Preview

Russian Ophthalmological Journal

Advanced search

Micropulse cyclophotocoagulation in the treatment of various types of glaucoma. Part 2: MPCPC at different stages of glaucoma, in combined ophthalmopathology and in congenital glaucoma

https://doi.org/10.21516/2072-0076-2025-18-1-138-144

Abstract

Micropulse cyclophotocoagulation (MPCPC) is a relatively new method of laser treatment of glaucoma, which has actively entered clinical practice due to its effectiveness, relative safety, technical simplicity of implementation and speed of training. The first part of the review presents the history, mechanisms of action and protocol for performing MPCPC [ROJ. 2024; 17 (4): 111–115]. The second part of the review is devoted to the place of MPCPC in the stepwise paradigm of glaucoma treatment, including in patients with high visual acuity. An analysis of existing publications on the possibility of using MPCPC in patients with combined pathology and in children is also presented.

About the Authors

O. V. Ermakova
S. Fedorov Eye Microsurgery Center, Novosibirsk Branch
Russian Federation

Olga V. Ermakova — Сand. of Med. Sci., head of 2nd ophthalmology department.

10, Kolkhidskaya St., Novosibirsk, 630096



E. A. Ragozina
S. Fedorov Eye Microsurgery Center, Novosibirsk Branch
Russian Federation

Ekaterina A. Ragozina — ophthalmologist.

10, Kolkhidskaya St., Novosibirsk, 630096



References

1. Egbert PR, Fiadoyor S, Budenz DL, Dadzie P, Byrd S. Diode laser transscleral cyclophotocoagulation as a primary surgical treatment for primary open-angle glaucoma. Arch Ophthalmol. 2001; 119 (3): 345–50. doi: 10.1001/archopht.119.3.345

2. Michelessi M, Bicket AK, Lindsley K. Cyclodestructive procedures for non-refractory glaucoma. Cochrane Database Syst Rev. 2018 Apr 25; 4 (4): CD009313. doi: 10.1002/14651858.CD009313.pub2

3. Bernardi E, Töteberg-Harms M. MicroPulse Transscleral Laser therapy demonstrates similar efficacy with a superior and more favorable safety profile compared to continuous-wave transscleral cyclophotocoagulation. J Ophthalmol. 2022 Feb 8; 2022: 8566044. doi: 10.1155/2022/8566044

4. Chen HS, Yeh PH, Yeh CT, et al. Micropulse transscleral cyclophotocoagulation in a Taiwanese population: 2-year clinical outcomes and prognostic factors. Graefes Arch Clin Exp Ophthalmol. 2022; 260 (4): 1265–73. doi: 10.1007/s00417-021-05468-7

5. Basto RC, Almeida J, Roque JN, et al. Clinical outcomes of micropulse transscleral cyclophotocoagulation: 2 years of experience in portuguese eyes. J Curr Glaucoma Pract. 2023; 17 (1): 30–6. doi: 10.5005/jp-journals-10078-1395

6. Khodzhaev N.S., Sidorova A.V., Starostina A.V., Eliseeva M.A. Micropulse transscleral cyclophotocoagulation for the treatment of glaucoma. Russian ophthalmological journal. 2020; 13 (2): 105–11 (In Russ.). doi:org/10.21516/2072-0076-2020-13-2-105-111

7. Rajendrababu S, Senthilkumar VA, Tara TD, et al. Short-term outcomes of micropulse transscleral cyclophotocoagulation as a primary versus additional therapy in eyes with uncontrolled glaucoma. Indian J Ophthalmol. 2023; 71 (1): 140–5. doi: 10.4103/ijo.IJO_1289_22

8. Sidorova A.V., Khodzhaev N.S., Eliseeva M.A., Starostina A.V. Drainage surgery of refractory glaucoma in combination with micro-pulse cyclophotocoagulation. Saratovskij nauchno-medicinskij zhurnal. 2020; 16 (1): 273–6 (In Russ.). https://ssmj.ru/2020/1/273

9. Sidorova A.V., Kozlova E.E., Eliseeva M.A., Budaeva T.A. Method of combined treatment of primary angle-closure glaucoma. Patent RF № 2741374; 2021 (In Russ.).

10. Sidorova A.V., Starostina A.V., Eliseeva M.A., Smirnova E.A. Method of combined treatment of severe forms of refractory glaucoma. Patent RF № 2741373; 2021 (In Russ.).

