Preview

Russian Ophthalmological Journal

Advanced search

Results of surgical treatment of acute retinal necrosis

https://doi.org/10.21516/2072-0076-2018-11-1-5-11

Abstract

Purpose: to evaluate the effectiveness of surgical treatment of acute retinal necrosis. Material and methods. The study involves 34 patients aged 18 to 74 with acute retinal necrosis. Surgeries were performed on 41 eyes. All patients received microinvasive (23 Ga) vitrectomy with membrane peeling, endolaser coagulation of the retina and endotamponade of the vitreal cavity with silicone oil. Operated eyes were divided into 3 groups. Group 1 included 25 eyes which had retinal detachment and vitreous fibrosis at the time of surgical treatment. Group 2 consisted of 9 eyes with retinal detachment but no vitreous fibrosis, and group 3 of 7 eyes with vitreous fibrosis and no retinal detachment. Prior to surgery, visual acuity varied from wrong light perception up to 0.15 with correction. Results. A stable anatomical and optical result was achieved in all cases, complete attachment of the detached retina amounted to 94.1 %, and partial attachment to 5.9 % of the eyes. In group 1, improved visual acuity was observed in 56 % of cases, whereby visual acuity of 0.1 or higher was obtained only in 24 % of the eyes. In groups 2 and 3, visual acuity improved in all cases and proved to be 0.1 or higher, which was due to the predominance of the peripheral necrotic lesion zone, as well as to lower frequency of macular edema and optical neuropathy. In retinal detachment with vitreous fibrosis, a high frequency (72 %) of necrosis spread to the posterior pole of the eye with irreversible damage to the macula and optic nerve was detected. Conclusion. Modern technologies of surgical treatment allow achieving good anatomical results in all patients with acute retinal necrosis. The highest functional results are achieved with peripheral or paracentral lesions, absence of macular edema and optical neuropathy, and macula affected by retinal detachment prior to surgery, which was observed in groups with isolated vitreous fibrosis or retinal detachment. For citation: Neroev V.V., Ilyukhin P.A., Fedotov R.A., Tankovsky V.E. Results of surgical treatment of acute retinal necrosis. Russian ophthalmological journal. 2018; 11 (1): 5-11. doi: 10.21516/2072-0076-2018-11-1-5-11 (In Russian).

About the Authors

V. V. Neroev
Moscow Helmholtz Research Institute of Eye Diseases
Russian Federation


P. A. Ilyukhin
Moscow Helmholtz Research Institute of Eye Diseases
Russian Federation


R. A. Fedotov
Moscow Helmholtz Research Institute of Eye Diseases
Russian Federation


V. E. Tankovsky
Moscow Helmholtz Research Institute of Eye Diseases
Russian Federation


References

1. Muthiah M.N., Michaelides M., Child C.S., Mitchell S.M. Acute retinal necrosis: a national population-based study to assess the incidence, methods of diagnosis, treatment strategies and outcomes in the UK. Br. J. Ophthalmol. 2007; 91(11): 1452-5. doi:10.1136/bjo.2007.114884

2. Rautenberg P., Grancicova L., Hillenkamp J. Acute retinal necrosis from the virologist's perspective. Ophthalmologe. 2009; 106(12 Dec.): 1065-73. doi:10.1007/s00347-009-2048-4

3. Neroev V., Tankovskiy V., Krichevskaia G. Serological evaluation of the immune status of patients with acute retinal necrosis. In: 9th International Symposium on Uveitis. Dublin; 2016: 81-2.

4. Holland G.N. Standard diagnostic criteria for the acute retinal necrosis syndrome. Executive Committee of the American Uveitis Society. Am. J. Ophthalmol. 1994; 117: 663-7. doi: http://dx.doi.org/10.1016/S0002-9394(14)70075-3

5. Gartry D.S., Spalton D.J., Tilzey A., Hykin P.G. Acute retinal necrosis syndrome. Br. J. Ophthalmol. 1991; 75(5 May): 292-7. doi: http://dx.doi.org/10.1136/bjo.75.5.292

6. Martenet A. “Necrose” retinienne peripherique et decollement retinien total d’origine vasculaire. In: 5th Congress Soc. Europ. Ophtal. Hambourg. 1976; Enke, Stuttgart. 1978: 180-2.

