Internal limiting membrane peeling in vitreoretinal surgery for rhegmatogenous retinal detachment: clinical results, surgical options, and future prospects
https://doi.org/10.21516/2072-0076-2024-17-1-149-155
Abstract
Rhegmatogenous retinal detachment (RRD) is one of the leading causes of primary vision disability, while the majority of RRD patients with RRD are people of active working age. Over the past 50 years, retinal detachment surgery has been progressing rapidly, the rate of success increasing up to 90% or higher. However, the reduction of reoperation risks of reoperations, improvement of functional outcomes and increase of postoperative visual acuity remain topical issues. The main reason for repeated surgical interventions is the proliferative vitreoretinopathy progression, which can lead to epiretinal fibrosis, macular oedema, or retinal detachment recurrence. The review is focused on current literature studies that report the results of internal limiting membrane peeling in cases of RRD surgeries and other optional techniques aimed at reducing the risk of the above mentioned postoperative complications.
About the Authors
R. R. Fayzrakhmanov
N.I. Pirogov National Medical and Surgical Center, Institute of Continuous Medical Education; National N.I. Pirogov Medical and Surgical Center
Russian Federation
Russian Federation
Rinat R. Fayzrakhmanov — Dr. of Med. Sci., professor, head of chair of eye diseases, N.I. Pirogov National Medical and Surgical Center, Institute of Continuous Medical Education; head of center of ophthalmology, National N.I. Pirogov Medical and Surgical Center
65, Nizhnyaya Pervomayskaya St.,Moscow, 105203
70, Nizhnyaya Pervomaiskaya St., Moscow, 105203
M. M. Shishkin
N.I. Pirogov National Medical and Surgical Center, Institute of Continuous Medical Education; National N.I. Pirogov Medical and Surgical Center
Russian Federation
Russian Federation
Michail M. Shishkin — Dr. of Med. Sci., professor, professor of chair of eye diseases, N.I. Pirogov National Medical and Surgical Center, Institute of Continuous Medical Education; principal ophthalmologist of Center of Ophthalmology, National N.I. Pirogov Medical and Surgical Center
65, Nizhnyaya Pervomayskaya St.,Moscow, 105203
70, Nizhnyaya Pervomaiskaya St., Moscow, 105203
V. S. Klev
National N.I. Pirogov Medical and Surgical Center
Russian Federation
Russian Federation
Valeriya S. Klev — ophthalmologist of the center of ophthalmology
70, Nizhnyaya Pervomaiskaya St., Moscow, 105203
O. L. Sekhina
N.I. Pirogov National Medical and Surgical Center, Institute of Continuous Medical Education
Russian Federation
Russian Federation
Olga L. Sekhina — PhD of chair of eye diseases of the Institute for advanced training of doctors
65, Nizhnyaya Pervomayskaya St.,Moscow, 105203
E. E. Vaganova
N.I. Pirogov National Medical and Surgical Center, Institute of Continuous Medical Education
Russian Federation
Russian Federation
Elena E. Vaganova — postgraduate student of chair of eye diseases of the Institute for advanced training of doctors
65, Nizhnyaya Pervomayskaya St.,Moscow, 105203
D. M. Mamadaliev
National N.I. Pirogov Medical and Surgical Center
Russian Federation
Russian Federation
Dilshot M. Mamadaliev — Cand. of Med. Sci., surgion
70, Nizhnyaya Pervomaiskaya St., Moscow, 105203
References
1. Neroev V.V. Ophthalmology: clinical recommendations. Moscow: GEOTAR-Media; 2020 (In Russ.)
2. Osmanov R.E. Modern methods of surgical treatment of rhegmatogenous retinal detachment. Vestnik Tambovskogo universiteta. Seriya: Estestvennye i tekhnicheskie nauki. 2015; 20 (3): 658–62 (In Russ.)
