Preview

Russian Ophthalmological Journal

Advanced search

Visual and neurological complications of COVID-19

https://doi.org/10.21516/2072-0076-2023-16-2-173-176

Abstract

The review summarizes the evidence of visual and neurological complications in the acute stage of COVID-19 and in post-COVID syndrome. Neurological symptom complexes, and cerebrovascular disorders are described. Ophthalmologic manifestations may be a typical sign of COVID-19 onset, but they may also develop several weeks after recovery. The spectrum of neuro-ophthalmological manifestations in most cases includes optic neuritis, optic disc edema, optic neuropathy, and venous thrombosis. Ophthalmologists should be aware of the possible associations of ocular diseases with COVID-19 in order to diagnose and initiate an early treatment for life and vision threatening complications.

About the Authors

E. E. Ioileva
S. Fyodorov Eye Microsurgery National Medical Research Center
Russian Federation

Elena E. Ioileva, Dr. of Med. Sci., scientific secretary, principal researcher, department of therapeutical ophthalmology, 

59a, Beskudnikovsky Blvd, Moscow, 127486



A. Yu. Safonenko
S. Fyodorov Eye Microsurgery National Medical Research Center
Russian Federation

Alexandra Yu. Safonenko, Cand. of Med. Sci., ophthalmologist, lecturer, chair of eye diseases,

59a, Beskudnikovsky Blvd, Moscow, 127486



O. V. Golubeva
S. Fyodorov Eye Microsurgery National Medical Research Center
Russian Federation

Olesja V. Golubeva, Cand. of Med. Sci., ophthalmologist, lecturer, chair of eye diseases

59a, Beskudnikovsky Blvd, Moscow, 127486



K. N. Bolbachan
S. Fyodorov Eye Microsurgery National Medical Research Center
Russian Federation

Kiril N. Bolbachan, resident doctor,

59a, Beskudnikovsky Blvd, Moscow, 127486



References

1. The current epidemic situation in Russia and the world. Rospotrebnadzor RF, FKUZ RosNIPCHI “Microb” (In Russ.). Available at: https://www.rospotrebnadzor.ru/region/korono_virus/epid.php (Accessed 14 April 2023)

2. Baig AM, Khaleeq A, Ali U, Syeda H. Evidence of the COVID-19 virus targeting the CNS: Tissue distribution, host-virus interaction, and proposed neurotropic mechanisms. ACS Chem Neurosci. 2020; 11 (7): 995–8. doi: 10.1021/acschemneuro.0c00122

3. Romero-Sánchez CM, Díaz-Maroto I, Fernández-Díaz E, et al. Neurologic manifestations in hospitalized patients with COVID-19: The ALBACOVID registry. Neurology. 2020; 95 (8): e 1060–70. doi: 10.1212/WNL.0000000000009937

4. Siddiqi HK, Mehra MR. COVID-19 illness in native and immunosuppressed states: A clinical-therapeutic staging proposal. J Heart Lung Transplant. 2020; 39 (5): 405–7. doi: 10.1016/j.healun.2020.03.012

5. Pinna P, Grewal P, Julianne P, et al. Neurological manifestations and COVID-19: experiences from a tertiary care center at the frontline, Journal of the Neurological Sciences. J Neurol Sci. 2020; 415: 116969. doi: 10.1016/j.jns.2020.116969

6. Gutiérrez-Ortiz C, Méndez-Guerrero A, Rodrigo-Rey S, et al. Miller Fisher syndrome and polyneuritis cranialis in COVID-19. Neurology. 2020, 95 (5): e 601–5. doi: 10.1212/WNL.0000000000009619

7. Dinkin M, Gao V, Kahan J, et al. COVID-19 presenting with ophthalmoparesis from cranial nerve palsy. Neurology. 2020; 95 (5). 221–3. doi: 10.1212/WNL.0000000000009700

