Functional express testing and self monitoring in the diagnosis and treatment of macular diseases

Abstract

The paper focuses on the diagnostic value of 3D-CTAG in express testing and dynamic self monitoring of treatment of macular diseases. We examined 165 patients (244 eyes) divided into 5 groups: group 1 - 92 patients with dry AMD; group 2 - 43 patients with wet AMD; group 3 - 28 patients with a fibrous scar; group 4 - 31 patients with diabetic macular edema and group 5 of 50 patients who served as control. The standard examination of all patients were supplemented by 3D-computer threshold Amsler grid test (3D-CTAG), microperimetry, optical coherent tomography (OCT), and fluorescent angiography (upon indication). The treatment depended on the clinical form of the disease: multivitamins with Lutein and Zeaxanthin, metabolic agents, or inhibitors of vascular endothelial growth factor. The study shows that 3D-CTAG with an improved protocol can be effectively used as a rapid method of detecting disorders of the macular area depending on the type and duration of the disease. Clinical and functional parallels revealed between the changes in 3D-CTAG and the size of CNV corresponded to a change in brightness sensitivity seen in microperimetry and were confirmed by OCT and fluorescent angiography. // Russian Ophthalmological Journal, 2016; 2: 48-54 . doi: 10.21516/2072-0076-2016-9-2-48-54 .