3. Fabrikantov O.L., Shmykov A.V. The role of vitreoretinal interface in the pathogenesis of retinal detachment (literary review). Vestnik Orenburgskogo gosudarstvennogo universiteta. 2013; 153 (4): 280–3 (In Russ.)
4. Machemer R, van Horn D, Aaberg TM. Pigment epithelial proliferation in human retinal detachment with massive periretinal proliferation. Am J Ophthalmol. 1978 Feb; 85 (2): 181–91. doi: 10.1016/s0002-9394(14)75946-x
5. Campo RV, Sipperley JO, Sneed SR, et al. Pars plana vitrectomy without scleral buckle for pseudophakic retinal detachments. 1999 Sep; 106 (9): 1811–5; discussion 1816. doi: 10.1016/S0161-6420(99)90353-6
6. Kolesnik S.V., Kolesnik A.I., Miridonova A.V., Avakyan F.A., Zhuravlev A.S. ILM removal in vitreomacular interface disorders: for or against? Fyodorov journal of ophthalmic surgery. 2021; 3: 83–8 (In Russ.) https://doi.org/10.25276/0235-4160-2021-3-83-88
7. Bikbov M.M., Fayzrakhmanov R.R., Kalanov M.R., Zainullin R.M. Efficiency of vitrectomy in combination with internal limiting membrane peeling associated with the gas-air tamponade of the vitreous cavity at the advanced stage of proliferative diabetic retinopathy. Fyodorov journal of ophthalmic surgery. 2017; 3. 22–6 (In Russ.) doi: 10.25276/0235-4160-2017-3-22-26
8. Kadonosono K, Itoh N, Uchio E, Nakamura S, Ohno S. Staining of internal limiting membrane in macular hole surgery. Arch Ophthalmol. 2000 Aug; 118 (8): 1116–8. doi: 10.1001/archopht.118.8.1116
9. Hisatomi T, Enaida H, Sakamoto T, et al. Cellular migration associated with macular hole: A new method for comprehensive bird’s-eye analysis of the internal limiting membrane. Arch Ophthalmol. 2006; 124 (7): 1005–11. doi: 10.1001/archopht.124.7.1005
10. Kelly NE, Wendel RT. Vitreous surgery for idiopathic macular holes. Results of a pilot study. Arch Ophthalmol. 1991 May; 109 (5): 654–9. doi: 10.1001/archopht.1991.01080050068031
11. Haugstad M, Moosmayer S, Bragad ttir R. Primary rhegmatogenous retinal detachment — surgical methods and anatomical outcome. Acta Ophthalmol. 2017; 95 (3): 247–51. doi: 10.1111/aos.13295
12. Rao RC, Blinder KJ, Smith BT, Shah GK. Internal limiting membrane peeling for primary rhegmatogenous retinal detachment repair. Ophthalmology. 2013; 120 (5): 1102–3e1-2. doi: 10.1016/j.ophtha.2012.12.010
13. Nam KY, Kim JY. Effect of internal limiting membrane peeling on the development of epiretinal membrane after pars plana vitrectomy for primary rhegmatogenous retinal detachment. Retina. 2015 May; 35 (5): 880–5. doi: 10.1097/IAE.0000000000000421
14. Aras C, Arici C, Akar S, et al. Peeling of internal limiting membrane during vitrectomy for complicated retinal detachment prevents epimacular membrane formation. Graefes Arch Clin Exp Ophthalmol. 2009 May; 247 (5): 619–23. doi: 10.1007/s00417-008-1025-y
15. Odrobina DC, Michalewska Z, Michalewski J, Nawrocki J. High-speed, high-resolution spectral optical coherence tomography in patients after vitrectomy with internal limiting membrane peeling for proliferative vitreoretinopathy retinal detachment. Retina. 2010 Jun; 30 (6): 881–6. doi: 10.1097/IAE.0b013e3181c96952
16. Fallico M, Russo A, Longo A, et al. Internal limiting membrane peeling versus no peeling during primary vitrectomy for rhegmatogenous retinal detachment: A systematic review and meta-analysis. PLoS ONE. 2018; 13 (7): e0201010. doi: 10.1371/journal.pone.0201010
17. Zaharov V.D., Shkvorchenko D.O., Kakunina S.A., Norman K.S., Fozilova F.F. The effectiveness of peeling the inner boundary membrane against the background of silicone tamponade in regmatogenic retinal detachment. Tavrichesky medico-biological bulletin. 2018; 21 (4): 23–7 (In Russ.)