11. Khodzhaev N.S., Sidorova A.V., Eliseeva M.A. Micropulse transscleral cyclophotocoagulation in the combine treatment of neovascular glaucoma. Novosti glaukomy. 2020; 1 (53): 71–5 (In Russ.). doi: 10.25276/2227-8281-1-71-75

12. Varikuti VNV, Shah P, Rai O, et al. Outcomes of micropulse transscleral cyclophotocoagulation in eyes with good central vision. J Glaucoma. 2019; 28 (10): 901–5. doi: 10.1097/IJG.0000000000001339

13. Kurysheva N.I., Radzhabov M.M. Transscleral cyclophotocoagulation in the micropulse mode in the treatment of the initial stage of primary open angle glaucoma. Sovremennye tekhnologii v oftal’mologii. 2020; (4): 156 (In Russ.). doi: 10.25276/2312-4911-2020-4-136-137

14. Ioshin I.E., Tolchinskaya A.I., Maximov I.V. Comparative analysis of treatment of patients with refractory glaucoma of various stages by microimpulse transscleral cyclophotocoagulation. Ophthalmology in Russia. 2022; 19 (2): 318–24 (In Russ.). https://doi.org/10.18008/1816-5095-2022-2-318-324

15. Ioshin I.E., Tolchinskaya A.I., Rakova A.V., Maksimov I.V. Results of micropulse cyclophotocoagulation in patients with early stages of primary open-angle glaucoma. Naczional’ny’i zhurnal Glaukoma. 2022; 21 (4): 22–8 (In Russ.). doi: 10.53432/2078-4104-2022-21-4-22-28

16. Tekeli O, Köse HC. Comparative efficacy and safety of micropulse transscleral laser cyclophotocoagulation using different duration protocols in eyes with good visual acuity. Graefes Arch Clin Exp Ophthalmol. 2021; 259 (11): 3359–69. doi: 10.1007/s00417-021-05265-2

17. Kuciel-Polczak I, Helemejko M, Dobrowolski D, et al. Assessment of the effectiveness of glaucoma treatment using micropulse transscleral cyclophotocoagulation in patients with glaucoma who have previously undergone vitreoretinal surgery. Ophthalmol Ther. 2023; 12 (1): 179–93. doi: 10.1007/s40123-022-00598-5

18. Sokolovskaja T.V., Belousova E.V., Kislicyna N.M., Ibragimova R.R. Hypotensive effect of micropulse laser cyclophotocoagulation in hemophthalmos with high intraocular pressure. Sovremennye tekhnologii v oftal’mologii. 2021; 3 (38): 262–4 (In Russ.). doi: 10.25276/2312-4911-2021-3-262-264

19. Sidorova A.V., Eliseeva M.A., Smirnova E.A. The application possibilities of the method of combined surgical treatment of secondary glaucoma causing by silicone emulsification. Sovremennye tekhnologii v oftal’mologii. 2019; 1: 169–72 (In Russ.). doi: 10.25276/2312-4911-2019-1-169-172

20. Anders LM, Gatzioufas Z, Grieshaber MC. Challenges in the complex management of post-keratoplasty glaucoma. Ther Adv Ophthalmol. 2021 Jul 20; 13: 25158414211031397. doi: 10.1177/25158414211031397

21. Sidorova A.V., Starostina A.V., Pecherskaia M.A., Stefankova K.A. Advantages of micropulse technology as a method of choice for the treatment of secondary glaucoma in patients with corneal diseases. Ophthalmology in Russia. 2022; 19 (3): 515–23 (In Russ.). https://doi.org/10.18008/1816-5095-2022-3-515-523

22. Sidorova A.V., Geljastanov A.M., Eliseeva M. A. The application possibilities of the technology micropulse in treatment of secondary glaucoma in patients after keratoplasty (clinical case). Sovremennye tekhnologii v oftal’mologii. 2019; 5: 342–5 (In Russ.). doi: 10.25276/2312-4911-2019-5-342-345

23. Zemba M, Dumitrescu OM, Stamate AC, et al. Micropulse transscleral cyclophotocoagulation for glaucoma after penetrating keratoplasty. Diagnostics (Basel). 2022; 12 (5): 1143. doi: 10.3390/diagnostics12051143

24. Lee JH, Vu V, Lazcano-Gomez G, et al. Clinical outcomes of micropulse transscleral cyclophotocoagulation in patients with a history of keratoplasty. J Ophthalmol. 2020 Jul 9; 2020: 6147248. doi: 10.1155/2020/6147248

