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Inactive Graves’ orbitopathy: to treat or not to treat?

https://doi.org/10.21516/2072-0076-2023-16-1-59-64

Abstract

Purpose: to evaluate the expediency and efficacy of conservative therapy of patients with inactive stages of Graves’ orbitopathy complicated by optical neuropathy. Materials and methods. 62 patients with an inactive stage of Graves’ orbitopathy complicated by optical neuropathy were divided into two groups: group 1 (21 patients, 33.9%) received only symptomatic and local therapy, while group 2 (41 patients, 66.1%) additionally received periorbital injections of glucocorticoid drugs. The patients were examined clinically and instrumentally before and after treatment as well as after a long period of more than 12 months. Results. A positive clinical effect of treatment confirmed by positive dynamics of functional indices of computer perimetry (MS, MD) was achieved in 44 cases (71%), of which 33 patients (75.0% ) belonged to group 2. Positive changes in group 1 were achieved in 52.4% of cases and in group 2 in 80.5% of patients. Long-term results showed stable positive changes in 92.1% of cases. Conclusion. The need for complex therapy, involving local injections of glucocorticoid drugs, of patients in an inactive stage of Grave’s orbitopathy who develop symptoms of optical neuropathy was substantiated.

About the Authors

O. G. Panteleeva
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation

Olga G. Panteleeva — Dr. of Med. Sci., leading researcher, ocular oncology department, associate professor, chair of continuing medical education

14/19, Sadovaya Chernogryazskaya St., Moscow, 105062



F. H. Batyrbekova
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation

Fatima H. Batyrbekova — ophthalmologist, out-patient department

14/19, Sadovaya Chernogryazskaya St., Moscow, 105062



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For citations:


Panteleeva O.G., Batyrbekova F.H. Inactive Graves’ orbitopathy: to treat or not to treat? Russian Ophthalmological Journal. 2023;16(1):59-64. (In Russ.) https://doi.org/10.21516/2072-0076-2023-16-1-59-64

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ISSN 2072-0076 (Print)
ISSN 2587-5760 (Online)