18. Akiyama K, Fujinami K, Watanabe K, et al. Internal limiting membrane peeling to prevent post-vitrectomy epiretinal membrane development in retinal detachment. Am J Ophthalmol. 2016; 171: 1–10.
19. Obata S, Kakinoki M, Sawada O, et al. Effect of internal limiting membrane peeling on postoperative visual acuity in macula-off rhegmatogenous retinal detachment. PLoS ONE. 2021; 16 (8): e0255827. https://doi.org/10.1371/journal.pone.0255827
20. Starr MR, Obeid A, Gao X, et al. Prophylactic internal limiting membrane peeling during rhegmatogenous retinal detachment surgery. Acta Ophthalmol. 2021; 99: e619-e620. https://doi.org/10.1111/aos.14560
21. Bawankule PK, Narnaware SH, Raje DV, Chakraborty M. Internal limiting membrane peel: Does it change the success rate of primary vitrectomy without belt buckle in rhegmatogenous retinal detachments? Indian J Ophthalmol. 2019; 67 (9): 1448–54. doi: 10.4103/ijo.IJO_1685_18
22. Poulsen C, Green D, Grauslund J, Peto T. Long-term outcome of patients operated with pars plana vitrectomy for primary rhegmatogenous retinal detachment. Ophthalmic Res. 2020; 63 (1): 25–33. doi: 10.1159/000499130
23. Mitry D, Awan MA, Borooah S, et al. Surgical outcome and risk stratification for primary retinal detachment repair: results from the Scottish Retinal Detachment study. Br J Ophthalmol. 2012; 96 (5): 730–4. doi: 10.1136/bjophthalmol-2011-300581
24. Mitry D, Awan MA, Borooah S, et al. Long-term visual acuity and the duration of macular detachment: findings from a prospective population-based study. Br J Ophthalmol. 2013; 97 (2): 149–52. doi: 10.1136/bjophthalmol-2012-302330
25. Klaas JE, Rechl P, Feucht N, et al. Functional recovery after macula involving retinal detachment and its correlation with preoperative biomarkers in optical coherence tomography. Graefes Arch Clin Exp Ophthalmol. 2021 Sep; 259 (9): 2521–2531. doi: 10.1007/s00417-021-05113-3
26. Foveau P, Leroy B, Berrod JP, Conart JB. Internal limiting membrane peeling in macula-off retinal detachment complicated by grade b proliferative vitreoretinopathy. Am J Ophthalmol. 2018 Jul; 191: 1–6. doi: 10.1016/j.ajo.2018.03.037
27. Abdullah ME, Moharram HEM, Abdelhalim AS, et al. Evaluation of primary internal limiting membrane peeling in cases with rhegmatogenous retinal detachment. Int J Retin Vitr. 2020; (6): 8. https://doi.org/10.1186/s40942-020-00213-4
28. Garweg JG, Deiss M, Pfister IB, Gerhardt C. Impact of inner limiting membrane peeling on visual recovery after vitrectomy for primary rhegmatogenous retinal detachment involving the fovea. Retina. 2019 may; 39 (5): 853–859. doi: 10.1097/iae.0000000000002046. PMID: 29394235.
29. Akhundova L.A. Internal limiting peeling for rhegmatogenous retinal detachment. Oftalmologiya Elmi Praktik Jurnal. 2015; 1 (17): 49–54 (In Russ.)
