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Clinical case of bleb ossification in uveal melanoma

https://doi.org/10.21516/2072-0076-2025-18-2-140-145

Abstract

We present a clinical case of untimely recognized and inadequately treated iris melanoma, which led to the development of secondary hypertension and secondary cataract in the absence of extrabulbar growth and the presence of bleb ossification during 6 months after trabeculectomy against the background of uveal melanoma. Ossification was not accompanied by an inflammatory reaction and allowed the surgically created a well function filtering bleb. The case confirms the need for a full examination of patients and for increasing the specialists level of oncological alertness.

About the Authors

S. V. Saakyan
Helmholtz National Medical Research Center of Eye Diseases; A.I. Evdokimov Moscow State University of Medicine and Dentistry
Russian Federation

Svetlana V. Saakyan — corresponding member of RAS, Dr. of Med. Sci., professor, head of ocular oncology and radiology department, Helmholtz National Medical Research Center of Eye Diseases; deputy director of education, chair of ophthalmology, A.I. Evdokimov Moscow State University of Medicine and Dentistry.

14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062; 20, Bldg.1, Delegatskaya St., Moscow, 127473



N. S. Izmailova
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation

Natalia S. Izmailova — head of the department of pathological fnatomy and histology, leading researcher, pathologist.

14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062



S. Yu. Petrov
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation

Sergey Yu. Petrov — Dr. of Med. Sci., head of glaucoma department.

14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062



V. R. Alikhanova
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation

Valida R. Alikhanova — Cand. of Med. Sci., ophthalmologist, ocular oncology and radiology department.

14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062



A. A. Zharov
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation

Andrey A. Zharov — researcher at the department of pathological anatomy and histology, pathologist.

14/19, Sadovaya-Chernogryazskaya St., Moscow, 105062



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Review

For citations:


Saakyan S.V., Izmailova N.S., Petrov S.Yu., Alikhanova V.R., Zharov A.A. Clinical case of bleb ossification in uveal melanoma. Russian Ophthalmological Journal. 2025;18(2):140-145. (In Russ.) https://doi.org/10.21516/2072-0076-2025-18-2-140-145

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ISSN 2072-0076 (Print)
ISSN 2587-5760 (Online)