A clinical case of choroidal melanoma recurrence in the orbit 14 years after enucleation
E. B. Myakoshina,
S. V. Saakyan,
A. Yu. Tsygankov,
M. P. Kharlampidi,
N. F. Musova,
S. Yu. Nechesnyuk https://doi.org/10.21516/2072-0076-2025-18-4-139-143
Abstract
Uveal melanoma is a multifactorial malignant intraocular tumor of neuroectodermal genesis, developing from melanocytes of the uveal tract, characterized by a high risk of metastasis and a poor vital prognosis. The paper describes the clinical observation of a 67-year-old patient with a late recurrence of choroidal melanoma in orbit in 2024 after enucleation in 2010. Clinically, echographically, and according to computer tomography, the presence of a neoplasm in the orbit has been confirmed. The patient underwent a transconjunctival orbitotomy, and a dark brown pseudocapsule about 2 cm in size was removed. According to the pathohistological conclusion, the morphological picture of the neoplasm of the left orbit corresponded to a recurrence of melanoma with the presence of perineural invasion. The patient is directed to irradiate the left orbit with a narrow medical proton beam. Despite the rarity, such a case demonstrates the need for lifelong monitoring of patients with choroidal melanoma, regardless of the time after surgical treatment, in order to timely identify and treat local and long-term complications.
About the Authors
E. B. Myakoshina
Helmholtz National Medical Research Center of Eye Diseases;
Russian University of Medicine
Russian Federation
Russian Federation
Elena B. Myakoshina — Dr. of Med. Sci., senior researcher, ocular oncology and radiology department, Helmholtz National Medical Research Center of Eye Diseases, associate professor of chair of eye diseases, Russian University of Medicine
14/19, Sadovaya-Chernogryazskaya st., Moscow, 105062,
2 Russian University of Medicine, 4, Dolgorukovskaya St., Moscow, 127006
S. V. Saakyan
Helmholtz National Medical Research Center of Eye Diseases;
Russian University of Medicine
Russian Federation
Russian Federation
Svetlana V. Saakyan — сorresponding member of RAS, Dr. of Med. Sci., professor, head of ocular oncology and radiology department, Helmholtz National Medical Research Center of Eye Diseases, deputy director of education, chair of eye disease, Russian University of Medicine
14/19, Sadovaya-Chernogryazskaya st., Moscow, 105062,
2 Russian University of Medicine, 4, Dolgorukovskaya St., Moscow, 127006
A. Yu. Tsygankov
Helmholtz National Medical Research Center of Eye Diseases;
Russian University of Medicine
Russian Federation
Russian Federation
Alexander Yu. Tsygankov — Cand. of Med. Sci., researcher at ocular oncology and radiology department, Helmholtz National Medical Research Center of Eye Diseases, assistant, chair of ophthalmology, Russian University of Medicine
14/19, Sadovaya-Chernogryazskaya st., Moscow, 105062,
2 Russian University of Medicine, 4, Dolgorukovskaya St., Moscow, 127006
M. P. Kharlampidi
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation
Russian Federation
Marina P. Kharlampidi — Cand. of Med. Sci., head doctor
14/19, Sadovaya-Chernogryazskaya st., Moscow, 105062
N. F. Musova
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation
Russian Federation
Nelly F. Musova — ophthalmologist, adult out-patient department
14/19, Sadovaya-Chernogryazskaya st., Moscow, 105062
S. Yu. Nechesnyuk
Helmholtz National Medical Research Center of Eye Diseases
Russian Federation
Russian Federation
Svetlana Yu. Nechesnyuk — Cand. of Med. Sci., head of pathological anatomy and histology unit
14/19, Sadovaya-Chernogryazskaya st., Moscow, 105062
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Review
For citations:
Myakoshina E.B., Saakyan S.V., Tsygankov A.Yu., Kharlampidi M.P., Musova N.F., Nechesnyuk S.Yu. A clinical case of choroidal melanoma recurrence in the orbit 14 years after enucleation. Russian Ophthalmological Journal. 2025;18(4):139-143. (In Russ.) https://doi.org/10.21516/2072-0076-2025-18-4-139-143
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