khlopkova, assistant</p><p>chair of otorhinolaryngology with the course of ophthalmology</p><p>656038</p><p>40, Lenin Avenue</p><p>Altai Territory</p><p>Barnaul</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Минздрав России; КГБУЗ «Алтайская краевая офтальмологическая больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Altai State Medical University; Altai Regional Ophthalmological Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Минздрав России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Altai State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>12</day><month>07</month><year>2022</year></pub-date><volume>15</volume><issue>2</issue><fpage>42</fpage><lpage>48</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Макогон С.И., Горбачева Н.В., Иванова А.И., Хлопкова Ю.С., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Макогон С.И., Горбачева Н.В., Иванова А.И., Хлопкова Ю.С.</copyright-holder><copyright-holder xml:lang="en">Makogon S.I., Gorbacheva N.V., Ivanova D.I., Khlopkova Y.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://roj.igb.ru/jour/article/view/990">https://roj.igb.ru/jour/article/view/990</self-uri><abstract><p>   Для предотвращения распространения COVID-19, обеспечения безопасности для себя и окружающих в нашу повседневную жизнь прочно вошли средства индивидуальной защиты (СИЗ) — различные виды масок.</p><p>   Цель работы — провести клинико-со­циологическое исследование степени выраженности синдрома сухого глаза (ССГ) у медицинского персонала и студентов-медиков на фоне использования СИЗ и оценить возможности его коррекции.</p><sec><title>   Материал и методы</title><p>   Материал и методы. Проанализированы результаты обследования 138 человек медицинского персонала и 149 студентов. Проведено анкетирование для выявления факторов риска развития ССГ. Суммарную продукцию слезы определяли с помощью теста Ширмера Iв начале и через 8 ч рабочего дня у меди­цинского персонала, а также до и после 6-часовых занятий у студентов. Для оценки возможности коррекции ССГ студентам предложены инстилляции слезозаместителя Гилан 0,18 % 3 раза в день. На этом этапе исследования для оценки выраженностисимптомов ССГ использовали тест Ширмера I и два опросника: OSDI и DEQ.</p></sec><sec><title>   Результаты</title><p>   Результаты. Большинство участников исследо­вания отметили постоянное ношение масок (86,4 % врачей и 84,8 % среднего медицинского персонала). На начало исследования у 45,1 % врачей, 51,9 % среднего медицинского персонала и у 45,6% студентов показатели суммарной слезопродукции были ниже референтных значений. По окончании рабочего времени у врачей (90,9 %), среднего медицинского персонала (88,6 %) и студентов (69,2 %) наблюдалось снижение показателя суммарной слезопродукции разной степени выраженности. Использование слезоза­менителя позволило повысить показатели суммарной слезопродукции: через 10 дней после лечения в 45,7 % случаях наблюдалось увеличение (но значения были в пределах 10—14 мм), в 31,4 % случаев достигли 15 мм и более и превысили исходные значения (р &lt; 0,05); уменьшить ССГ: число студентов, имеющих по опроснику DEQ ССГ на начало исследования (62,9 %), уменьшилось в 3,2 раза.</p></sec><sec><title>   Заключение</title><p>   Заключение. Ношение масок можно рассматривать как фактор риска развития ССГ. Назначение слезозаместительной терапии позволило улучшить функциональные показатели слезы и качество жизни. Необходима разработка и реализация меро­приятий, направленных на выявление и профилактику развития ССГ не только у медицинского персонала, но и у населения в целом.</p></sec></abstract><trans-abstract xml:lang="en"><p>   To prevent the spread of COVID-19, to ensure the safety of ourselves and others, personal protective equipment — various types of masks — has firmly entered our daily lives.</p><p>   Purpose to conduct a clinical and sociological study of the severity of the dry eye syndrome in medical personnel and medical students against the background of the use of personal protective equipment and to assess the possibilities of its correction using tear replacement therapy.</p><sec><title>   Materials and methods</title><p>   Materials and methods. 138 medical staff and 149 students were analyzed. A survey was conducted to identify risk factors for the development of the dry eye syndrome. The total tear production was determined using the Schirmer I test at the beginning and after 8 hours of the working day in medical personnel and students before and after a 6-hour lesson. To study the possibility of correcting the dry eye syndrome, students were offered instillations of the tear substitute Gylan 0.18 % 3 times a day. At this stage of the study, 2 questionnaires were used to assess the severity of DES symptoms: OSDI and DEQ, Schirmer I test.</p></sec><sec><title>   Results</title><p>   Results. Most of the study participants noted the constant wearing of masks (86.4 % of doctors and 84.8 % of nurses). At the beginning of the study, 45.1 % of doctors and 51.9 % of nursing staff, 45.6 % of students had indicators of total tear production below the reference values. At the end of working hours, doctors (90.9 %), nurses (88.6 %) and students (69.2 %) showed a decrease in the total tear production of varying severity. The use of a tear substitute made it possible to increase the indicators of total tear production: 10 days after treatment, an increase was observed in 45.7 % of cases (but the values were in the range of 10—14 mm), in 31.4 % of cases they reached 15 mm or more and exceeded the initial values (p &lt; 0.05); reduce the symptoms of dry eye: the number of students with DEQ questionnaire syndrome dry eye at the beginning of the study (62.9 %) decreased by 3.2 times.</p></sec><sec><title>   Conclusions</title><p>   Conclusions: the conducted study allows us to speak about the currently available riskfactorfor the development of the dry eye syndrome: personal respiratory protective equipment has a negative impact on the indicators of total tear production. Appointment of tear replacement therapy allowed to improve the functional indicators of tears and quality of life. It is necessary to develop and implement measures aimed at identifying and preventing the development of the dry eye syndrome not only among medical personnel, but also among the population as a whole.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>масочный синдром сухого глаза</kwd><kwd>средства индивидуальной защиты дыхания</kwd><kwd>проба Ширмера I</kwd><kwd>медицинский персонал</kwd><kwd>студенты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>mask-associated dry eye syndrome</kwd><kwd>personal respiratory protection equipment</kwd><kwd>Schirmer's test 1</kwd><kwd>medical personnel</kwd><kwd>students</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Авторы не имеют финансовой заинтересованности в представленных материалах или методах.</funding-statement><funding-statement xml:lang="en">The authors have no financial or property interest in any material or method mentioned</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lan J., Song Z., Miao X., et al. 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