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Perfusion of the iris after selective laser trabeculoplasty: optical coherent tomography angiography data

https://doi.org/10.21516/2072-0076-2022-15-2-supplement-93-97

Abstract

Purpose: to study iris perfusion in patients with primary open-angle glaucoma (POAG) after selective laser trabeculoplasty (SLT) using optical coherence tomography angiography (OCTA).

Material and methods. 12 patients aged 68.3 ± 8.4 with stage I to III POAG underwent a standard ophthalmic examination as well as OCTA examination of the iris, which was performed through the center of the pupil under photopic conditions using RTVue-XR with Angio Retina 3-mm protocol. All patients received examination before SLT, one day, seven days, and 30 days after SLT. Vascularity was determined with ImageJ as the total length of binarized and skeletonized vessels over the full thickness of the iris slab.

Results. A statistically significant correlation was found between the values of intraocular pressure (IOP) measured one month after SLT and iris vascularity before SLT, one day after SLT, and their difference. The strongest correlation (r = 0.60, p = 0.001) was found between iris vascularity one day after SLT and IOP one month after the procedure.

Conclusions. SLT is accompanied by an increase in iris vascularity, which fact may probably be used in the prediction of the final IOP in these patients.

About the Authors

D. S. Maltsev
S.M. Kirov Military Medical Academy
Russian Federation

Dmitry S. Maltsev — Dr. of Med. Sci, assistant professor; head of the unit of laser surgery of ophthalmology chair named after professor V.V. Volkov

6, Academician Lebedev St., St. Petersburg, 194044



A. A. Kazak
S.M. Kirov Military Medical Academy
Russian Federation

Alina A. Kazak — resident of ophthalmology chair named after professor V.V. Volkov

6, Academician Lebedev St., St. Petersburg, 194044



A. N. Kulikov
S.M. Kirov Military Medical Academy
Russian Federation

Alexey N. Kulikov — Dr. of Med. Sci, professor, head of chair named after professor V.V. Volkov

6, Academician Lebedev St., St. Petersburg, 194044



A. S. Vasilyev
S.M. Kirov Military Medical Academy
Russian Federation

Andrey S. Vasilev — ophthalmologist of ophthalmology chair named after professor V.V. Volkov

6, Academician Lebedev St., St. Petersburg, 194044



M. A. Burnasheva
S.M. Kirov Military Medical Academy
Russian Federation

Maria A. Burnasheva — ophthalmologist of ophthalmology chair named after professor V.V. Volkov

6, Academician Lebedev St., St. Petersburg, 194044



References

1. Thomas S., Hodge W., Malvankar-Mehta M. The cost-effectiveness analysis of teleglaucoma screening device. PLoS One. 2015; 10: 0. doi: 10.1371/journal. pone.0137913

2. McMonnies C.W. Glaucoma history and risk factors. J. Optom. 2017; 10: 71–8. doi:10.1016/j.optom.2016.02.003

3. Allison К., Patel D., Alabi O. Epidemiology of glaucoma: the past, present, and predictions for the future. Cureus. 2020 Nov; 12 (11). doi: 10.7759/cureus.11686

4. Tham Y.C., Li X., Wong T.Y., et al. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology. 2014; 121: 2081–90. doi: 10.1016/j. ophtha.2014.05.013

5. Nan Zhang, Jiaxing Wang, Ying Li, Bing Jiang. Prevalence of primary open angle glaucoma in the last 20 years: a meta-analysis and systematic review. Scientific Reports. 2021; 11: Article number:13762. doi: 10.3389/ fmed.2020.624179

6. Bikbov M.M., Babushkin A.E., Khusnitdinov I.I., Murova L. h., Matyukhina E.N. Dynamics of epidemiological indicators of glaucoma in the Republic of Bashkortostan for the period of 2010–2016. RMJ “Clinical ophthalmology”. 2018; 4: 163–7. doi: 10.21689/2311-7729-2018- 18-4-163-167

7. Heijl A., Leske M.C., Bengtsson B., Bengtsson B., Hussein M.; Early Manifest Glaucoma Trial Group. Measuring visual field progression in the Early Manifest Glaucoma Trial. Acta Ophthalmol. Scand. 2003; 81: 286–93. doi: 10.1034/j.1600-0420.2003.00070.x

8. Latina M.A., Park C. Selective targeting of trabecular meshwork cells: in vitro studies of pulsed and CW laser interactions. Exp. Eye Res. 1995 Apr; 60 (4): 359–71. doi: 10.1016/s0014-4835(05)80093-4

9. McAlinden С. Selective laser trabeculoplasty (SLT) vs other treatment modalities for glaucoma: systematic review. Nature Research. Eye. 2014 Mar; 28 (3): 249–58. doi: 10.1038/eye.2013.267

10. Wasyluk J. T., Piekarniak-Wo niak A., Grabska-Liberek I. The hypotensive effect of selective laser trabeculoplasty depending on iridocorneal angle pigmentation in primary open angle glaucoma patients. Arch. Med. Sci., 2014 May 12; 10 (2): 306–8. doi: 10.5114/aoms.2014.42583

11. Kulikov A.N., Maltsev D.S., Kazak A.A., Burnasheva M.A. Anterior chamber particles are associated with reduction of intraocular pressure after selective laser trabeculoplasty. Br. J. Ophthalmol. 2020 Nov; 104 (11): 1508–11. doi: 10.1136/bjophthalmol-2019-315445

12. De Keyser M., De Belder M., De Groot V. Randomized prospective study of the use of anti-inflammatory drops after selective laser trabeculoplasty. J. Glaucoma. 2017 Feb; 26 (2): 22–9. doi: 10.1097/ IJG.0000000000000522

13. Wong M.O., Lee J.W., Choy B.N., Chan J.C., Lai J.S. Systematic review and meta-analysis on the efficacy of selective laser trabeculoplasty in open-angle glaucoma. Surv. Ophthalmol. 2015 Jan-Feb; 60 (1): 36–50. doi: 10.1016/j. survophthal.2014.06.006


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For citations:


Maltsev D.S., Kazak A.A., Kulikov A.N., Vasilyev A.S., Burnasheva M.A. Perfusion of the iris after selective laser trabeculoplasty: optical coherent tomography angiography data. Russian Ophthalmological Journal. 2022;15(2 (Прил)):93-97. (In Russ.) https://doi.org/10.21516/2072-0076-2022-15-2-supplement-93-97

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ISSN 2072-0076 (Print)
ISSN 2587-5760 (Online)