8. Paniz-Mondolfi A, Bryce C, Grimes Z, et al. Central nervous system involvement by severe acute respiratory syndrome coronavirus-2 (SARSCoV-2). J Med Virol. 2020; 92 (7): 699–702. doi: 10.1002/jmv.25915

9. Burgos-Blasco B, Güemes-Villahoz N, Donate-Lopez J, Vidal-Villegas B., García-Feijóo J. Optic nerve analysis in COVID-19 patients. J Med Virol. 2020; 93 (1): 190–1. doi: 10.1002/jmv.26290

10. Sen M, Honavar SG, Sharma N, Sachdev M. COVID-19 and eye: A review of ophthalmic manifestations of COVID-19. Indian J Ophthalmol. 2021; 69 (3): 488–509. doi: 10.4103/ijo.IJO_297_21

11. Golabchi K, Rezaee A, Aghadoost D, Hashemipour M. Anterior ischemic optic neuropathy as a rare manifestation of COVID-19: a case report. Fature Virol. 2022. doi: 10.2217/fvl-2021-0068

12. Cavalcanti DD, Raz E, Shapiro M, et al. Cerebral venous thrombosis associated with COVID-19. AJNR Am J Neuroradiol. 2020, 41 (8): 1370–6. doi: https://doi.org/10.3174/ajnr.A6644

13. Shakibajahromi B, Borhani-Haghighi A, Haseli S, et al. Cerebral venous sinus thrombosis might be under-diagnosed in the COVID-19 era. eNeurologicalSci. 2020; 20 (4): 100256. doi: 10.1016/j.ensci.2020.100256

14. Krivosheeva M.S., Ioileva E.E. Microcirculatory changes in the retina in the new coronavirus infection COVID-19. Russian pediatric ophthalmology. 2021; 2: 46–9 (In Russ.). doi: https://doi.org/10.25276/2307-6658-2021-2-46-49

15. Sawalha K, Adeodokun S, Kamoga GR. COVID-19-induced acute bilateral optic neuritis. J Invest Med High Impact Case Rep. 2020; 8: 232470962097601. doi: 10.1177/2324709620976018

16. Žorić L, Rajović-Mrkić I, Čolak E, Mirić D, Kisić B. Optic neuritis in a patient with seropositive myelin oligodendrocyte glycoprotein antibody during the post-COVID-19 period. Int Med Case Rep J. 2021; 14: 349–55. doi: 10.2147/IMCRJ.S315103

17. Azab MA, Hasaneen SF, Hanifa H, Azzam AY. Optic neuritis post-COVID-19 infection. A case report with meta-analysis. Interdiscup Neurosurg. 2021; 26: 101320. doi: 10.1016/j.inat.2021.101320

18. Tisdale AK, Chwalisz BK Neuro-ophthalmic manifestations of coronavirus disease 19. Curr Opin Ophthalmol. 2020; 31 (6): 489–94. doi: 10.1097/ICU.0000000000000707

19. Jossy A, Jacob N, Sarkar S, et al. COVID-19-associated optic neuritis — a case series and review of literature. Indian J Ophthalmol. 2022; 70 (1): 310–6. doi: 10.4103/ijo.IJO_2235_21

20. Insausti-García A, Reche-Sainz JA, Ruiz-Arranz C, Vázquez AL, FerroOsuna M. Papillophlebitis in a COVID-19 patient: Inflammation and hypercoagulable state. Eur J Ophthalmol. 2020; 32 (3): NP 168-NP 172. doi: 10.1177/1120672120947591


Review

For citations:


Ioileva E.E., Safonenko A.Yu., Golubeva O.V., Bolbachan K.N. Visual and neurological complications of COVID-19. Russian Ophthalmological Journal. 2023;16(2):173-176. (In Russ.) https://doi.org/10.21516/2072-0076-2023-16-2-173-176

Views: 597


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2072-0076 (Print)
ISSN 2587-5760 (Online)