Модифицирующее лечение дегенеративных заболеваний сетчатки. Часть 2. Методы кондиционирующей терапии и проблемы максимизации пластичности сетчатки

В первой части обзора [РОЖ, 2023; 16 (2): 160–2] обсуждались общие признаки и специфические особенности адаптивной и неадаптивной ретинальной пластичности, характеризующие такие заболевания, как глаукома, возрастная макулярная дегенерация, пигментный ретинит, диабетическая ретинопатия и ретинопатия недоношенных. В этой части обзора обсуждаются проблемы регенерации аксонов ганглиозных клеток сетчатки и анализируются терапевтические подходы, направленные на максимизацию пластичности и стимулирование репаративных способностей сетчатки. Обсуждаются защитные эффекты «кондиционирующих» стимулов в модифицирующем лечении заболеваний сетчатки. Представлены некоторые современные стратегии зрительной реабилитации, основанные на тренировках зрительной перцепции и зрительной фиксации с использованием систем с биологической обратной связью.

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