A personalized approach to preclinical diagnosis and initial therapy of primary glaucoma based on a comprehensive structural and functional examination. A clinical case
https://doi.org/10.21516/2072-0076-2021-14-4-110-117
Abstract
The principles of personalized approach to early diagnosis and monitoring of primary glaucoma are shown by a clinical example. We analyzed the potentials of contemporary electrophysiological tests for preclinically diagnosing glaucoma optic neuropathy and monitoring drug treatment. For the first time, we demonstrated the experience of using a new fixed combination of brinzolamide + brimonidine by a clinical case from our practice. The test results confirm the hypotensive effect of the medication (IOP reduction by 36.2 %) so that it can be recommended for the treatment of patients with glaucomatous optic neuropathy and that combined with vascular pathology.
About the Authors
A. N. Zhuravleva
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation
Russian Federation
Anastasiya N. Zhuravleva — Cand. of Med. Sci., researcher, glaucoma department
14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062
M. V. Zueva
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation
Russian Federation
Marina V. Zueva — Dr. of Biol. Sci., professor, head of the department of clinical physiology of vision named after S.V. Kravkov
14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062
S. Y. Petrov
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation
Russian Federation
Sergey Y. Petrov — Dr. of Med. Sci., head of the glaucoma department
14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062
M. O. Kirillova
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation
Russian Federation
Maria O. Kirillova — PhD student, glaucoma department
14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062
S. M. Kosakyan
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation
Russian Federation
Srbui M. Kosakyan — Cand. of Med. Sci., ophthalmologist, department of glaucoma
14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062
I. V. Tsapenko
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation
Russian Federation
Irina V. Tsapenko — Cand. of Biol. Sci., senior researcher, department of clinical physiology of vision named after S.V. Kravkov
14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062
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Review
For citations:
Zhuravleva A.N., Zueva M.V., Petrov S.Y., Kirillova M.O., Kosakyan S.M., Tsapenko I.V. A personalized approach to preclinical diagnosis and initial therapy of primary glaucoma based on a comprehensive structural and functional examination. A clinical case. Russian Ophthalmological Journal. 2021;14(4):110-117. (In Russ.) https://doi.org/10.21516/2072-0076-2021-14-4-110-117
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