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Clinical effectiveness of nutrof total supplement for Dry age-related macular Degeneration

https://doi.org/10.21516/2072-0076-2016-9-2-90-95

Abstract

The paper’s purpose is to assess visual functions in patients with dry age-related macular degeneration (AMD) who receive antioxidant Nutrof Total supplement. Three groups of patients over 50 were examined. The main group, AMD+, consisted of patients with dry AMD who took 1 capsule of the supplement once a day for 3 months. Control group 1, AMD-, was composed of patients with dry AMD who took no supplement at all and control group 2, Normal, was composed of healthy subjects who took 1 capsule once a day for 3 months. All subjects were subjected to a regular ophthalmologic examination supplemented by evaluation of photostress test recovery time, and measurement of the optical density of macular pigment (MPOD) and achromatic spatial contrast sensitivity (CS): all tests were taken prior to the study and repeated 1 and 3 months after the study’s start. Vision quality was assessed by a VFQ-25, 2000 version questionnaire. Groups AMD+ and Normal revealed a statistically significant improvement in uncorrected distance and near visual acuity and best-corrected distance visual acuity, MPOD increase, improved recovery of visual acuity after a photostress test, and improvement in achromatic CS in all spatial frequency ranges. AMD- patients revealed no positive effects of visual functions. The results of the study thus confirm the efficiency and usefulness of continuous Nutrof Total supplement administration for 3 months by dry AMD patients and all patients over 50 // Russian Ophthalmological Journal, 2016; 2: 90-5. doi: 10.21516/2072-0076-2016-9-2-90-95 .

About the Authors

E. N. Eskina
Laser surgery clinic "Sphere", Moscow, Russia
Russian Federation


A. V. Belogurova
Laser surgery clinic "Sphere", Moscow, Russia
Russian Federation


M. A. Stepanova
Laser surgery clinic "Sphere", Moscow, Russia
Russian Federation


References

1. SanGiovanni J.P., Chew E.Y., Clemons T.E., et al. The relationship of dietary carotenoids and vitamin A, E, And C intake with Age-Related Macular Degeneration in a case-control study: AREDS Report 22. Arch. Ophthalmol. 2007; 125(9): 1225-32.

2. Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, Beta carotene, and Zinc for Age-Related Macular Degeneration and vision loss: AREDS Report 8. Arch. Ophthalmol. 2001; 119(10): 1417-36.

3. Розанова О.И. Сенченкова Н.Я., Щуко А.Г., Малышев В.В. Характеристика зрительного восприятия пациентов с артифакией. В кн.: Катарактальная и рефракционная хирургия: сб. ст. Москва; 2008: 211-14.

4. Товкач В.И. Фотостресс обычным электроофтальмоскопом в диагностике заболеваний глаз. Военно-медицинский журнал. 1977; 8: 40-4.

5. Егоров Е.А., Эскина Э.Н., Гветадзе А.А. и др. Оценка повторяемости метода исследования оптической плотности макулярного пигмента (предварительные результаты). В кн.: XIV Всероссийская школа офтальмолога: сб. науч. тр. Москва; 2015: 141-5.

6. Stangos N., Voutas S., Topouzis F., Karampatakis V. Contrast sensitivity evaluation in eyes predisposed to age-related macular degeneration and presenting normal visual acuity. Ophthalmologica. 1995; 209: 194-8.

7. Hogg R.E., Chakravarthy U. Visual function and dysfunction in early and late age-related maculopathy. Progress in Retinal and Eye Research. 2006; 25: 249-76.


Review

For citations:


Eskina E.N., Belogurova A.V., Stepanova M.A. Clinical effectiveness of nutrof total supplement for Dry age-related macular Degeneration. Russian Ophthalmological Journal. 2016;9(2):90-95. (In Russ.) https://doi.org/10.21516/2072-0076-2016-9-2-90-95

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ISSN 2072-0076 (Print)
ISSN 2587-5760 (Online)