Preview

Russian Ophthalmological Journal

Advanced search

Application of machine learning algorithms to improve the accuracy of laser vision correction outcomes

https://doi.org/10.21516/2072-0076-2025-18-3-supplement-23-26

Abstract

Laser vision correction (LVC) is a high-technology method of correcting refractive errors, the effectiveness of which largely depends on the precision of preoperative diagnostics, the individualization of surgical parameters, and the accurate prediction of postoperative outcomes. In recent years, machine learning (ML) algorithms have been increasingly integrated at various stages of the LVC process, contributing to the transformation of ophthalmic surgical practice toward a more personalized approach. This literature review aims to systematize current advancements in the application of ML in laser refractive surgery. In the preoperative phase, ML enables the accurate selection of suitable candidates, the identification of contraindications (including keratoconus), the choice of optimal surgical technique, and the calculation of ablation parameters. Employed algorithms, such as random forest, XGBoost, and deep neural networks, exhibit excellent sensitivity and specificity, frequently outperforming conventional clinical methods. In the postoperative period, ML is utilized to predict visual outcomes, assess the risk of refractive regression, and determine the likelihood of enhancement procedures. Despite its high predictive accuracy, the current use of artificial intelligence (AI) remains constrained by the retrospective nature of available data, the lack of large-scale clinical validation, and the ongoing need for integration into clinical workflows. This review underscores the importance of further research to establish standardized protocols, ensure interoperability, and achieve regulatory compliance for AI-based solutions in ophthalmology.

About the Authors

A. V. Osipov
N.I. Pirogov Russian National Research Medical University
Russian Federation

Arseny V. Osipov — PhD student, chair of ophthalmology, institute of continuous education and professional development

1, Ostrovityanova St., Moscow, 117997



L. V. Batalina
N.I. Pirogov Russian National Research Medical University
Russian Federation

Larisa V. Batalina — Cand. of Med. Sci., associate professor, chair of ophthalmology, institute of continuous education and professional development

1, Ostrovityanova St., Moscow, 117997



N. N. Dergacheva
N.I. Pirogov Russian National Research Medical University
Russian Federation

Nadezhda N. Dergacheva — Cand. of Med. Sci., associate professor, chair of ophthalmology, institute of continuous education and professional development

1, Ostrovityanova St., Moscow, 117997



I. B. Medvedev
N.I. Pirogov Russian National Research Medical University
Russian Federation

Igor B. Medvedev — Dr. of Med. Sci., professor, head of chair of ophthalmology, institute of continuous education and professional development

1, Ostrovityanova St., Moscow, 117997



References

1. Chang JY, Lin PY, Hsu CC, Liu CJ. Comparison of clinical outcomes of LASIK, Trans-PRK, and SMILE for correction of myopia. J Chin Med Assoc. 2022 Feb 1; 85 (2): 145–51. doi: 10.1097/JCMA.0000000000000674

2. Neroev V.V., Zaytseva O.V., Petrov S.Yu., Bragin A.A. Artificial intelligence in ophthalmology: the present and the future. Russian ophthalmological journal. 2024; 17 (2): 135–41 (In Russ.)]. https://doi.org/10.21516/2072-0076-2024-17-2-135-141

3. Choi JY, Kim DE, Kim SJ, et al. Application of multimodal large language models for safety indicator calculation and contraindication prediction in laser vision correction. NPJ Digital Medicine. 2025; 8 (1): 82. https://doi.org/10.1038/s41746-025-01487-4

4. Kundu G, Virani I, Shetty R, et al. Role of artificial intelligence in determining factors impacting patients’ refractive surgery decisions. Indian Journal of Ophthalmology. 2023; 71 (3): 810–7. https://doi.org/10.4103/ijo.ijo_2718_22

5. Yoo TK, Ryu IH, Lee G, et al. Adopting machine learning to automatically identify candidate patients for corneal refractive surgery. NPJ Digit Med. 2019 Jun 20; 2: 59. doi: 10.1038/s41746-019-0135-8

6. Yoo TK, Ryu IH, Choi H, et al. Explainable machine learning approach as a tool to understand factors used to select the refractive surgery technique on the expert level. Transl Vis Sci Technol. 2020 Feb 12; 9 (2): 8. doi: 10.1167/tvst.9.2.8

7. Xie Y, Zhao L, Yang X, et al. Screening candidates for refractive surgery with corneal tomographic-based deep learning. JAMA Ophthalmol. 2020 May 1; 138 (5): 519–26. doi: 10.1001/jamaophthalmol.2020.0507

8. Li J, Dai Y, Mu Z, et al. Choice of refractive surgery types for myopia assisted by machine learning based on doctors’ surgical selection data. BMC Med Inform Decis Mak. 2024 Feb 8; 24 (1): 41. doi: 10.1186/s12911-024-02451-0

9. Park S, Kim H, Kim L, et al. Artificial intelligence-based nomogram for smallincision lenticule extraction. Biomed Eng Online. 2021 Apr 23; 20 (1): 38. doi: 10.1186/s12938-021-00867-7

10. Luft N, Mohr N, Spiegel E, et al. Optimizing refractive outcomes of SMILE: Artificial Intelligence versus Conventional State-of-the-Art Nomograms. Curr Eye Res. 2024 Mar; 49 (3): 252–9. doi: 10.1080/02713683.2023.2282938

11. Wan Q, Yue S, Tang J, et al. Prediction of early visual outcome of smallincision lenticule extraction (SMILE) based on deep learning. Ophthalmol Ther. 2023 Apr; 12 (2): 1263–79. doi: 10.1007/s40123-023-00680-6

12. Balidis M, Papadopoulou I, Malandris D, et al. Using neural networks to predict the outcome of refractive surgery for myopia. 4open. 2019; 229. https://doi.org/10.1051/fopen/2019024


Review

For citations:


Osipov A.V., Batalina L.V., Dergacheva N.N., Medvedev I.B. Application of machine learning algorithms to improve the accuracy of laser vision correction outcomes. Russian Ophthalmological Journal. 2025;18(3):23-26. (In Russ.) https://doi.org/10.21516/2072-0076-2025-18-3-supplement-23-26

Views: 24


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2072-0076 (Print)
ISSN 2587-5760 (Online)