25. Ermakova O.V. A two-step surgical approach for the treatment of cataract and secondary glaucoma associated with severe scleromalacia. Sovremennye tekhnologii v oftal’mologii. 2020; (35): 127–8 (In Russ.). doi: 10.25276/2312-4911-2020-4-127-128

26. Shvailikova I.E., Belikova E.I., Korneeva A.V. The results of transscleral diode laser cyclophotocoagulation in micropulse mode treatment in patients with primary subcompensated open-angle glaucoma and toxic-allergic syndrome of the ocular surface. Ophthalmology in Russia. 2021; 18 (1): 77–82 (In Russ.). https://doi.org/10.18008/1816-5095-2021-1-77-82

27. Bruskov I.A., Ermakova O.V. A method of combined surgical treatment of glaucoma in combination with cataracts. Patent RF # 2769820 RF; 2022 (In Russ.).

28. Daas A, Sherman T, Danieliute L. Phacoemulsification combined with micropulse cyclodiode laser in glaucoma patients: efficacy and safety. Eye (Lond). 2022; 36 (11): 2188–91. doi: 10.1038/s41433-021-01826-1

29. Panova A.Yu., Katargina L.A., Denisova E.V., Sorokin A.A. Immediate results of micropulse cyclophotocoagulation in glaucoma in children. Russian pediatric ophthalmology. 2022; 17 (3): 21–9 (In Russ.). doi: https://doi.org/10.17816/rpoj107300

30. Konikova O.A., Diskalenko O.V. Micropulse cyclophotocoagulation in the treatment of refractory glaucoma in children. Sovremennye tekhnologii v oftal’mologii. 2020; 4 (35): 213–4 (In Russ.). doi: 10.25276/2312-4911-2020-4-213-214

31. Sokolovskay T.V., Tikhonova M.I. Micropulse transscleral diode laser cyclophotocoagulation in the treatment of congenital glaucoma. Oftal’mokhirurgiya. 2019; 3: 44–7 (In Russ.). doi: 10.25276/0235-4160-2019-3-44-47

32. Elhefney EM, Mokbel TH, Hagras SM, et al. Micropulsed diode laser cyclophotocoagulation in recurrent pediatric glaucoma. Eur J Ophthalmol. 2020; 30 (5): 1149–55. doi: 10.1177/1120672119858226

33. Abdelrahman AM, El Sayed YM. Micropulse versus continuous wave transscleral cyclophotocoagulation in refractory pediatric glaucoma. J Glaucoma. 2018; 27 (10): 900–5. doi: 10.1097/IJG.0000000000001053

34. Lee JH, Shi Y, Amoozgar B, et al. Outcome of micropulse laser transscleral cyclophotocoagulation on pediatric versus adult glaucoma patients. J Glaucoma. 2017; 26 (10): 936–9. doi: 10.1097/IJG.0000000000000757

35. Lim EJY, Aquino CM, Lun KWX, et al. Efficacy and safety of repeated micropulse transscleral diode cyclophotocoagulation in advanced glaucoma. J Glaucoma. 2021; 30 (7): 566–74. doi: 10.1097/IJG.0000000000001862

36. Hooshmand S, Voss J, Hirabayashi M, McDaniel L, An J. Outcomes of initial and repeat micro-pulse transscleral cyclophotocoagulation in adult glaucoma patients. Ther Adv Ophthalmol. 2022 Feb 14; 14: 25158414211064433. doi: 10.1177/25158414211064433

37. Ioshin I.E., Tolchinskay A.I., Maksimov I.V., Rakova A.V. Repeated micropulse cyclophotocoagulation in the treatment of refractory glaucoma. A clinical experience. Russian ophthalmological journal. 2022; 15 (3): 18–25 (In Russ.). doi:10.21516/2072-0076-2022-15-3-18-25


Review

For citations:


Ermakova O.V., Ragozina E.A. Micropulse cyclophotocoagulation in the treatment of various types of glaucoma. Part 2: MPCPC at different stages of glaucoma, in combined ophthalmopathology and in congenital glaucoma. Russian Ophthalmological Journal. 2025;18(1):138-144. (In Russ.) https://doi.org/10.21516/2072-0076-2025-18-1-138-144

Views: 117


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2072-0076 (Print)
ISSN 2587-5760 (Online)