Genetic factors of myopia
https://doi.org/10.21516/2072-0076-2025-18-1-125-130
Abstract
The purpose of the work is to study the genetic features of myopia manifestation according to modern data of domestic and foreign literature. The analysis of recent publications on the issues of myopia genetics is presented. The review is performed using the keywords of this topic in the PubMed, Scopus, eLibrary.ru databases. Myopia is a complex condition with many genetic variants of development both according to the Mendelian type of inheritance and as a complex disease caused by the joint contribution of several polymorphic genes that interact or act independently. It is necessary to conduct further genetic studies in various regions of our country and abroad for the development of possible individual approaches to the treatment of myopia with the choice of the age of treatment initiation, as well as to the prevention of its occurrence and progression.
About the Authors
A. E. Aprelev
Orenburg State Medical University
Russian Federation
Russian Federation
Alexander E. Aprelev — Dr. of Med. Sci., associate professor, head of chair of ophthalmology.
6, Sovetskaya St., Orenburg, 460000
S. V. Cherkasov
Institute for Cellular and Intracellular Symbiosis of the Ural Branch of the Russian Academy of Sciences, Orenburg Federal Research Center of the UrB RAS
Russian Federation
Russian Federation
Sergey V. Cherkasov — Dr. of Med. Sci., professor, corresponding member of the Russian Academy of Sciences, principal researcher, head of laboratory of biomedical technologies.
11, Pionerskaya St., Orenburg, 460000
A. D. Chuprov
Orenburg branch of S. Fyodorov Eye Microsurgery Center
Russian Federation
Russian Federation
Alexander D. Chuprov — Dr. of Med. Sci., professor, director.
17, Salmyshskaya St., Orenburg, 460047
V. E. Aprelev
Orenburg State Medical University
Russian Federation
Russian Federation
Vadim E. Aprelev — Dr. of Med. Sci., assistant professor, chair of neurology and medical genetics.
6, Sovetskaya St., Orenburg, 460000
E. Y. Antokhin
Orenburg State Medical University
Russian Federation
Russian Federation
Evgeniy Yu. Antokhin — Cand. of Med. Sci., assistant professor, head of chair of clinical psychology and psychotherapy.
6, Sovetskaya St., Orenburg, 460000
A. A. Aprelev
Orenburg State Medical University
Russian Federation
Russian Federation
Alexandr A. Aprelev — clinical resident, chair of ophthalmology.
6, Sovetskaya St., Orenburg, 460000
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Review
For citations:
Aprelev A.E., Cherkasov S.V., Chuprov A.D., Aprelev V.E., Antokhin E.Y., Aprelev A.A. Genetic factors of myopia. Russian Ophthalmological Journal. 2025;18(1):125-130. (In Russ.) https://doi.org/10.21516/2072-0076-2025-18-1-125-130
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