Evaluating the effectiveness of a sodium cromoglycate group drug in the treatment of allergic conjunctivitis
https://doi.org/10.21516/2072-0076-2020-13-2-36-40
Abstract
Purpose. To study the effectiveness and tolerability of sodium cromoglycate (Uzbekistan) in the treatment of allergic conjunctivitis. Material and methods. 60 patients (120 eyes) with allergic conjunctivitis aged 18 to 60 years (28 men and 32 women), were divided into two homogeneous groups with similar clinical manifestations. The main group (30 patients), in addition to basic treatment, received instillations of sodium cromoglycate, 2 drops 4 times a day for 4 weeks. The control group (30 patients) received a foreign medication of the same group, instilled in the same way. Results. The patients of both groups revealed a comparable therapeutic effect. By the end of the treatment course, substantial positive changes were observed and the symptoms of allergic inflammation disappeared. The treatment effectiveness was 95.9 and 97.6 % in the main and the control groups, respectively. Conclusion. The use of domestic medication of the sodium cromoglycate group reduces the patients’ subjective complaints and helps achieve a maximum therapeutic effect at a price affordable by the patient and the clinic. No side effects or cases of intolerance to the drug of sodium cromoglycate group used have been revealed.
About the Authors
S. Sh. Mirrakhimova
Samarkand Regional Ophthalmological Clinic
Uzbekistan
Uzbekistan
Saida Sh. Mirrakhimova – Dr. of Med. Sci., associate professor, chief medical officer
78А, 1st Shaar proezd, Samarkand, 140100
K. I. Narzikulova
Tashkent Medical Academy
Uzbekistan
Uzbekistan
Kumri I. Narzikulova – Dr. of Med. Sci., associate professor
2, Farobi St., Tashkent, 100109
J. O. Safarov
Bukhara State Medical Institute
Uzbekistan
Uzbekistan
Jahongir O. Safarov – assistant
1, prospekt Navoi, Bukhara, 200118
References
1. Maychuk Yu.F. Seasonal pollinosis conjunctivitis is the most common form of eye allergosis. Part I. Epidemiology, etiology, pathophysiology, clinic, diagnostics. Russian Ophthalmological Journal. 2010; 3 (1): 37–41 (in Russian).
2. Bakhritdinova F.A. Etiopathogenesis, clinical and epidemiological features and treatment of allergic conjunctivitis with pollinosis in Uzbekistan. Moscow: Misl; 2000 (in Russian).
3. Neroev V.V., Vakhova E.S. Allergic conjunctivitis. Ophthalmology: National Guide. In the book: Avetisov S.E., Egorov E.A., Moshetova L.K., et al., eds. 2nd ed. Moscow: GEOTAR-Media; 2018: 442–56 (in Russian).
4. Brzhesky V.V. Some information about the prevalence and current treatment options for spring keratoconjunctivitis. Russian Ophthalmological Journal. 2017; 10 (4): 74–81 (in Russian).
5. Maychuk D.Yu., Chilingaryan L.B. Tear replacement therapy for allergic eye conditions. Ophthalmology. 2012; 2 (9): 72–6 (in Russian).
6. Brzesky V.V. Allergic conjunctivitis: a guide for an outpatient ophthalmologist. Medical Review. 2018; 1 (2): 74–9 (in Russian).
7. Kryukov A.I., Ivoylov A.Yu., Pakina V.R., et al. Drug therapy for allergic rhinitis in children. Medical advice. 2014; 3: 55–60 (in Russian).
8. O'Brien T.P. Allergic conjunctivitis: an update on diagnosis and management. Curr. Opin. Allergy Clin. Immunol. 2013; 13 (5): 543–9. doi: 10.1097/ACI.0b013e328364ec3a
9. Belousova T.A., Goryachkina M.V., Pyatilova P.M. Antihistamines in clinical practice: optimization of choice from the standpoint of pharmacoeconomics. Medical Review. 2015; 4: 230 (in Russian).
10. Akdis C.A., Jutel M., Akdis M. Regulatory effects of histamine and histamine receptor expression in human allergic immune responses. Chem. Immunol. Allergy. 2008; 94: 67–82. doi: 10.1159/000154858
11. La Rosa M., Lionetti E., Reibaldi M., et al. Allergic conjunctivitis: a comprehensive review of the literature. Ital. J. Pediatr. 2013; 39: 18. doi: 10.1186/1824-7288-39-18
12. Egorov A.E., Zakharova M.A. Treatment of a patient with allergic conjunctivitis: recommendations for an outpatient ophthalmologist. Ophthalmology. 2017; 2: 111–4 (in Russian).
13. Nurpeisov T.T., Talgatbekova D.Zh., Tarabaeva A.S. The clinical effectiveness of levocetirizine in the treatment of allergic rhinitis with conjunctivitis. Bulletin of the Kazakh National Medical University. 2017; 4: 471–3 (in Russian).
14. Ackerman S., Smith L., Gomes P. J. Ocular itch associated with allergic conjunctivitis: latest evidence and clinical management. Ther. Adv. Chronic Dis. 2016; 7 (1): 52–67. doi: 10.1177/2040622315612745
15. Stewart W.C, Stewart J.A, Mychaskiw M.A. Cost effectiveness of latanoprost and timolol maleate for the treatment of glaucoma in Scandinavia and the United Kingdom using a decision analytic health economic. Eye. 2009; 23 (1): 132–40.
Review
For citations:
Mirrakhimova S.Sh., Narzikulova K.I., Safarov J.O. Evaluating the effectiveness of a sodium cromoglycate group drug in the treatment of allergic conjunctivitis. Russian Ophthalmological Journal. 2020;13(2):36-40. (In Russ.) https://doi.org/10.21516/2072-0076-2020-13-2-36-40
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