Etiopathogenetic therapy effect on the microcirculation of the bulbar conjunctiva in patients with dyslipidemia after COVID-19 associated pneumonia
https://doi.org/10.21516/2072-0076-2021-14-2-7-13
Abstract
Purpose:to study the hemodynamics of the bulbar conjunctiva in patients with dyslipidemia and a history of COVID-19 associated pneumonia who received etiopathogenetic therapy. Material and methods. 54 patients (108 eyes) aged 61 ± 14 with a documented diagnosis of COVID-19-associated pneumonia and dyslipidemia were prospectively examined 3 months after the discharge from hospital. Patients were divided into two groups, identical in gender and age, depending on the presence or absence of metabolic syndrome. For 1 month, both groups received etiotropic therapy: statins, antioxidants thioctic acid pills and topical antioxidant instillations (1 % solution of Emoxipine®three times a day, and instillations of NSAID Broxinac®(in the form of 0.09 % Bromfenacum eyedrops) 1 drop 2 times a day. Results.Improvement was achieved in perivascular parameters (of 54 % of patients of group 1 and 50 % of patients of group 2); in the shape of bloodvessels (in 10 and 11 % of cases, respectively); intravascular parameters (in 71 and 78 %, respectively). Conclusion. The proposed etiopathogenetic therapy has a positive effect on the state of damaged bulbar conjunctiva microcirculation.
About the Authors
E. N. Kalyuzhnaya
Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Russian Academy of Science; Tyumen State Medical University, Institute of Continuous Professional Development
Russian Federation
Russian Federation
Elena N. Kalyuzhnaya— laboratory assistant-researcher of the
department of arterial hypertension and coronary insufficiency of the scientific department of clinical cardiology, post-graduate student of the Department of Surgical Diseases with courses in Endoscopy and Ophthalmology
111, Melnikaite St., Tyumen, 625026
54, Odesskaya St., Tyumen, 625023
M.N N. Ponomareva
Tyumen State Medical University, Institute of Continuous Professional Development
Russian Federation
Russian Federation
Maria N. Ponomareva — Dr. of Med. Sci., associate professor, professor of the department of surgical diseases with courses of endoscopy and ophthalmology
54, Odesskaya St., Tyumen, 625023
I. M. Petrov
Tyumen State Medical University, Institute of Continuous Professional Development
Russian Federation
Russian Federation
Ivan M. Petrov — Dr. of Med. Sci., associate professor, head of the
department of medical informatics and biological physics with the
UNESCO bioethics network section
54, Odesskaya St., Tyumen, 625023
D. A. Karpova
Tyumen State Medical University, Institute of Continuous Professional Development
Russian Federation
Russian Federation
Darya A. Karpova — clinical resident of the department of surgical diseases with courses in endoscopy and ophthalmology
54, Odesskaya St., Tyumen, 625023
L. I. Gapon
Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Russian Academy of Science
Russian Federation
Russian Federation
Lyudmila I. Gapon — Dr. of Med. Sci., professor, head of the scientific department of clinical cardiology
111, Melnikaite St., Tyumen, 625026
T. I. Petelina
Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Russian Academy of Science
Russian Federation
Russian Federation
Tatyana I. Petelina— Dr. of Med. Sci., leading researcher of the
department of arterial hypertension and coronary insufficiency of the scientific department of clinical cardiology (SDCC), head of the laboratory of clinical diagnostic and molecular-genetic research of SDCC, deputy director for scientific work
111, Melnikaite St., Tyumen, 625026
E. I. Yaroslavskaya
Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Russian Academy of Science
Russian Federation
Russian Federation
Elena I. Yaroslavskaya— Dr. of Med. Sci., leading researcher of the
laboratory of instrumental diagnostics of the scientific department of instrumental research methods (LID SDIRM), head of the LID SDIRM
111, Melnikaite St., Tyumen, 625026
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Review
For citations:
Kalyuzhnaya E.N., Ponomareva M.N., Petrov I.M., Karpova D.A., Gapon L.I., Petelina T.I., Yaroslavskaya E.I. Etiopathogenetic therapy effect on the microcirculation of the bulbar conjunctiva in patients with dyslipidemia after COVID-19 associated pneumonia. Russian Ophthalmological Journal. 2021;14(2):7-13. (In Russ.) https://doi.org/10.21516/2072-0076-2021-14-2-7-13
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