Biomechanical parameters of the eye fibrous capsule in pigment dispersion syndrome and pigmentary glaucoma and their changes after peripheral iridectomy
https://doi.org/10.21516/2072-0076-2025-18-2-62-68
Abstract
Purpose of the work was to study the features of biomechanical properties of the fibrous capsule of the eye in pigment dispersion syndrome (PDS) and pigment glaucoma (PG), and to evaluate the effect of peripheral iridectomy (PIE) in these conditions on the biomechanics of the eye. Material and methods. Biomechanical parameters of 45 eyes of 23 patients with PDS (26 eyes) and PG (19 eyes) aged 33.6 ± 1.5 years were compared. Keratorefractive surgery (Femto Super LASIK) was performed on 5 eyes of patients in this group. PIE was performed on 34 eyes with PDS and PG. The examination also included 30 eyes with myopia without PDS and PG aged 40.2 ± 1.8 years (comparison group) and 18 eyes of patients with emmetropia without glaucoma aged 37.00 ± 1.93 years (control group). Biomechanical parameters and biomechanically corrected IOP (bIOP) were determined using Pentacam (Oculus) and CorVis ST. Results. Eyes with SPD and PG did not significantly differ in biomechanical parameters from myopic eyes without SPD and PG. At the same time, the biomechanical glaucoma factor (BGF) in SPD and PG was lower than in myopia (p = 0.025 and p = 0.015), which indirectly characterizes the fibrous membrane of the eyes with SPD and PG as more rigid. SSI (an indicator of internal corneal rigidity) of the eyes with SPD, PG and myopia was reduced in comparison with healthy emmetropic eyes (p = 0.000, p = 0.019, p = 0.005, respectively). After the PIE, the bIOP level decreased (p = 0.015), the values of corneal rigidity characteristics changed: Integr. Radius increased (p = 0.002) and the SP-A1 index decreased (p = 0.022), which indicates a decrease in corneal tissue rigidity. At the same time, BGF increased (p = 0.026) and reached the corresponding values of myopic eyes without SPD and PG. Conclusion. Taking into account the reduced SSI index, keratorefractive intervention in SPD and PG should be performed with caution. PIE in SPD and PG can be recommended not only to reduce IOP, but also to normalize biomechanics indicators and bring their values closer to the parameters of a myopic eyes without SPD and PG.
Keywords
About the Authors
A. V. MalyshevRussian Federation
Alexey V. Malyshev — Dr. of Med. Sci., professor, head of chair of ophthalmology, Maykop State Technological University; head of ophthalmology department, Scientific Research Institution — S.V. Ochapovsky Regional Clinic Hospital No. 1.
19, Pervomaiskaya St., Maykop, Adygea Republic, 385000; 167, 1 May St., Krasnodar, 350086
A. S. Apostolova
Russian Federation
Anastasia S. Apostolova — Cand. of Med. Sci., аssistant professor, chair of ophthalmology, Maykop State Technological University; ophthalmologist, glaucoma specialist, Vision care clinic ”3Z”.
19, Pervomaiskaya St., Maykop, Adygea Republic, 385000; 18, Krasnykh Partizan St., Krasnodar, 350047
A. A. Sergienko
Russian Federation
Aleksey A. Sergienko — Cand. of Med. Sci., аssistant professor, chair of ophthalmology, Maykop State Technological University; ophthalmologist, Children's Regional Clinical Hospital.
19, Pervomaiskaya St., Maykop, Adygea Republic, 385000; 1, Pobedy Square, Krasnodar, 350007
A. F. Teshev
Russian Federation
Adam F. Teshev — аssistant professor, chair of ophthalmology, Maykop State Technological University; head of the ophthalmology department, Adygean Republican Clinical Hospital of the Republic of Adygea.
19, Pervomaiskaya St., Maykop, Adygea Republic, 385000; 4, Zhukovsky St., Maikop, 385000
G. Yu. Karapetov
Russian Federation
Garry Yu. Karapetov — Cand. of Med. Sci., аssistant professor, chair of ophthalmology, Maykop State Technological University; ophthalmologist, Scientific Research Institution — S.V. Ochapovsky Regional Clinic Hospital No. 1.
19, Pervomaiskaya St., Maykop, Adygea Republic, 385000; 167, 1 May St., Krasnodar, 350086
M. K. Ashkhamakhova
Russian Federation
Marina K. Ashkhamakhova — аssistant professor, chair of ophthalmology, Maykop State Technological University; ophthalmologist, Adygean Republican Clinical Hospital of the Republic of Adygea.
19, Pervomaiskaya St., Maykop, Adygea Republic, 385000; 4, Zhukovsky St., Maikop, 385000
B. N. Hatsukova
Russian Federation
Bella N. Hatsukova — аssistant professor, chair of ophthalmology, Maykop State Technological University; ophthalmologist, Adygean Republican Clinical Hospital of the Republic of Adygea.
19, Pervomaiskaya St., Maykop, Adygea Republic, 385000; 4, Zhukovsky St., Maikop, 385000
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Review
For citations:
Malyshev A.V., Apostolova A.S., Sergienko A.A., Teshev A.F., Karapetov G.Yu., Ashkhamakhova M.K., Hatsukova B.N. Biomechanical parameters of the eye fibrous capsule in pigment dispersion syndrome and pigmentary glaucoma and their changes after peripheral iridectomy. Russian Ophthalmological Journal. 2025;18(2):62-68. (In Russ.) https://doi.org/10.21516/2072-0076-2025-18-2-62-68