7. Young N.J., Bird A.C. Bilateral acute retinal necrosis. Br. J. Ophthalmol. 1978; 62(9 Sep.): 581-90. doi: http://dx.doi.org/10.1136/bjo.62.9.581

8. Culbertson W.W., Blumenkranz M.S., Haines H. The acute retinal necrosis syndrome. Part 2: Histopathology and etiology. Ophthalmology. 1982; 89 (12 Dec.): 1317-25. doi: http://dx.doi.org/10.1016/S0161-6420(82)34638-2

9. Culbertson W.W., Blumenkranz M.S., Pepose J.S., Stewart J.A., Curtin V.T. Varicella zoster virus is a cause of the acute retinal necrosis syndrome. Ophthalmology. 1986; 93(5 May): 559-69. doi: http://dx.doi.org/10.1016/S0161-6420(86)33701-1

10. Schoenberger S.D., Kim S.J., Thorne J.E., Mruthyunjaya P. Diagnosis and treatment of acute retinal necrosis: a report by the American Academy of Ophthalmology. Ophthalmology. 2017; 124(3 Mar.): 382-92. doi:10.1016/j.ophtha.2016.11.007

11. Biron K.K. Antiviral drugs for cytomegalovirus diseases. Antiviral Res. 2006; 71 (2-3 Sep.): 154-63. doi: 10.1016/j.antiviral.2006.05.002

12. Денисова Е.В., Катаргина Л.А., Кричевская Г.И., Гвоздюк Н.А., Старикова А.В. Острый ретинальный некроз у детей: клинические проявления и результаты лечения. Российская педиатрическая офтальмология. 2015; 2: 53-5.

13. Berker N., Ozdal P., Batman C., Soykan E. Prophylactic vitrectomy in acute retinal necrosis syndrome. Eye (Lond). 2007; 21: 104-6. doi: 10.1038/sj.eye.6702410

14. Hillenkamp J., Nolle B., Bruns C. Acute retinal necrosis: clinical features, early vitrectomy, and outcomes. Ophthalmology. 2009; 116: 1971-5. doi: 10.1016/j.ophtha.2009.03.029.

15. Ishida T., Sugamoto Y., Sugita S., Mochizuki M. Prophylactic vitrectomy for acute retinal necrosis. Jpn. J. Ophthalmol. 2009; 53: 486-489. doi: 10.1007/s10384-009-0698-z

16. Luo Y.H., Duan X.C., Chen B.H., Tang L.S., Guo X.J. Efficacy and necessity of prophylactic vitrectomy for acute retinal necrosis syndrome. Int. J. Ophthalmol. 2012; 5(4): 482-7. doi: 10.3980/j.issn.2222-3959.2012.04.15

17. Matsuo T. Timing of prophylactic and early vitrectomy for first-presenting or recurrent acute retinal necrosis syndrome. Acta Med. Okayama, 2012; 66(6): 493-7. doi: 10.18926/AMO/49046

18. Navarro-Navarro A., Martinez-Toldos J.J. Presumed bilateral acute retinal necrosis 11 years apart, atypical presentation, and early vitrectomy. Eur. J. Ophthalmol. 2015; 30; 25(5): e 81-3. doi: 10.5301/ejo.5000596

19. Holland G.N., Buhles W.C. Jr, Mastre B., Kaplan H.J. A controlled retrospective study of ganciclovir treatment for cytomegalovirus retinopathy. Use of a standardized system for the assessment of disease outcome. UCLA CMV Retinopathy. Study Group. Arch. Ophthalmol. 1989; 107(12 Dec.): 1759-66. doi:10.1001/archopht.1989.01070020841024


Review

For citations:


Neroev V.V., Ilyukhin P.A., Fedotov R.A., Tankovsky V.E. Results of surgical treatment of acute retinal necrosis. Russian Ophthalmological Journal. 2018;11(1):5-11. (In Russ.) https://doi.org/10.21516/2072-0076-2018-11-1-5-11

Views: 912


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2072-0076 (Print)
ISSN 2587-5760 (Online)