30. Eissa M, Abdelhakim M, Macky TA, Khafagy MM, Mortada HA. Functional and structural outcomes of ILM peeling in uncomplicated macula-off RRD using microperimetry & en-face OCT. Graefes Arch Clin Exp Ophthalmol. 2018; 256 (2): 249–57.
31. Ripandelli G, Scarinci F, Piaggi P, et al. Macular pucker: To peel or not to peel the internal limiting membrane? A microperimetric response. Retina. 2015; 35 (3): 498–507. doi: 10.1097/IAE.0000000000000330
32. Arias L, Padr n-P rez N, Flores-Moreno I, et al. A swept-source optical coherence tomography study with a new postoperative classification system. Retina. 2020 Jul; 40 (7): 1286–1298. doi: 10.1097/IAE.0000000000002591
33. Haritoglou C, Gandorfer A, Gass C.A, et al. Indocyanine green-assisted peeling of the internal limiting membrane in macular hole surgery affects visual outcome: a clinicopathologic correlation. Am J Ophtalmol. 2002 Dec; 134 (6): 836–41. doi: 10.1016/s0002-9394(02)01816-0
34. Deltour JB, Grimbert P, Masse H, et al. Detrimental effects of active internal limiting membrane peeling during epiretinal membrane surgery — microperimetric analysis. Retina. 2017 Mar; 37 (3): 544–552. doi: 10.1097/IAE.0000000000001179
35. Aznabaev B.M., Dibaev T.I., Husniyarova A.R. Intraoperative OCT-assisted vitreoretinal surgery. Saratov journal of medical scientific research 2018; 14 (4): 849–55 (In Russ.)
36. Awh C, Bass E. A Microsurgical vacuum pick for membrane peeling without forceps during vitreoretinal surgery. Ophthalmic Surgery, Lasers and Imaging Retina. 2020; 51: 196–9. doi: 10.3928/23258160-20200228-09
37. Lyskin P.V. New data of mechanism in vitreoretinal adhesion and posterior vitreous detachment in humans. Russian ophthalmology of children. 2019; 2: 57–62 (In Russ.)]. doi: https://doi.org/10.25276/2307-6658-2019-2-57-62
38. Kimura H, Kuroda S, Nagata M. Premacular cortical vitreous in patients with a rhegmatogenous retinal detachment. Retina. 2004 Apr; 24 (2): 329–30. doi: 10.1097/00006982-200404000-00032
39. Cho EH, Ku HC, Il W, Lee EK. Residual vitreous cortex at the fovea during vitrectomy for primary rhegmatogenous retinal detachment repair. Retina. 2018 Aug; 38 (8): 1549–1555. doi: 10.1097/IAE.0000000000001734
40. Kato Y, Inoue M, Hirakata A. Effect of foveal vitreous cortex removal to prevent epiretinal membrane after vitrectomy for rhegmatogenous retinal detachment. Ophthalmol Retina. 2021 May; 5 (5): 420–428. doi: 10.1016/j.oret.2020.08.020
41. Lyskin P.V. The impact of clostridial collagenase on epiretinal structures of the human retina. Russian ophthalmology of children. 2019; 1: 34–8 (In Russ.)]. https://doi.org/10.25276/2307-6658-2019-1-34-38
42. Zgoba M.I., Lyskin P.V., Makarenko I.R. Bacterial collagenase in the treatment of vitreoretinal pathology (review). Saratov journal of medical scientific research. 2018; 14 (4): 953–6 (In Russ)
Review
For citations:
Fayzrakhmanov R.R., Shishkin M.M., Klev V.S., Sekhina O.L., Vaganova E.E., Mamadaliev D.M. Internal limiting membrane peeling in vitreoretinal surgery for rhegmatogenous retinal detachment: clinical results, surgical options, and future prospects. Russian Ophthalmological Journal. 2024;17(1):149-155. (In Russ.) https://doi.org/10.21516/2072-0076-2024-17-1-149-155
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