The effectiveness of ozone therapy in the treatment of herpetic uveitis
https://doi.org/10.21516/2072-0076-2017-10-2-23-27
Abstract
Purpose: to study the clinical effectiveness of ozone therapy in the treatment of herpetic uveitis. Material and methods.41 patients with herpetic uveitis aged 21 to 69 (40.3 ± 11.5) years were followed. 21 patients (21 eyes) comprised the experimental group, which received traditional treatment in combination with ozone therapy, and 20 patients (20 eyes) comprised the control group who only received conventional drug therapy. Results. The resorption of choroid infiltration took 21.4 ± 0.2 days in the experimental group and 24.8 ± 0.1 days in the control group (p < 0.05). Visual acuity averagely increased from 0.04 ± 0.02 to 0.61 ± 0.09 in the experimental group and from 0.08 ± 0.03 to 0.54 ± 0.08, in the control group (p> 0.05). The total treatment duration was, respectively 22.1 ± 0.1 and 25.9 ± 0.5 days, p < 0.05). The treatment effectiveness can be assessed as follows; in the experimental group, the recovery could be established in 19 patients (90.5 %) and condition improvement in 2 patients (9.5 %). In the control group, the recovery was noted in 14 patients (70 %) and 6 patients (30 %) showed an improvement. Conclusion. To achieve an optimal effect, patients with herpetic uveitis should be treated with ozone therapy in addition to regular antiherpetic treatment // Russian ophthalmological journal. 2017; 10 (2): 23-7. doi: 10.21516/2072-0076-2017-10-2-23-27.
About the Author
M. G. Guliyeva
National Centre of Ophthalmology named after Acad. Zarifa Aliyeva, Ministry of Health of Azerbaijan Republic, Baku, Azerbaijan
Russian Federation
Russian Federation
References
1. Катаргина Л.А., Архипова Л.Т. Увеиты: патогенетическая иммуносупрессивная терапия. Тверь: ООО Издательство «Триада»; 2004: 4-5.
2. Сенченко Н.Я., Щуко А.Г., Малышев В.В. Увеиты. Москва: ГЕОТАР-Медиа; 2010. Senchenko N.I., Schuko A.G., Malyshev V.V. The uveitis. Moscow: GEOTAR - Media; 2010, p. 69 (in Russian).
3. Кацнельсон Л.А., Танковский В.Э. Увеиты (клиника, лечение). Изд. 2-е, переработанное. Москва: 4 филиал Воениздата; 2003: 192-7.
4. Нероев В.В., Катаргина Л.А., Денисова Е.В., Мешкова Г.И., Гвоздюк Н.А. Состояние и функции макулы при периферических увеитах у детей и подростков. Российский офтальмологический журнал. 2009; 2 (1): 21-7.
5. Biswas P.S., Rouse B.T. Early events in HSV keratitis - setting the stage for a blinding disease. Microbes-Infect. 2005 Apr; 7 (4): 799-810.
6. Crooks R. J., Murray A. Valaciclovir - a review of a promising new antiherpes agent. Antiviral Chemistry Chemotherapy. 1994; 5: 31-7.
7. Пасечникова Н.В., Зборовская А.В., Яковенко Т.А. Инфекционные задние увеиты. Киев: Читверта хвиля. 2005: 14-9.
8. Kaufman H-E. Can we prevent recurrences of herpes infections without antiviral drugs? Invest Ophthalmol Vis Sci. 2002; 43 (5): 1325-9.
9. Wilhelmus K.R. Interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev. 2003; 3: CD002898.
10. Wu X., Chen X. Acyclovir for the treatment and prevention of recurrent infectious herpes simplex keratitis. Chinese Medical Journal. 2002; 115 (10): 1569-72.
11. Bocci V.A. Scientific and medical aspects of ozone therapy. State of the art. Archives of Medical Research. 2006; 37 (4): 425-35.
12. Re L., Mawsouf M.N., Menéndez S., et al. Ozone therapy: clinical and basic evidence of its therapeutic potential. Arch Med Res. 2008 Jan; 39 (1): 17-26.
13. American Cancer Society. Pharmacological and Biological Treatment: Oxygen Therapy. Available at: http://www.cancer.org/ Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/ PharmacologicalandBiologicalTreatment/ Accessed: 20th August 2012.
14. Magalhaes F.N., Dotta L., Sasse A., Teixera M.J., Fonoff E.T. Ozone therapy as a treatment for low back pain secondary to herniated disc: a systematic review and meta-analysis of randomized controlled trials. Pain Physician. 2012 Mar-Apr; 15 (2): E115-29.
15. Schulz S., Haussler U., Mandic R., et al. Treatment with ozone/ oxygen-pneumoperitoneum results in complete remission of rabbit squamous cell carcinomas. Int J Cancer. 2008; 122 (10): 2360-7.
Review
For citations:
Guliyeva M.G. The effectiveness of ozone therapy in the treatment of herpetic uveitis. Russian Ophthalmological Journal. 2017;10(2):23-27. (In Russ.) https://doi.org/10.21516/2072-0076-2017-10-2-23-27
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