Changes of corneal epithelial thickness before and after OK-correction according to SD-OCT
https://doi.org/10.21516/2072-0076-2017-10-3-49-54
Abstract
Purpose: to evaluate the thickness of corneal epithelium after orthokeratological (OK) correction with the help of SDOCT. Material and methods: 18 patients (36 eyes) averagely aged 12.11 ± 1.68 with myopia of -3.21 ± 0.94 D and axial length of 24.47 ± 0.7 mm were examined. All patients were checked for corneal epithelial thickness (ET) with the help of SD-OCT Avanti RTVueXR (Optovue Inc., Fremont, CA, USA), which created maps of 6 mm in diameter before OK correction with lenses ESA-DL (Dr. Lens Technology, Russia) and 36.44 ± 5.81 days after it. A corneal ET map was divided into 17 sectors with average values indicated, and 3 zones (the central zone of 2 mm, the paracentral zone from 2 to 5 mm, and the mid-peripheral zone from 5 to 6 mm). We calculated the maximum (Max) and the minimum (Min) values of ET, the difference between them (Max Min) in the 5 mm zone, and standard deviation of values in the 5 mm zone (Std Dev). Results. The corneal ET showed no difference among the sectors of the 6-mm map (p > 0.05) before OK lenses were worn. The ET in the central zone was 53.1 ± 1.68 μm. The ET in the central zone decreased by 16.6 % from the initial value after 36.44 ± 5.81 days of OK correction, with a single sector (S) showing a statistically significant difference in the paracentral zone. In the mid-peripheral zone, the ET increased by 14.1 % from the reference. Max and Min ET, and Max-Min Std Dev in the 5-mm zone differed significantly after OK correction (p < 0.05). Conclusion. After OK correction, the ET significantly decreases in the central zone and increases in the mid-peripheral zone. These changes account for the flattening of the anterior corneal surface and contribute to the refractive effect of OK lenses. For citations: Milash S.V., Tarutta E.P. Changes of corneal epithelial thickness before and after OK-correction according to SD-OCT. Russian ophthalmological journal. 2017; 10 (3): 49-54. doi: 10.21516/2072-0076-2017-10-3-49-54 (in Russian).
About the Authors
S. V. Milash
Moscow Helmholtz Research Institute of Eye Diseases
Russian Federation
Russian Federation
E. P. Tarutta
Moscow Helmholtz Research Institute of Eye Diseases
Russian Federation
Russian Federation
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Review
For citations:
Milash S.V., Tarutta E.P. Changes of corneal epithelial thickness before and after OK-correction according to SD-OCT. Russian Ophthalmological Journal. 2017;10(3):49-54. (In Russ.) https://doi.org/10.21516/2072-0076-2017-10-3-49-54
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